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Targeting specific enzyme could combat Alzheimer’s disease on two fronts

UQ researchers have discovered a potential drug target for Alzheimer’s disease — an enzyme which has effects on both the immune and nervous systems.

19 Sep 2019

Stem cells with 'dual identity' associated with loss of smell from inflammation in chronic sinusitis

In experiments with mice and human tissue samples, Johns Hopkins Medicine researchers report evidence that neuronal stem cells in the part of the nose responsible for the sense of smell transform themselves to perpetuate the long-term inflammation in chronic sinusitis.

19 Sep 2019

Blue-green algae pose threat to patients with liver disease

Researchers are calling for new guidelines for people with pre-existing liver disease who are exposed to a toxin released by blue-green algae.

19 Sep 2019

New protein could offer a fresh target for cancer treatment

A study has revealed a drug target called the mitoNEET cell protein, which determines how materials are transported from the mitochondria to the rest of the cell.

19 Sep 2019

Researchers discover how cancer cells can trigger chronic muscle wasting condition

A solid tumor can cause muscle cells in the body to self-destruct. Many cancer patients die from the consequences. Now researchers are discovering more about how cancer cells in a tumor can take control of muscle cell wasting and trigger a chronic, serious condition.

19 Sep 2019

Toxic algae may be more harmful for people with pre-existing liver disease

Toxins produced during harmful algal blooms may be more harmful to people than previously known.

19 Sep 2019

TUM researchers identify complex interactions between bacteria and parasites

A team at the Technical University of Munich has completed the first study of the effects of a simultaneous infection with blood flukes (schistosomes) and the bacterium Helicobacter pylori - a fairly common occurrence in some parts of the world.

19 Sep 2019

NUS chemists develop new anti-cancer drug with less renal toxicity

A team of pharmacists and chemists from the National University of Singapore has developed a new anti-cancer drug that has less toxic effects to the kidneys.

18 Sep 2019

Psoriasis drug could be repurposed to treat osteosarcoma

A treatment for psoriasis could be repurposed to treat a rare but aggressive form of youth cancer, new findings from the Garvan Institute of Medical Research suggest.

18 Sep 2019

Fathers can protect their LGB kids from negative effects of discrimination on health

Lesbian, gay, and bisexual individuals who report being discriminated against but who feel close to their fathers have lower levels of C-reactive protein-a measure of inflammation and cardiovascular risk-than those without support from their fathers, finds a new study from researchers at NYU College of Global Public Health.

18 Sep 2019

Quanterix Serum Nf-L assay powers key trial and study results presented at ECTRIMS 2019

Quanterix, announce that its Simoa technology and Nf-L assays were used in many of the groundbreaking research and treatment developments.

From Quanterix 18 Sep 2019

New peptides improve memory in mice with Alzheimer’s

Alzheimer’s disease (AD) affects over 44 million people the world over. But now, neurologist Jack Jhamandas and his team have found two short peptides which, on daily injection into mice with symptoms of AD for just five weeks, led to a significant improvement.

18 Sep 2019

New results revealed from pilot stem cell study for stroke

Researchers led by Sean I. Savitz, MD, reported today in the journal Stem Cells that bone marrow cells used to treat ischemic stroke in an expanded Phase I trial were not only safe and feasible, but also resulted in enhanced recovery compared to a matched historical control group.

17 Sep 2019

Radiation therapy reduces episodes of deadly rapid heart rhythm

A single high dose of radiation aimed at the heart significantly reduces episodes of a potentially deadly rapid heart rhythm, according to results of a phase one/two study at Washington University School of Medicine in St. Louis.

17 Sep 2019

No more tears: immunization without needles

A new study published in the Journal of Investigative Dermatology reports a novel skin vaccine patch which could help effective and safe immunization by disrupting the permeability of the skin, providing a convenient and non-invasive alternative to immunization shots. This innovative technique now needs to be tested in humans.

17 Sep 2019

Study explores link between rheumatoid arthritis widespread pain and smoking

A team of researchers at the Karolinska University Hospital Huddinge in Stockholm, Sweden wanted to investigate if smoking status at the time of rheumatoid arthritis diagnosis was linked with pain spread or intensity.

16 Sep 2019

New therapeutic target for rheumatoid arthritis and type 2 diabetes

There is a growing body of knowledge that points that type 2 diabetes, a chronic disease where the blood sugar increases, is an inflammatory disease. The levels of certain inflammatory chemicals, dubbed as cytokines, are often higher in people with type 2 diabetes, than healthy people.

16 Sep 2019

New biomarkers help predict response to treatment in common brain tumor

Many scientists have noted that there is a link between inflammation or the immune response, and patient survival. One such possible relationship is the association of blood markers and the prognosis in the brain tumor called medulloblastoma.

16 Sep 2019

Gut bacterial changes influence lupus treatment results in pregnancy

The course of pregnancy, like that of true love, doesn’t always run smooth when you have lupus, correctly called systemic lupus erythematosus (SLE). This autoimmune disease is an occasionally violent, occasionally subdued, chronic inflammation that constantly smolders within multiple tissues in the body.

16 Sep 2019