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Scientists identify neurons that play crucial roles in connecting emotions and sleep

You may have experienced sleepless nights when you were anxious, stressed or too excited. Such emotions are well-known to affect wakefulness and can even cause insomnia, though the underlying mechanisms in our brain have still been unclear.

3 Jul 2017

Wayne State researchers receive NIH grant to mimic benefits of exercise in sedentary patients

A team of researchers led by Robert Wessells, Ph.D., assistant professor of physiology in the School of Medicine at Wayne State University, has received a two-year, $423,500 grant from the National Institute on Aging of the National Institutes of Health for the project, "Octopamine mediates benefits of endurance exercise in Drosophila."

30 Jun 2017

UA researcher’s findings on estrogen may lead to promising treatment for hot flashes

Fifteen years ago, Dr. Naomi Rance was at work when she experienced her first hot flash. Rance, a physician and researcher at the University of Arizona College of Medicine - Tucson, took note.

29 Jun 2017

Elevated levels of suPAR protein combine with genetic mutation to trigger CKD in black people

Between 15 and 20 percent of black people carry a genetic mutation that puts them at risk for certain chronic kidney disease, but only about half of them develop the illness – a variance that long has puzzled researchers.

27 Jun 2017

New monoclonal antibody shows efficacy in chronic migraine patients with medication overuse

A new human antibody may soon become available as a specific medication for preventing frequent migraine attacks.

27 Jun 2017

Study offers insight into earliest molecular steps that lead to organ rejection

Researchers at the University of Pittsburgh School of Medicine and the University of Toronto have uncovered the first molecular steps that lead to immune system activation and eventual rejection of a transplanted organ.

23 Jun 2017

Research provides insights into how light may interact with the brain to affect sleep

Humans are diurnal animals, meaning that we usually sleep at night and are awake during the day, due at least in part to light or the lack thereof. Light is known to affect sleep indirectly by entraining--modifying the length of--our circadian rhythms and also rapidly and directly due to a phenomenon known as masking.

23 Jun 2017

Japanese scientists show how male pheromone enhances female sexual behavior in mice

A study by a group of Japanese scientists showed how a male pheromone in mice enhances sexual behaviors in females--and how it may enhance a different behavior, aggression, in males -- by identifying distinct neural circuits and neurons that generate a particular behavioral response to specific chemical signals.

22 Jun 2017

Researchers identify key protein that helps trigger ketamine's rapid antidepressant effects

UT Southwestern Medical Center scientists have identified a key protein that helps trigger ketamine's rapid antidepressant effects in the brain, a crucial step to developing alternative treatments to the controversial drug being dispensed in a growing number of clinics across the country.

22 Jun 2017

Scientists develop new algorithm to decipher how immune system recognizes and binds antigens

Scientists from St. Jude Children's Research Hospital and Fred Hutchinson Cancer Research Center have developed an algorithm that functions like a Rosetta Stone to help decipher how the immune system recognizes and binds antigens.

22 Jun 2017

Review highlights effective treatment options for managing patients with T2D and osteoporosis

Type 2 diabetes (T2D) and osteoporosis often coexist in patients, but managing both conditions can be a challenge.

21 Jun 2017

Discovery of ‘protective shield’ for b-cells could provide new option for treating diabetes

The islets of Langerhans in the human pancreas produce and release insulin to regulate blood glucose levels. Insulin, which is specifically produced in b-cells, serves to prompt cells to take up glucose circulating in blood.

21 Jun 2017

Finnish researchers find accumulation of gene mutations in some patients with rheumatoid arthritis

Gene mutations accumulating in cells are typical of the development of cancer. Finnish researchers found that a similar accumulation of mutations occurs also in some patients with rheumatoid arthritis.

21 Jun 2017

Mutations identified that enable human transmission of avian flu

A systematic mutation analysis has shown that changes in just three amino acids of the avian influenza H7N9 virus receptor binding protein confers specificity for human cells.

16 Jun 2017

Targeting regulatory T cells could be effective approach to treating cancers, research shows

Researchers at University of Pittsburgh School of Medicine and UPMC have discovered a clue that could unlock the potential of immunotherapy drugs to successfully treat more cancers.

15 Jun 2017

Researchers bioengineer human liver tissues that mimic natural development

An international team of researchers bioengineering human liver tissues uncovered previously unknown networks of genetic-molecular crosstalk that control the organ's developmental processes – greatly advancing efforts to generate healthy and usable human liver tissue from human pluripotent stem cells.

15 Jun 2017

New TSRI study could have implications for development of flu vaccines, drug therapies

Scientists at The Scripps Research Institute have shown that for the virus that causes the flu, two wrongs can sometimes make a right.

15 Jun 2017

Scientists uncover mechanism that directly links inflammation to mental illness

Up to 75 percent of patients with systemic lupus erythematosus -- an incurable autoimmune disease commonly known as lupus -- experience neuropsychiatric symptoms.

14 Jun 2017

SLU scientists discover nuclear receptor that appears to play key role in muscle regeneration

Saint Louis University researchers report in Molecular Metabolism new findings that the nuclear receptor REV-ERB appears to play a key role in muscle regeneration, suggesting the receptor may be a good target for new drugs to treat a variety of muscle disorders and injuries.

14 Jun 2017

Researchers explore impact of hair products on breast cancer risk

Can use of hair products have an impact on breast cancer risk for women? That is a question explored by Rutgers University investigators – and colleagues from Roswell Park Cancer Institute, Massachusetts General Hospital and Moffitt Cancer Center.

14 Jun 2017

Receptor News and Research

Scientists identify neurons that play crucial roles in connecting emotions and sleep

Wayne State researchers receive NIH grant to mimic benefits of exercise in sedentary patients

UA researcher’s findings on estrogen may lead to promising treatment for hot flashes

Elevated levels of suPAR protein combine with genetic mutation to trigger CKD in black people

New monoclonal antibody shows efficacy in chronic migraine patients with medication overuse

Study offers insight into earliest molecular steps that lead to organ rejection

Research provides insights into how light may interact with the brain to affect sleep

Japanese scientists show how male pheromone enhances female sexual behavior in mice

Researchers identify key protein that helps trigger ketamine's rapid antidepressant effects

Scientists develop new algorithm to decipher how immune system recognizes and binds antigens

Review highlights effective treatment options for managing patients with T2D and osteoporosis

Discovery of ‘protective shield’ for b-cells could provide new option for treating diabetes

Finnish researchers find accumulation of gene mutations in some patients with rheumatoid arthritis

Mutations identified that enable human transmission of avian flu

Targeting regulatory T cells could be effective approach to treating cancers, research shows

Researchers bioengineer human liver tissues that mimic natural development

New TSRI study could have implications for development of flu vaccines, drug therapies

Scientists uncover mechanism that directly links inflammation to mental illness

SLU scientists discover nuclear receptor that appears to play key role in muscle regeneration

Researchers explore impact of hair products on breast cancer risk

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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