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Apatorsen added to first-line chemotherapy benefits metastatic bladder cancer patients

OncoGenex Pharmaceuticals, Inc. announced that results from an exploratory analysis of the Phase 2 Borealis-1 trial showed that metastatic bladder cancer patients with poor prognostic features benefited from apatorsen 600mg added to first-line chemotherapy compared to chemotherapy alone.

2 Jun 2015

Veritas Genetics introduces genetic screen for hereditary breast and ovarian cancer risk

Boston-based Veritas Genetics is launching its mission to disrupt the genetic testing industry and bring personalized medicine and prevention to the forefront, allowing individuals to take more control of their health.

2 Jun 2015

New York Eye and Ear Infirmary of Mount Sinai observes June 1st as World Orthoptics Day

New York Eye and Ear Infirmary of Mount Sinai joins with the International Orthoptic Association to observe June 1st as World Orthoptics Day.

2 Jun 2015

Researchers identify previously unknown gene mutation that causes achromatopsia

People with achromatopsia, an inherited eye disorder, see the world literally in black and white. Worse yet, their extreme sensitivity to light makes them nearly blind in bright sunlight. Now, researchers at University of California, San Diego School of Medicine and Shiley Eye Institute at UC San Diego Health System have identified a previously unknown gene mutation that underlies this disorder.

2 Jun 2015

VBL Therapeutics reports positive results from VB-111 Phase 1/2a study in recurrent platinum-resistant Müllerian cancer

VBL Therapeutics, a late-stage clinical biotechnology company focused on the discovery, development and commercialization of first-in-class treatments for cancer, today announced positive interim results from an investigator-initiated, Phase 1/2a trial of multiple dose VB-111 in recurrent platinum-resistant Müllerian (ovarian) cancer.

2 Jun 2015

Previously unknown gene mutation linked to inherited eye disorder, achromatopsia

2 Jun 2015

Trabectedin may be better than dacarbazine for treatment of soft tissue sarcoma

Janssen Research & Development, LLC announced data from the Phase 3 multicenter study SAR3007, which demonstrated a significant improvement in progression-free survival with trabectedin (YONDELIS®) compared to dacarbazine in patients with advanced liposarcoma (LPS) or leiomyosarcoma (LMS) previously treated with an anthracycline and at least one additional chemotherapy regimen.

2 Jun 2015

Mount Sinai Health System researchers present updates on cancer vaccine clinical trials at ASCO 2015

Mount Sinai Health System faculty will be presenting research updates on a lymphoma vaccine clinical trial, the best dosing for a drug against metastatic cancer, and new treatment strategies in relapsed multiple myeloma at the American Society of Clinical Oncology annual meeting, May 29 - June 2, 2015, in Chicago.

2 Jun 2015

Study on human growth hormone for ACL tear recovery receives funding from Mark Cuban Foundation

Funding from the Mark Cuban Foundation, run by the well-known owner of the Dallas Mavericks, will allow University of Michigan scientists and physicians to study how human growth hormone may aid recovery from an ACL tear - one of the most frequent, traumatic and dreaded knee injuries among athletes.

1 Jun 2015

Precision medicine helps improve patient health and reduces risk of side effects, says Penn Medical School dean

The rapidly emerging field of precision medicine is a "disruptive innovation" that offers the possibility of remarkably fine-tuned remedies to improve patient health while minimizing the risk of harmful side effects, says J. Larry Jameson, MD, PhD, dean of the Perelman School of Medicine and executive vice president of the University of Pennsylvania for the Health System, in this week's issue of the New England Journal of Medicine.

1 Jun 2015

Study shows antibiotic prescriptions in telemedicine exams are as frequent as regular exams

Patients treated for an acute respiratory infection by a doctor on a telephone or live video are as likely to be prescribed an antibiotic as patients who are treated by a physician face-to-face for the same illness, according to a new RAND Corporation study.

1 Jun 2015

Researchers discover new source for cells that can develop into coronary vessels

The heart has its own dedicated blood supply, with coronary arteries that supply oxygen-rich blood to the heart and cardiac veins that remove deoxygenated blood. This system of vessels nourishes the heart, enabling it to pump blood to all the other organs and tissues of the body. Yet despite their critical importance, the process and molecules required for coronary vessel development have not been fully determined.

