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Newly revised classification tool for standardized diagnostic reporting of melanocytic lesions

With the growing number of skin biopsies performed annually for suspected melanoma, a simple, easily understood standardized classification system for melanocytic lesions is increasingly important to aid pathologists and clinicians who examine millions of tissue samples each year and to alleviate patient confusion and anxiety.

11 Jan 2023

Study evaluates the efficacy of complementary use of corticosteroid treatment for community-acquired pneumonia

Announcing a new publication for Acta Materia Medica journal. The objective of this study was to systematically evaluate the clinical efficacy of the complementary use of corticosteroids in the treatment of community-acquired pneumonia (CAP).

11 Jan 2023

Antivenom could prevent the appearance of necrotic skin lesion after brown recluse spider bites

One of the most dreaded effects of the bite of the brown recluse spider (Loxosceles spp) is the appearance of a necrotic skin lesion, but a clinical study by Brazilian researchers recently reported in PLOS Neglected Tropical Diseases shows that the problem can be solved by administering antivenom, especially if this is done within 48 hours of the incident.

11 Jan 2023

Investigational T-cell therapy shows antiviral efficacy and safety in cancer patients treated with stem cell transplant

Posoleucel, an investigational allogeneic off-the-shelf T-cell therapy that simultaneously targets six different viruses, demonstrated promising antiviral efficacy and safety in a phase II study of patients who had undergone stem cell transplantation to treat their cancer or other blood diseases.

11 Jan 2023

Study on bacterial infection in older individuals

The older population is prone to microbial infections, which can lead to death. Hence, it is important to understand why this group is vulnerable to microbial infection, especially bacterial infection. A recent Scientific Reports study linked data from two sources to understand the determining factors for microbial infection in the older population in the UK.

11 Jan 2023

CAR T cell therapy may enhance the effectiveness of surgery for solid tumors

CAR T cell therapy, an approach which reprograms patients' own immune cells to attack their blood cancers, may enhance the effectiveness of surgery for solid tumors, according to a preclinical study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

11 Jan 2023

Medicare policy change may lead to increased inequities in access to heart transplants

A change to Medicare policy surrounding heart transplant may lead to increased inequities in access to transplant for patients with heart failure, a Michigan Medicine study finds.

11 Jan 2023

New genetic test could guide the treatment of ovarian cancer

Researchers have developed an optimized genetic test for ovarian cancer, which helps accurately target an effective but expensive medication.

11 Jan 2023

Study reveals how inflammation alters the tumor microenvironment in acute myeloid leukemia

Severe inflammation weakens the body's ability to kill cancerous blood cells in people with acute myeloid leukemia (AML), a new study shows.

11 Jan 2023

Ringlike peripheral high iodine concentration for differentiating pulmonary metastasis from lung cancer

According to an accepted manuscript published in ARRS' American Journal of Roentgenology (AJR), ringlike peripheral high iodine concentration maps from dual-energy CT (DECT) can help guide management in patients with known lung cancer and an indeterminate solitary nodule.

11 Jan 2023

Combination therapy could be a safe choice for oral opioid maintenance treatment during pregnancy

Current guidelines recommend that pregnant women with opioid use disorder be prescribed either methadone or buprenorphine, but these drugs too have significant potential for abuse.

11 Jan 2023

UC research could lead to possible treatments for scoliosis in the future

How cells shape complex tissues and organs during embryo development, which makes us what we are, has many mysteries.

11 Jan 2023

Simple method increases the efficacy of T cell therapy by cytokine conjugation

The recent years have seen a wave of adoptive cell therapies (ACTs), a type of immunotherapy in which T cells (T cell transfer therapy) and other immune cells are obtained from patients, activated and multiplied outside the body, and infused in larger numbers back into the blood circulation to help fight cancers.

11 Jan 2023

Review shows metformin usage to be associated with better COVID-19 outcomes

Researchers reported on the potential association between metformin usage and coronavirus disease 2019 (COVID-19) outcomes.

11 Jan 2023

The decision of where to seek care is complicated by the multitude of options

One evening in February 2017, Sarah Dudley's husband, Joseph, started to feel sick. He had a high fever, his head and body ached, and he seemed disoriented, she said. The Dudleys had a decision to make: go to the hospital emergency room or to an urgent care clinic near their home in Des Moines, Iowa.

11 Jan 2023

Hospital News and Research

Newly revised classification tool for standardized diagnostic reporting of melanocytic lesions

Study evaluates the efficacy of complementary use of corticosteroid treatment for community-acquired pneumonia

Antivenom could prevent the appearance of necrotic skin lesion after brown recluse spider bites

Investigational T-cell therapy shows antiviral efficacy and safety in cancer patients treated with stem cell transplant

Study on bacterial infection in older individuals

CAR T cell therapy may enhance the effectiveness of surgery for solid tumors

Medicare policy change may lead to increased inequities in access to heart transplants

New genetic test could guide the treatment of ovarian cancer

Study reveals how inflammation alters the tumor microenvironment in acute myeloid leukemia

Ringlike peripheral high iodine concentration for differentiating pulmonary metastasis from lung cancer

Combination therapy could be a safe choice for oral opioid maintenance treatment during pregnancy

UC research could lead to possible treatments for scoliosis in the future

Simple method increases the efficacy of T cell therapy by cytokine conjugation

Review shows metformin usage to be associated with better COVID-19 outcomes

The decision of where to seek care is complicated by the multitude of options

MIS-C more common and severe than previously thought

Blood-based markers could lead to earlier detection of Alzheimer's disease

Certain type of glial cell plays a major role in spatial learning

Medicaid expansion led to improved postpartum health for low-income birthing people

Drug combination elicits efficacious anti-tumor immunity against immunotherapy-resistant cancers

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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