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Detailed atlas of the mammalian primary motor cortex will provide a springboard for future research

The NIH Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative Cell Census Network (BICCN) has unveiled an atlas of cell types and an anatomical neuronal wiring diagram for the mammalian primary motor cortex, derived from detailed studies of mice, monkeys, and humans.

6 Oct 2021

Chinese and Laotian Americans more likely to be diagnosed with nasopharyngeal cancer

Chinese Americans and Laotian Americans were over 10 and 14 times more likely to be diagnosed with nasopharyngeal cancer, respectively, than non-Hispanic white Americans, with incidence rates surpassing other Asian American subgroups, according to results presented at the virtual 14th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held October 6-8, 2021.

6 Oct 2021

Elevated allostatic load may impact treatment completion and breast cancer survival outcomes

Elevated allostatic load was associated with a lower likelihood of completing chemotherapy and a lower overall survival rate in patients with lymph node-positive or high-risk lymph node-negative HER2-negative breast cancer, according to results presented at the 14th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved, held online October 6-8, 2021.

6 Oct 2021

Research on twins indicates strong genetic influences in COVID-19

A new study discusses the strong possibility of multifactorial causation for SARS-CoV-2 infection using data from twin studies.

6 Oct 2021

KU Leuven researchers develop an ultrapotent inhibitor of dengue virus

Researchers at the KU Leuven Rega Institute and CD3 have developed an ultrapotent inhibitor of the dengue virus, which causes the tropical disease known as dengue.

6 Oct 2021

New understanding of cellular defects related to Cystic Fibrosis may pave the way for treatments

A team in the College of Medicine led by Drs. Juan Ianowski (PhD) and Julian Tam (MD) found that sodium transport is abnormal in lungs with CF.

6 Oct 2021

Depression during pregnancy linked with chemical modifications to placental genes

Episodes of maternal stress or depression during pregnancy are associated with chemical modifications to placental genes, according to a study by researchers from the National Institutes of Health.

6 Oct 2021

Collins’ skillful piloting helped NIH steer clear of political minefields

It's remarkable that the reputation of the National Institutes of Health has remained mostly intact through the covid-19 pandemic, even as other federal science agencies, including the Food and Drug Administration and Centers for Disease Control and Prevention, have come under partisan fire.

6 Oct 2021

Gene expression changes during acute SARS-CoV-2 infection may decide long-COVID symptoms

A team of US-based scientists has recently revealed the changes in gene expression profiles associated with the long-term consequences of COVID-19.

6 Oct 2021

Enisamium shows potential as antiviral therapy for COVID-19

Researchers studied the effect of enisamium on the growth and proliferation of Caco-2 and normal human bronchial epithelial cells.

6 Oct 2021

First of its kind ‘living medicine’ designed to treat antibiotic-resistant bacteria on medical implants

Researchers at the Centre for Genomic Regulation and Pulmobiotics S.L have created the first 'living medicine' to treat antibiotic-resistant bacteria growing on the surfaces of medical implants. The researchers created the treatment by removing a common bacteria's ability to cause disease and repurposing it to attack harmful microbes instead.

6 Oct 2021

Study provides new insights into how cannabis extracts may work to treat epilepsy

Research from pharmacologists at the University of Sydney provides new insights into how cannabis extracts may work to treat epilepsy.

6 Oct 2021

Researchers identify mechanism that can lead to deafness in rare Norrie disease

A team of Mass Eye and Ear Scientists led by Albert Edge, PhD, working with research fellow Yushi Hayashi, MD, PhD, has identified the mechanism that can lead to deafness in the rare syndrome, Norrie disease.

5 Oct 2021

Study uncovers a gene that plays key role in the evolution of limb development

University of Kentucky College of Medicine researchers were part of a new study that gives insight into how limb development evolved in vertebrates.

5 Oct 2021

Cysteamine inhibits SARS-CoV-2 variants of concern in vitro

Researchers in the United States have shown that a compound currently used to treat cystinosis exhibits broad antiviral activity against variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

5 Oct 2021

Structural differences in the brain may explain why siblings differ in risk of developing conduct disorder

Structural differences in the area of the brain responsible for decision making could explain why two siblings living in the same family might differ in their risk of developing the condition conduct disorder.

5 Oct 2021

A possible protective genetic polymorphism in COVID-19

A new study discusses the role of a mucin gene enhancer on the clinical phenotype of the COVID-19.

5 Oct 2021

Racism a strong factor in Black women’s high rate of premature births, study finds

The tipping point for Dr. Paula Braveman came when a longtime patient of hers at a community clinic in San Francisco's Mission District slipped past the front desk and knocked on her office door to say goodbye. He wouldn't be coming to the clinic anymore, he told her, because he could no longer afford it.

5 Oct 2021

New mathematical tool used to study the genetic interactions associated with cancer

Biologists at Cold Spring Harbor Laboratory are using a mathematical approach developed in CSHL Assistant Professor David McCandlish's lab to find solutions to a diverse set of biological problems.

5 Oct 2021

Review explores the role of cellular senescence in lymphoid organ dysfunction and immunosenescence

Aging-US published "Cellular senescence in lymphoid organs and immunosenescence" which reported that immunosenescence is a multi-faceted phenomenon at the root of age-associated immune dysfunction.

5 Oct 2021

Genetic News and Research

Detailed atlas of the mammalian primary motor cortex will provide a springboard for future research

Chinese and Laotian Americans more likely to be diagnosed with nasopharyngeal cancer

Elevated allostatic load may impact treatment completion and breast cancer survival outcomes

Research on twins indicates strong genetic influences in COVID-19

KU Leuven researchers develop an ultrapotent inhibitor of dengue virus

New understanding of cellular defects related to Cystic Fibrosis may pave the way for treatments

Depression during pregnancy linked with chemical modifications to placental genes

Collins’ skillful piloting helped NIH steer clear of political minefields

Gene expression changes during acute SARS-CoV-2 infection may decide long-COVID symptoms

Enisamium shows potential as antiviral therapy for COVID-19

First of its kind ‘living medicine’ designed to treat antibiotic-resistant bacteria on medical implants

Study provides new insights into how cannabis extracts may work to treat epilepsy

Researchers identify mechanism that can lead to deafness in rare Norrie disease

Study uncovers a gene that plays key role in the evolution of limb development

Cysteamine inhibits SARS-CoV-2 variants of concern in vitro

Structural differences in the brain may explain why siblings differ in risk of developing conduct disorder

A possible protective genetic polymorphism in COVID-19

Racism a strong factor in Black women’s high rate of premature births, study finds

New mathematical tool used to study the genetic interactions associated with cancer

Review explores the role of cellular senescence in lymphoid organ dysfunction and immunosenescence

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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