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Study: Gadolinium deposition in brain not associated with dosage

Investigators at Children's Hospital Los Angeles have determined that in children receiving gadolinium as a contrast agent to enhance MRI examinations, signal changes attributed solely to deposition of this material in the brain are not dependent on the amount of gadolinium administered but rather these changes are seen in association with other factors such as the presence of brain tumors and treatment using brain irradiation. Results of the study were just published in the journal, Radiology.

15 May 2018

Immune system can produce 'universal antibodies' against various microorganisms

Bacteria and other microorganisms display structures from sugar molecules on their surfaces. These sugar structures play an important role for immune defense.

15 May 2018

Genetic fixer-uppers could aid in predicting prognosis of patients with bladder cancer

Mutations in genes that help repair damage to DNA may aid in predicting the prognosis of patients with bladder and other related cancers, according to researchers.

15 May 2018

Invasive cancers that are born to be bad show detectable differences from harmless tumors

Do metastatic cancer tumors "break bad" or are they "born bad"? This question is an essential mystery in cancer early detection and treatment. Lacking a clear answer, patients are given the same aggressive therapies when small, abnormal clusters of cells are discovered early, even though they might well be harmless.

15 May 2018

Researchers discover unique mechanism that regulates tumor growth in lung cancer

Lung cancer is the third most common type of cancer in Germany and the disease affects both men and women. However, immunotherapies are successful in only 20 percent of cases.

14 May 2018

Study uncovers promising new line of attack against aggressive prostate cancer

UC San Francisco researchers have discovered a promising new line of attack against lethal, treatment-resistant prostate cancer. Analysis of hundreds of human prostate tumors revealed that the most aggressive cancers depend on a built-in cellular stress response to put a brake on their own hot-wired physiology.

14 May 2018

Protein researchers identify several new potential targets for cancer

In a new study based on mouse cells internationally leading protein researchers have identified several new potential targets using state-of-the-art technology, many of which could be employed for future treatment of different types of cancers and diseases.

14 May 2018

Researchers use spheroids to screen for potential cancer drugs

Researchers from The Scripps Research Institute have reported a new and more effective way of screening for potential cancer drugs.

14 May 2018

Researchers report advances in efforts to improve treatment, prognosis of colorectal cancers

Georgios Margonis, M.D., Ph.D., a surgical oncology fellow at the Johns Hopkins University School of Medicine, and Matthew Weiss, M.D., surgical director of the Johns Hopkins Liver and Pancreas Cancer Multidisciplinary Clinics, report advances in efforts to improve the treatment and prognosis of colorectal cancers that have spread to the liver.

14 May 2018

New technique aims to expand understanding of mechanical forces existing between cells

A new technique that uses tiny elastic balls filled with fluorescent nanoparticles aims to expand the understanding of the mechanical forces that exist between cells, researchers report.

14 May 2018

Study gives insight into how signals enter cancer cells and drive aggressive growth

The outside of a cancer cell is bombarded by signals. They come from the immune system, supporting tissues and other structures. But how do those signals impact cancer?

14 May 2018

New therapeutic strategy exploits acquired vulnerability in drug-resistant cancer

Cancer cells that develop resistance to drugs, pay a price for this, by simultaneously developing a new vulnerability. If this acquired vulnerability can be identified, it may be exploited clinically.

10 May 2018

Study finds way to better treat men with locally advanced prostate cancer

A new study published today has found a way to identify men with locally advanced prostate cancer who are less likely to respond well to radiotherapy.

10 May 2018

TGen scientists develop new quality-control assay to detect cancer from patient's blood sample

Imagine how much patients could benefit if you could discover the presence of cancer, and even how that cancer develops over time, with a simple blood test.

10 May 2018

Depleted metabolic enzymes contribute to tumor growth in renal cancer

Kidney cancer, one of the ten most prevalent malignancies in the world, has increased in incidence over the last decade, likely due to rising obesity rates.

10 May 2018

Aravive Biologics demonstrates proof-of-mechanism for AVB-S6-500 in ongoing phase 1 study

Aravive Biologics, Inc. announced today that the company has demonstrated clinical proof-of-mechanism for AVB-S6-500 in neutralizing GAS6, based on analysis of the single ascending dose portion of the ongoing Phase 1 study.

10 May 2018

Scientists identify mutation that makes tumor cells resistant to breast and ovarian cancer drug

Scientists have identified a mutation that gives cancer cells resistance to the breakthrough cancer treatment olaparib and other PARP inhibitors.

10 May 2018

Researchers discuss challenges and barriers faced in the development of personalized medicine

Personalized medicine has the potential to improve the treatment and care of patients. This promising approach has already borne fruit, with a handful of targeted therapies for cancer now in use.

10 May 2018

Researchers identify six genes that predispose carriers to develop medulloblastoma

Researchers have identified six genes that predispose carriers to develop the brain tumor medulloblastoma and have used the discovery to craft genetic counseling and screening guidelines. The study appears today in the journal The Lancet Oncology.

10 May 2018

Researchers develop artificial intelligence method to help cancer patients worldwide

Before performing radiation therapy, radiation oncologists first carefully review medical images of a patient to identify the gross tumor volume -- the observable portion of the disease. They then design patient-specific clinical target volumes that include surrounding tissues, since these regions can hide cancerous cells and provide pathways for metastasis.

10 May 2018

Tumor News and Research

Study: Gadolinium deposition in brain not associated with dosage

Immune system can produce 'universal antibodies' against various microorganisms

Genetic fixer-uppers could aid in predicting prognosis of patients with bladder cancer

Invasive cancers that are born to be bad show detectable differences from harmless tumors

Researchers discover unique mechanism that regulates tumor growth in lung cancer

Study uncovers promising new line of attack against aggressive prostate cancer

Protein researchers identify several new potential targets for cancer

Researchers use spheroids to screen for potential cancer drugs

Researchers report advances in efforts to improve treatment, prognosis of colorectal cancers

New technique aims to expand understanding of mechanical forces existing between cells

Study gives insight into how signals enter cancer cells and drive aggressive growth

New therapeutic strategy exploits acquired vulnerability in drug-resistant cancer

Study finds way to better treat men with locally advanced prostate cancer

TGen scientists develop new quality-control assay to detect cancer from patient's blood sample

Depleted metabolic enzymes contribute to tumor growth in renal cancer

Aravive Biologics demonstrates proof-of-mechanism for AVB-S6-500 in ongoing phase 1 study

Scientists identify mutation that makes tumor cells resistant to breast and ovarian cancer drug

Researchers discuss challenges and barriers faced in the development of personalized medicine

Researchers identify six genes that predispose carriers to develop medulloblastoma

Researchers develop artificial intelligence method to help cancer patients worldwide

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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