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Cancer survivors benefit from healthy lifestyle

Australia’s first community-based Cancer Survivors Centre, which is based at the University of New South Wales, has joined the Dry July campaign in a bid to pinpoint the vital role a healthy lifestyle plays in fending off cancer and the after-effects of the disease.

26 Jun 2012

Targeted delivery of therapeutic gene can effectively treat Pompe disease

Gene therapy to replace the protein missing in Pompe disease can be effective if the patient's immune system does not react against the therapy. Targeted delivery of the gene to the liver, instead of throughout the body,suppresses the immune response, improving the therapeutic effect, according to an article published in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc.

26 Jun 2012

Long-term intensive combination lipid therapy may be effective against atherosclerotic disease

For the first time, a study has found that intensive cholesterol therapy involving a combination of drugs for 20 years may be more effective over the long run than taking a single statin medication.

26 Jun 2012

Flavocoxid liver damage reported

A prescription medical food used to treat osteoarthritis may induce reversible liver damage in some users, suggests research published in the Annals of Internal Medicine.

25 Jun 2012

Deferasirox reduces elevated iron levels in patients with myelodysplastic syndrome

Researchers at Moffitt Cancer Center and colleagues at six other institutions have recently tested a treatment for patients with myelodysplastic syndrome, or MDS, a blood-related malignancy that involves the ineffective production of blood cells, leaving patients anemic and in need of frequent blood transfusions. Because the body has no natural means to reduce iron that accumulates from repeated transfusions, patients' organs can become iron overloaded, leading to heart failure, liver injury, susceptibility to infection, and other complications.

23 Jun 2012

Scientists identify novel animal reservoir for tick-borne diseases

A team of scientists at Washington University in St. Louis has been keeping a wary eye on emerging tick-borne diseases in Missouri for the past dozen years, and they have just nailed down another part of the story.

23 Jun 2012

Wake Forest Baptist researchers achieve early milestone in lab-engineered kidney project

Regenerative medicine researchers at Wake Forest Baptist Medical Center have reached an early milestone in a long-term project that aims to build replacement kidneys in the lab to help solve the shortage of donor organs.

23 Jun 2012

Shanghai Institutes of Preventative Medicine, Gentris sign MOU to advance personalized medicine

Gentris Corporation, a global leader in the application of genomic biomarkers to clinical studies, announced today that it has signed a Memorandum of Understanding with the Shanghai Institutes of Preventative Medicine to advance global personalized medicine.

22 Jun 2012

IU gastroenterologist develops first guidelines for diagnosis and management of NAFLD

An Indiana University School of Medicine gastroenterologist led a team of distinguished physicians who developed the first guidelines for diagnosis and management of non-alcoholic fatty liver disease.

22 Jun 2012

Study: Unexpected activity of estrogenic compounds during early stages of embryonic development

Chemicals in the environment that mimic estrogen can strongly influence the development of humans and other animals. New research to be presented at the 2012 International Zebrafish Development and Genetics Conference, held June 20-24 in Madison, Wisconsin, reveals that these substances may act even earlier than previously realized, at the very beginning stages of embryonic development.

22 Jun 2012

Aeterna Zentaris announces perifosine Phase 1 trial on neuroblastoma

Aeterna Zentaris Inc. today announced that Phase 1 trial results for its oral PI3K/Akt inhibitor, perifosine, showed the drug's activity against chemo-resistant and radio-resistant neuroblastoma, while allowing good quality of life and sparing vital organs. Neuroblastoma is a type of childhood cancer which usually begins in nerve tissues.

22 Jun 2012

Largest study to examine impact of gastric sleeve surgery on pre-transplant obese patients

Morbidly obese patients with end-stage organ failure may improve their chances for successful organ transplantation after laparoscopic sleeve gastrectomy, according to a new study presented here at the 29th Annual Meeting of the American Society for Metabolic & Bariatric Surgery (ASMBS).

