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Treatment with immune-boosting protein and radiation improves survival in mice with glioblastoma

Glioblastoma, an aggressive cancer in the brain or spinal cord, has proven stubbornly resistant to newer immunotherapies. And radiation and chemotherapy, the standard treatment for glioblastoma, result in fewer than 10% of patients surviving longer than five years after diagnosis.

19 Jan 2022

SARS-CoV-2 vaccination of convalescents suggested to boost neutralization capacity against variants

A new study assessed the neutralization capacity of sera from convalescents—some even vaccinated—against the Wuhan (D614G), Delta and Omicron variants of SARS-CoV-2.

19 Jan 2022

Independent drug action responsible for greater clinical efficacy of combination cancer therapies

Independent drug action, not synergy nor additivity, accounted for the clinical efficacy of nearly all examined combination therapies involving immune checkpoint inhibitors in clinical trials, according to results from a retrospective analysis.

19 Jan 2022

Early gender-affirming hormone therapy for transgender teens leads to better mental health

For transgender people, starting gender-affirming hormone treatment in adolescence is linked to better mental health than waiting until adulthood, according to new research led by the Stanford University School of Medicine.

19 Jan 2022

Addition of hormone therapy to radiotherapy treatments improves survival in prostate cancer patients

Prostate cancer is the leading cause of cancer in men worldwide, and radiotherapy is one of the common forms of treatment.

18 Jan 2022

Preconception weight loss may not increase obese woman's chances of delivering a healthy baby

Health care professionals often encourage women with obesity to lose weight prior to trying to conceive or start infertility treatments.

18 Jan 2022

Partial bone marrow transplant can dramatically improve survival of mice with cystic fibrosis

Scientists at La Jolla Institute for Immunology have found they can dramatically improve survival of mice with cystic fibrosis through a partial bone marrow transplant.

18 Jan 2022

New genomic signature can spot aggressive tumor cells from primary, untreated prostate cancers

Many cases of early prostate cancer are dominated by cells that are slow-growing, often leading to a clinical decision to monitor for progression before initiating treatments that can have adverse side effects.

18 Jan 2022

Eye-tracking systems can facilitate communication with intensive care patients

Eye-tracking systems can support communication with critically ill patients in intensive care units.

18 Jan 2022

New MRI technique could pave the way to quicker assessment of multiple sclerosis

It is important that multiple sclerosis (MS) is diagnosed and treated as early as possible in order to delay progression of the disease.

18 Jan 2022

Risk factors affect cardiovascular disease risk even in patients with no coronary artery calcium

Among patients with no detectable coronary artery calcium, those who smoke, have diabetes or hypertension nonetheless have the highest risk of cardiovascular disease events, according to a study published in the journal Circulation.

18 Jan 2022

Study: Nearly 30% of people with blinding retinal disease can safely stop eye injection therapy

In a preliminary study of 106 people with "wet" age-related macular degeneration, Johns Hopkins Medicine researchers report that as many as a third of those with the blinding retinal disease may someday be able to safely stop eye injection therapy without further vision loss.

18 Jan 2022

Evidence that monoclonal antibodies can reduce COVID-19 (Delta) mortality

Researchers prevent evidence on the efficacy of neutralizing monoclonal antibodies in treating COVID-19.

17 Jan 2022

Efficacy and safety of mRNA-based SARS-CoV-2 vaccination in immuno-compromised subjects

A team of researchers assessed the immune response after administering a SARS-COV-2 vaccine in immuno-compromised subjects who are potentially at an increased risk to experience severe COVID-19 and inadequate response to SARS-CoV2 vaccination.

17 Jan 2022

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

In a new study, researchers used per protocol bronchoalveolar lavage fluid (BALF) samples after intubation to evaluate the transcriptomic profiles of the local pulmonary host responses during early-stage severe coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (CARDS), non-COVID-19 ARDS, and sepsis.

17 Jan 2022

New model to identify biological markers in patients with COVID-19 and other illnesses

Investigators who recently developed a mathematical model that indicated why treatment responses vary widely among individuals with COVID-19 have now used the model to identify biological markers related to these different responses.

17 Jan 2022

Topical antiseptic Acriflavine inhibits SARS-CoV-2 and other betacoronaviruses

A new study, published in the journal Cell Chemical Biology, has reported the discovery of acriflavine (ACF), an effective inhibitor of SARS-CoV-2. This drug is a mixture of trypaflavines (3,6-diamino-10-methylacridinium chloride and 3,6-diamino-3-methylacridinium chloride) and proflavine (3,6-diaminoacridine).

16 Jan 2022

Rapid antigen test for SARS-CoV-2 proves to be highly accurate for pediatric populations

In a large prospective study of just over 1,000 patients ages 17 and younger who were seen at the Baltimore Convention Center Field Hospital (BCCFH) testing site during a seven-month period last year, researchers from Johns Hopkins Medicine and collaborating institutions report that a rapid antigen test for SARS-CoV-2 — the virus that causes COVID-19 — proved highly accurate when compared to the established standard virus detection method: the polymerase chain reaction (PCR).

16 Jan 2022

Even mild SARS-CoV-2 respiratory-only infection can cause long-term neurologic damage

A new bioRxiv* preprint study led by Michelle Monje of Stanford University in California finds that a mild COVID-19 infection can produce long-term neurological damage. Persistent cognitive complications are one of many symptoms of long COVID, and the latest results suggest the severity of COVID-19 induced brain fog is similar to cancer’s “chemobrain.”

16 Jan 2022

Exploring the relationship between stem cells and COVID-19

Though COVID-19-related stem cell clinical research is still in its infancy, stem cell treatment offers extensive clinical application possibilities and a far-reaching relevance thanks to ongoing exploration of stem cell clinical research and data mining.

14 Jan 2022

Therapy News and Research

Treatment with immune-boosting protein and radiation improves survival in mice with glioblastoma

SARS-CoV-2 vaccination of convalescents suggested to boost neutralization capacity against variants

Independent drug action responsible for greater clinical efficacy of combination cancer therapies

Early gender-affirming hormone therapy for transgender teens leads to better mental health

Addition of hormone therapy to radiotherapy treatments improves survival in prostate cancer patients

Preconception weight loss may not increase obese woman's chances of delivering a healthy baby

Partial bone marrow transplant can dramatically improve survival of mice with cystic fibrosis

New genomic signature can spot aggressive tumor cells from primary, untreated prostate cancers

Eye-tracking systems can facilitate communication with intensive care patients

New MRI technique could pave the way to quicker assessment of multiple sclerosis

Risk factors affect cardiovascular disease risk even in patients with no coronary artery calcium

Study: Nearly 30% of people with blinding retinal disease can safely stop eye injection therapy

Evidence that monoclonal antibodies can reduce COVID-19 (Delta) mortality

Efficacy and safety of mRNA-based SARS-CoV-2 vaccination in immuno-compromised subjects

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

New model to identify biological markers in patients with COVID-19 and other illnesses

Topical antiseptic Acriflavine inhibits SARS-CoV-2 and other betacoronaviruses

Rapid antigen test for SARS-CoV-2 proves to be highly accurate for pediatric populations

Even mild SARS-CoV-2 respiratory-only infection can cause long-term neurologic damage

Exploring the relationship between stem cells and COVID-19

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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