Bacterial News and Research

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Trius Therapeutics starts U.S. phase I trial for Oxazolidinone antibacterial drug

Trius Therapeutics, Inc. has announced that it initiated its first Phase 1 clinical trial of TR-701, an antibacterial drug candidate intended for treatment of patients with serious Gram-positive bacterial infections, including those caused by MRSA and other drug-resistant strains.

9 Jan 2008

Take care of your teeth and gums for a healthy heart

Each year, cardiovascular disease kills more Americans than cancer. And while most people are aware that lifestyle choices such as eating right, getting enough exercise and quitting smoking can help prevent cardiovascular disease, they may not know that by just brushing and flossing their teeth each day, they might also be avoiding this potentially lethal condition.

9 Jan 2008

Genital mycoplasmas are a frequent cause of congenital fetal infection

Premature babies are subject to a host of threats that can result in fetal/neonatal disease.

7 Jan 2008

Chlamydia trachomatis genome sheds light on an emerging infection

Researchers have decoded the genome of the strain of Chlamydia that causes the most severe, invasive form of the disease. Their study shows that, despite recent increases in invasive infections, the strain has remained virtually unchanged for 40 years.

7 Jan 2008

FDA clears test for 12 specific respiratory viruses

The U.S. Food and Drug Administration has cleared for marketing a test that simultaneously detects and identifies 12 specific respiratory viruses.

4 Jan 2008

Urinary tract infections from the catheter - most common hospital-acquired infection

One in four Americans in the hospital right now has a urinary catheter. One percent of them will get a urinary tract infection from that catheter.

4 Jan 2008

Cases of meningitis caused by herpes simplex virus set to rise

Viral meningitis is common, but many cases go unreported, say researchers in this week's BMJ.

4 Jan 2008

Polyphenols in wine may help prevent cavities

A class of chemicals in red wine grapes may significantly reduce the ability of bacteria to cause cavities, according to a study published recently in the Journal of Agricultural and Food Chemistry.

3 Jan 2008

Researchers seek to make cavity-causing bacteria self-destruct

Bacteria that eat sugar and release cavity-causing acid onto teeth may soon be made dramatically more vulnerable to their own acid.

3 Jan 2008

Three-drug cocktail improves outcomes in glioblastoma multiforme

New research at Wake Forest University Baptist Medical Center suggests that a three-drug cocktail may one day improve outcomes in patients with glioblastoma multiforme (GBM), a type of brain tumor with a dismal prognosis.

2 Jan 2008

New drug targets may fight tuberculosis and other bacterial infections in novel way

Over the course of the 20th Century, doctors waged war against infectious bacterial illness with the best new weapon they had: antibiotics.

28 Dec 2007

Paradigm shift in TB: virulence factors, not antibiotics

Over the course of the 20th Century, doctors waged war against infectious bacterial illness with the best new weapon they had: antibiotics.

27 Dec 2007

Research could turn the tables on superbugs

Scientists in Australia and America believe they have found a way to deal with the increasing antibiotic resistance of deadly superbugs such as MRSA.

27 Dec 2007

Australian researchers tackle antibiotic resistance

The development of antibiotic resistant strains of bacteria that are problematic and expensive to treat is a major healthcare problem around the world. The "selective pressure" of antibiotic usage inevitably results in the emergence and proliferation of resistant bacteria.

20 Dec 2007

Authorities in the U.S. say hold back on children's Hib vaccine

Health authorities in U.S. are advising doctors to defer giving booster shots of a childhood vaccine following suspicions that production equipment may not have been properly sterilized.

20 Dec 2007

Addition of antibiotics to MS therapy could slow down progression of the disease

Researchers from Louisiana State University in the U.S. are suggesting that the addition of antibiotics to standard drug therapy for multiple sclerosis, may slow down the progress of the disease.

19 Dec 2007

Rifapentine is back for tuberculosis

It has no current market, not even a prescription price. Its makers stopped commercial production years ago, because demand was so low.

18 Dec 2007

Intracellular bacterial communities in cystitis; rifapentine cures TB in mouse model; and more

A study published this week in the open access journal PLoS Medicine presents convincing evidence that intracellular bacterial communities (IBCs) commonly exist in women with bladder infections and may contribute to the recurrence of these infections.

18 Dec 2007

Hospitalizations for children with HIV drop by nearly two thirds

The number of infants under age 2 with HIV who were hospitalized fell by 64 percent between 1998 and 2005, according to the latest News and Numbers by the Agency for Healthcare Research and Quality.

18 Dec 2007

Bacteria that cause urinary tract infections invade bladder cells

Scientists at Washington University School of Medicine in St. Louis have found definitive proof that some of the bacteria that plague women with urinary tract infections (UTIs) are entrenched inside human bladder cells.

18 Dec 2007