30 May 2015

Researchers uncover critical role for two proteins in chromatin structure

A team of researchers at the IRCM led by François Robert, PhD, uncovered a critical role for two proteins in chromatin structure. Their breakthrough, recently published in the scientific journal Molecular Cell, helps explain how DNA is organized in our cells. This discovery could lead to a better understanding of what causes certain types of cancer, such as lymphoma.

30 May 2015

Researchers awarded $3.86 million NIH grant to tackle the issue of 'mosaicism' in schizophrenia

Why does schizophrenia happen, and how can we improve treatment for it? These basic questions persist despite years of research on one of the most puzzling, and debilitating, mental illnesses. Now, a University of Michigan Medical School team and their colleagues will take a new approach to addressing these questions by searching for genetic clues in postmortem brain tissues of people with and without schizophrenia.

30 May 2015

Wings of Courage: New book pays tribute to Livonia girl who fought cancer

Leah James loved the color purple, Nemo and storybooks. She was also well known for her contagious smile and the phrase "my heart is happy" even when she was fighting cancer at age four.

30 May 2015

Racial socialization in early childhood may increase child's ability to excel in school

A child's ability to succeed academically is one of the strongest determinants of his or her future quality of life. In particular, it has been directly linked to overall longevity and several other critical health outcomes.

30 May 2015

New research shows wide variation in organ donation rates across the country

More than 123,000 Americans are currently waiting for lifesaving organ transplants, but 21 patients die each day because there aren't enough organs to go around. New research shows wide variation in the number of eligible organ donors whose loved ones consent to organ donation across the country.

29 May 2015

DDW 2015: Experts explore efficacy of Stretta therapy for treating chronic GERD patients

A special presentation at Digestive Disease Week 2015 featured GERD experts weighing in on their successful experience using Stretta therapy to treat challenging patient populations suffering from GERD.

29 May 2015

Differences in brain expression of RORA protein levels may lead to sex bias in autism

George Washington University researcher Valerie Hu, Ph.D., has found an important sex-dependent difference in the level of RORA protein in brain tissues of males and females. Specifically, females without autism have a slightly higher level of RORA in the frontal cortex of the brain than males without autism, while the levels of the protein are comparably lower in the brain of both males and females with autism.

29 May 2015

Amgen announces AMG 416 Phase 3 results for treatment of secondary hyperparathyroidism in CKD patients

Amgen today announced pooled data from two pivotal Phase 3, global, randomized, placebo-controlled trials evaluating AMG 416, a novel calcimimetic, for the treatment of secondary hyperparathyroidism in patients with chronic kidney disease (CKD) receiving hemodialysis.

29 May 2015

Medical School News and Research

Apatorsen added to first-line chemotherapy benefits metastatic bladder cancer patients

Veritas Genetics introduces genetic screen for hereditary breast and ovarian cancer risk

New York Eye and Ear Infirmary of Mount Sinai observes June 1st as World Orthoptics Day

Researchers identify previously unknown gene mutation that causes achromatopsia

VBL Therapeutics reports positive results from VB-111 Phase 1/2a study in recurrent platinum-resistant Müllerian cancer

Previously unknown gene mutation linked to inherited eye disorder, achromatopsia

Trabectedin may be better than dacarbazine for treatment of soft tissue sarcoma

Mount Sinai Health System researchers present updates on cancer vaccine clinical trials at ASCO 2015

Study on human growth hormone for ACL tear recovery receives funding from Mark Cuban Foundation

Precision medicine helps improve patient health and reduces risk of side effects, says Penn Medical School dean

Study shows antibiotic prescriptions in telemedicine exams are as frequent as regular exams

Researchers discover new source for cells that can develop into coronary vessels

Researchers uncover critical role for two proteins in chromatin structure

Researchers awarded $3.86 million NIH grant to tackle the issue of 'mosaicism' in schizophrenia

Wings of Courage: New book pays tribute to Livonia girl who fought cancer

Racial socialization in early childhood may increase child's ability to excel in school

New research shows wide variation in organ donation rates across the country

DDW 2015: Experts explore efficacy of Stretta therapy for treating chronic GERD patients

Differences in brain expression of RORA protein levels may lead to sex bias in autism

Amgen announces AMG 416 Phase 3 results for treatment of secondary hyperparathyroidism in CKD patients

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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