21 Jun 2012

FDA grants Orphan Drug Designation to Medgenics’ INFRADURE Biopump

Medgenics, Inc., the developer of Biopump, a novel technology for the sustained production and delivery of therapeutic proteins in patients using their own tissue, today announced that its INFRADURE Biopump has received Orphan Drug Designation from the U.S. Food and Drug Administration (FDA) Office of Orphan Products Development (OOPD) for the treatment of hepatitis D.

21 Jun 2012

Bariatric procedure increases risk of alcohol use disorders two years after surgery

Adults who had a common bariatric surgery to lose weight had a significantly higher risk of alcohol use disorders (AUD) two years after surgery, according to a study by a National Institutes of Health research consortium.

20 Jun 2012

HCV suppression reduces liver damage

Profound suppression of the hepatitis C virus reduces long-term hepatic inflammation and fibrosis even in patients who do not achieve a sustained virologic response, research demonstrates.

19 Jun 2012

Pediatric treatment regime for ALL patients improves chances of long-term survival

Acute lymphoblastic leukemia (ALL), usually found in pediatric patients, is far more rare and deadly in adolescent and adult patients. According to the National Marrow Donor Program, child ALL patients have a higher than 80 percent remission rate, while the recovery rate for adults stands at only 40 percent.

18 Jun 2012

Researchers engineer nanoparticles that show great promise for MM

Researchers from the University of Notre Dame have engineered nanoparticles that show great promise for the treatment of multiple myeloma (MM), an incurable cancer of the plasma cells in bone marrow.

16 Jun 2012

Study calls for overhaul in health care practices for elderly prisoners

Soaring numbers of older, sicker prisoners are causing an unprecedented health care challenge for the nation's criminal justice system, according to a new UCSF report.

15 Jun 2012

Transplantation of tissue-engineered vein is a success and offers hope for patients who lack suitable veins for dialysis or bypass surgery

The first biologically tissue-engineered vein grown from a patient’s own stem cells has been successfully transplanted into a 10-year-old girl with portal vein obstruction, dramatically enhancing her quality of life.

15 Jun 2012

Breast milk protects against oral transmission of HIV

More than 15 percent of new HIV infections occur in children. Without treatment, only 65 percent of HIV-infected children will live until their first birthday, and fewer than half will make it to the age of two. Although breastfeeding is attributed to a significant number of these infections, most breastfed infants are not infected with HIV, despite prolonged and repeated exposure.

15 Jun 2012

Liver News and Research

Cancer survivors benefit from healthy lifestyle

Targeted delivery of therapeutic gene can effectively treat Pompe disease

Long-term intensive combination lipid therapy may be effective against atherosclerotic disease

Flavocoxid liver damage reported

Deferasirox reduces elevated iron levels in patients with myelodysplastic syndrome

Scientists identify novel animal reservoir for tick-borne diseases

Wake Forest Baptist researchers achieve early milestone in lab-engineered kidney project

Shanghai Institutes of Preventative Medicine, Gentris sign MOU to advance personalized medicine

IU gastroenterologist develops first guidelines for diagnosis and management of NAFLD

Study: Unexpected activity of estrogenic compounds during early stages of embryonic development

Aeterna Zentaris announces perifosine Phase 1 trial on neuroblastoma

Largest study to examine impact of gastric sleeve surgery on pre-transplant obese patients

FDA grants Orphan Drug Designation to Medgenics’ INFRADURE Biopump

Bariatric procedure increases risk of alcohol use disorders two years after surgery

HCV suppression reduces liver damage

Pediatric treatment regime for ALL patients improves chances of long-term survival

Researchers engineer nanoparticles that show great promise for MM

Study calls for overhaul in health care practices for elderly prisoners

Transplantation of tissue-engineered vein is a success and offers hope for patients who lack suitable veins for dialysis or bypass surgery

Breast milk protects against oral transmission of HIV

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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