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Clinical leaders, health experts and ministers convene in Downing Street for NHS Recovery Forum

Clinical leaders, health experts and ministers will convene in Downing Street for an NHS Recovery Forum today (Saturday 7 January).

6 Jan 2023

New research on DNA-repair enzyme could help enhance cancer drug development

Researchers from Rice University and St. Jude Children's Research Hospital in Memphis, Tennessee, took a close look at one of ways cells repair broken strands of DNA and discovered details that could help make a particular enzyme a promising target for precision cancer therapy.

6 Jan 2023

At-home saliva test to diagnose adrenal insufficiency makes a difference to patients' health

A study into the use of an at-home test which uses saliva rather than blood to diagnose adrenal insufficiency, which has been developed by scientists at the University of Sheffield with funding from the National Institute for Health and Care Research, and tested in Sheffield endocrine patients at Sheffield Teaching Hospitals NHS Foundation Trust, is making a difference to the health of patients and could reduce time to diagnosis.

6 Jan 2023

Low-cost intervention can make a difference to America's deadly overdose epidemic

There are no simple solutions to America's deadly overdose epidemic, which costs 100,000 lives each year and is erasing gains in life expectancy.

6 Jan 2023

Study finds older knee replacement designs to be just as effective as newer models

Older knee replacement designs are just as effective as newer models - according to new research from the Norfolk and Norwich University Hospital and University of East Anglia.

6 Jan 2023

Study shows XBB.1.5 exhibits a substantially higher hACE2-binding affinity compared to BQ.1.1 and XBB/XBB.1

Researchers investigated the reasons for the rapid advent of SARS-CoV-2 XBB.1.5, a sublineage of the Omicron recombinant mutant XBB in the USA.

6 Jan 2023

Study links epigenetic biological aging and aberrations in neural oscillatory activity in people with HIV

A new research paper was published in Aging (listed as "Aging (Albany NY)" by MEDLINE/PubMed and "Aging-US" by Web of Science) Volume 14, Issue 24, entitled, "Epigenetic aging is associated with aberrant neural oscillatory dynamics serving visuospatial processing in people with HIV."

6 Jan 2023

The risk factors and outcomes of ARDS following infection with SARS-CoV-2 in a young adult population

Researchers evaluated the outcomes and identified risk factors associated with the development of ARDS after SARS-CoV-2 infections among young adults.

6 Jan 2023

Is appropriate initial empirical antimicrobial therapy associated with lower in-hospital mortality in patients with bloodstream infections?

Researchers estimated the association between the receipt of appropriate initial empirical antibiotic treatment and in-hospital death among individuals hospitalized with BSI (bloodstream infections).

6 Jan 2023

During in-flight emergencies, Sometimes airlines’ medical kits fall short

In March, a Frontier Airlines flight was headed from Phoenix to Las Vegas when a female passenger stopped breathing. The flight attendant yelled in the cabin for help.

6 Jan 2023

Study describes the variations in drug response across genetic subtypes of childhood leukemia

Scientists at St. Jude Children's Research Hospital are reporting the most comprehensive study to date describing the variations in drug response across different genetic subtypes of acute lymphoblastic leukemia (ALL).

5 Jan 2023

New electrically conductive hydrogel scaffold supports neural cell differentiation

Brain-computer interfaces (BCIs) are a hot topic these days, with companies like Neuralink racing to create devices that connect humans' brains to machines via tiny implanted electrodes.

5 Jan 2023

Postoperative restrictive opioid protocols reduce long-term opioid use

Research at Roswell Park Comprehensive Cancer Center shows that putting a three-day limit on opioid prescriptions to treat surgical pain after hospital discharge reduces the number of patients who become chronic opioid users without compromising pain relief or recovery.

5 Jan 2023

Immune system B-cells may be better in predicting HER2-positive breast cancer treatment response

Researchers at UNC Lineberger Comprehensive Cancer Center and colleagues have found that measuring activation of immune-system B cells may be better than measuring either T-cell activation or the total number of immune cells in and around a tumor, called tumor-infiltrating lymphocytes (TILs), in predicting whether HER2-positive breast cancer responds to treatment.

5 Jan 2023

Irish study demonstrates a genetic effect on the response to obesity treatments

Collaborative research between University of Galway and Brunel University London has found that patients with severe and complicated obesity respond differently to a dietary weight loss program based on their genes.

5 Jan 2023

Cilia act as sensors to establish body left-right asymmetry during embryogenesis

Although the human body is externally symmetric across the left-right axis, there are remarkable left-right asymmetries in the shape and positioning of most internal organs including the heart, lungs, liver, stomach, and brain.

5 Jan 2023

Are patients with a history of MIS-C at increased risk of adverse reactions from COVID-19 vaccination?

Researchers investigated the reactogenicity of the COVID-19 vaccine in pediatric patients with MIS-C.

5 Jan 2023

Estimating the hospital costs associated with two of the most significant antibiotic-resistant organisms in Canada

Researchers assessed the hospital and associated resource costs related to AMR infections in Canada.

5 Jan 2023

Antibiotic concentrations in aquatic environments may pose a threat to human health

Antibiotic residues in wastewater and wastewater treatment plants in the regions around China and India risk contributing to antibiotic resistance, and the drinking water may pose a threat to human health, according to a comprehensive analysis from Karolinska Institutet published in The Lancet Planetary Health.

4 Jan 2023

New dual-action, cancer-killing vaccine tested in an advanced mouse model of glioblastoma

Scientists are harnessing a new way to turn cancer cells into potent, anti-cancer agents. In the latest work from the lab of Khalid Shah, MS, PhD, at Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, investigators have developed a new cell therapy approach to eliminate established tumors and induce long-term immunity, training the immune system so that it can prevent cancer from recurring.

4 Jan 2023

Hospital News and Research

Clinical leaders, health experts and ministers convene in Downing Street for NHS Recovery Forum

New research on DNA-repair enzyme could help enhance cancer drug development

At-home saliva test to diagnose adrenal insufficiency makes a difference to patients' health

Low-cost intervention can make a difference to America's deadly overdose epidemic

Study finds older knee replacement designs to be just as effective as newer models

Study shows XBB.1.5 exhibits a substantially higher hACE2-binding affinity compared to BQ.1.1 and XBB/XBB.1

Study links epigenetic biological aging and aberrations in neural oscillatory activity in people with HIV

The risk factors and outcomes of ARDS following infection with SARS-CoV-2 in a young adult population

Is appropriate initial empirical antimicrobial therapy associated with lower in-hospital mortality in patients with bloodstream infections?

During in-flight emergencies, Sometimes airlines’ medical kits fall short

Study describes the variations in drug response across genetic subtypes of childhood leukemia

New electrically conductive hydrogel scaffold supports neural cell differentiation

Postoperative restrictive opioid protocols reduce long-term opioid use

Immune system B-cells may be better in predicting HER2-positive breast cancer treatment response

Irish study demonstrates a genetic effect on the response to obesity treatments

Cilia act as sensors to establish body left-right asymmetry during embryogenesis

Are patients with a history of MIS-C at increased risk of adverse reactions from COVID-19 vaccination?

Estimating the hospital costs associated with two of the most significant antibiotic-resistant organisms in Canada

Antibiotic concentrations in aquatic environments may pose a threat to human health

New dual-action, cancer-killing vaccine tested in an advanced mouse model of glioblastoma

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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