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Direct contact with lymphatic endothelial cells promotes melanoma metastasis

Despite the declining death rates for many individual cancer types, mortality for a few cancers has stabilized or even increased. One of these is melanoma due to its ability, in later stages, to spread to other parts of the body.

2 May 2018

New T cell biomarker could be much-needed patient-selection tool for CAR T cell therapy

Penn Medicine researchers may have found the reason why some patients with advanced chronic lymphocytic leukemia don't respond to chimeric antigen receptor T cell therapy, and the answer is tied to how primed patients' immune systems are before the therapy is administered.

30 Apr 2018

Auditory brainstem implant helps patients with neurofibromatosis type 2

Patients with rare brain tumors on the auditory nerve now have an option to prevent complete deafness at UC San Diego Health. The device, called an auditory brainstem implant or ABI, fits behind the ear and connects directly to the brainstem.

30 Apr 2018

New pill for breast cancer diagnosis could do a better job than mammograms

As many as one in three women treated for breast cancer undergo unnecessary procedures, but a new method for diagnosing it could do a better job distinguishing between benign and aggressive tumors.

30 Apr 2018

Researchers show how Spred1 molecule protects HSC homeostasis under diet-induced stress

Researchers at Kanazawa University report in Cell Stem Cell how the Spred1 molecule is involved in hematopoietic stem cell self-renewal. Experiments with mouse models show that under normal conditions, Spred1 acts as a negative regulator, while under diet-induced stress, it protects hematopoietic homeostasis.

28 Apr 2018

New results reinforce COPAXONE 40 mg/mL as safe and effective for RMS patients

Teva Pharmaceutical Industries Ltd., today announced up to 7-year efficacy, safety and tolerability results from the Glatiramer Acetate Low-Frequency Administration (GALA) open-label extension study of COPAXONE (glatiramer acetate injection) 40 mg/mL administered subcutaneously three-times-a-week for the treatment of relapsing forms of multiple sclerosis (RMS).

28 Apr 2018

Pioneering study could be a step closer to finding the most effective way to treat cancer

Doctors could be a step closer to finding the most effective way to treat cancer with a double whammy of a virus combined with boosting the natural immune system, according to a pioneering study by researchers at The University of Texas Health Science Center at Houston (UTHealth) and The Ohio State University.

27 Apr 2018

Researchers recommend anti-cancer immunotherapies for treatment of thyroid cancer

University of Colorado Cancer Center researchers recently completed the largest-ever study of thyroid cancer genetics, mining the data of 583 patient samples of advanced differentiated thyroid cancer and 196 anaplastic thyroid cancers.

27 Apr 2018

Blood biopsies may offer more comprehensive genetic information than bone marrow tests, shows research

Bone marrow biopsies are the gold standard for diagnosing and monitoring the progression of multiple myeloma, but these procedures are far too invasive to perform at every patient visit.

27 Apr 2018

Plants provide a new avenue in curbing tumor growth

Plants have provided a new avenue in curbing tumor growth. On this occasion, it doesn't involve miracle species or the like, but rather the results obtained by the University of Cordoba BIO301 research team called "Epigenetics and DNA Repair."

27 Apr 2018

Specific type of RNA editing plays key role in protein variation in cancer cells, shows research

A multi-center study led by The University of Texas MD Anderson Cancer Center has shed light on why proteins, the seedlings that serve as the incubator for many cancers, can vary from cancer to cancer and even patient to patient, a discovery that adds to a growing base of knowledge important for developing more effective precision therapies.

27 Apr 2018

New CAR-T therapy could provide safer, more effective cancer treatment

There have been few cancer treatments with such a promising future as using the patient's own immune system.

27 Apr 2018

Zika virus can be used for treating aggressive human central nervous system tumors, shows study

A Brazilian study published April 26 in the journal Cancer Research shows for the first time in vivo that Zika virus can be used as a tool to treat aggressive human central nervous system (CNS) tumors.

27 Apr 2018

Common therapy options for psoriasis can help reduce coronary plaque, study shows

Late-breaking clinical science shows common therapy options for psoriasis (PSO)-a chronic inflammatory skin disease-can help reduce coronary plaque. The authors found that not only do the treatments reduce the volume of the plaque, but also the plaque becomes less inflammatory over time harboring fewer characteristics prone to rupture and cause a heart attack.

26 Apr 2018

Detailed genetic testing of head and neck cancers could lead to more personalized treatments

Research led by UNC School of Medicine student Wesley Stepp, PhD, shows how more detailed genetic testing of head and neck tumors could lead to more personalized treatments for patients.

26 Apr 2018

Scientists work on erasable MRI contrast agents that can blink off on command

Magnetic resonance imaging, or MRI, is a widely used medical tool for taking pictures of the insides of our body.

26 Apr 2018

New noninvasive technique uses blood test to detect brain tumor biomarkers

Taking a biopsy of a brain tumor is a complicated and invasive surgical process, but a team of researchers at Washington University in St. Louis is developing a way that allows them to detect tumor biomarkers through a simple blood test.

26 Apr 2018

Researchers uncover how obesity leads to cancer in epithelial cells

A new study led by researchers at Hokkaido University has shown that obesity may enhance the progression of cancer, while aspirin may protect against it.

26 Apr 2018

‘Rapid autopsy’ programs seek clues to cancer within hours of death

After Keith Beck died of bile duct cancer last year, family members said more than 900 people showed up to pay respects to the popular athletic director at the University of Findlay in northwestern Ohio.

26 Apr 2018

Researchers target telomerase for killing NRAS-mutant melanoma cells

Targeting telomerase was effective at killing NRAS-mutant melanoma cells, and the impact was further enhanced when the strategy was paired with an inhibitor of mitochondrial function, according to study results by The Wistar Institute published in Oncogene.

26 Apr 2018

Tumor News and Research

Direct contact with lymphatic endothelial cells promotes melanoma metastasis

New T cell biomarker could be much-needed patient-selection tool for CAR T cell therapy

Auditory brainstem implant helps patients with neurofibromatosis type 2

New pill for breast cancer diagnosis could do a better job than mammograms

Researchers show how Spred1 molecule protects HSC homeostasis under diet-induced stress

New results reinforce COPAXONE 40 mg/mL as safe and effective for RMS patients

Pioneering study could be a step closer to finding the most effective way to treat cancer

Researchers recommend anti-cancer immunotherapies for treatment of thyroid cancer

Blood biopsies may offer more comprehensive genetic information than bone marrow tests, shows research

Plants provide a new avenue in curbing tumor growth

Specific type of RNA editing plays key role in protein variation in cancer cells, shows research

New CAR-T therapy could provide safer, more effective cancer treatment

Zika virus can be used for treating aggressive human central nervous system tumors, shows study

Common therapy options for psoriasis can help reduce coronary plaque, study shows

Detailed genetic testing of head and neck cancers could lead to more personalized treatments

Scientists work on erasable MRI contrast agents that can blink off on command

New noninvasive technique uses blood test to detect brain tumor biomarkers

Researchers uncover how obesity leads to cancer in epithelial cells

‘Rapid autopsy’ programs seek clues to cancer within hours of death

Researchers target telomerase for killing NRAS-mutant melanoma cells

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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