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New insights on the circadian clock of Drosophila melanogaster

The higher the temperatures, the faster physiological processes are. But there is an exception: the so-called circadian clock, which regulates the sleep-wake cycle in organisms.

30 Dec 2022

New insights into how working memory information may be held in mind

Between the time you read the Wi-Fi password off the café's menu board and the time you can get back to your laptop to enter it, you have to hold it in mind.

29 Dec 2022

Human cortical organoids implanted in mice establish functional connectivity and respond to sensory stimuli

A team of engineers and neuroscientists has demonstrated for the first time that human brain organoids implanted in mice have established functional connectivity to the animals' cortex and responded to external sensory stimuli.

29 Dec 2022

Horizontal gene transfer from mother to infant influences gut microbiome assembly, neurodevelopment, and immune maturation in infants

Researchers used a multi-omics approach to profile the gut microbiomes and metabolomes of mothers and infants to determine the vertical and horizontal transmission of bacterial species and strains as well as individual genes and understand the dynamics of the gut microbiome assembly that shape the development of the infant before and after birth.

29 Dec 2022

Study investigates a new mechanism of pyrethroid derivatives-moderated programmed cell death

A new research paper was published in Oncotarget's Volume 13 on December 17, 2022, entitled, "The role of pyrethroid derivatives in autophagy and apoptosis crosstalk signaling and potential risk for malignancies."

29 Dec 2022

Unraveling the biology of senescent cells and healthy aging

Multiple researchers at the Jackson Laboratory are taking part in an ambitious research program spanning several top research institutions to study senescent cells.

29 Dec 2022

Sarunashi juice and its constituting component help prevent and reduce lung cancer in mice

Lung cancer is the leading cause of death in Japan and across the globe. Among all the cancers, lung cancer has one of the lowest five-year survival rates.

28 Dec 2022

Researchers unravel how cells use their sense of touch to make decisions during embryogenesis

A research team at the Cluster of Excellence Physics of Life of TU Dresden and the University of California, Santa Barbara, reveals how cells sense their mechanical environment as they build tissues during embryogenesis.

28 Dec 2022

Enzyme that defends human cells against viruses may be a potential target for future cancer treatments

An enzyme that defends human cells against viruses can help drive cancer evolution towards greater malignancy by causing myriad mutations in cancer cells, according to a study led by investigators at Weill Cornell Medicine.

28 Dec 2022

New mathematical model for the motion of bacteria

Biofilms form when microorganisms such as certain types of bacteria adhere to the surface of objects in a moist environment and begin to reproduce resulting in the excretion of a slimy glue-like substance.

28 Dec 2022

Study reveals a previously unappreciated complexity of TRM cell biology in the gut

Recent pressure to maximize vaccine efficacy has stirred up many new discoveries within immunology, revealing numerous paradigms with untapped therapeutic potential.

28 Dec 2022

Alveolar macrophages present as antigens to promote virus-specific CD8+ T cell expansion

The human immune system is a highly complex network of cells, signals, and responses that is tightly regulated to ensure that the body can fight off infection without damaging its own tissues.

28 Dec 2022

How could probiotics be used in the management of gingivitis and periodontitis?

New research explores how probiotic-based therapy in conjunction with established treatment regimens can be an effective approach for combating gingivitis and periodontitis.

28 Dec 2022

Exploring T cell responses during COVID-19 breakthrough infection

Researchers assessed the de novo and recall T cell responses during coronavirus disease 2019 (COVID-19) breakthrough infection.

28 Dec 2022

Scientists gain new insights into the opposing actions of serotonin-producing nerve fibers in mice

New insights into the opposing actions of serotonin-producing nerve fibers in mice could lead to drugs for treating addictions and major depression.

28 Dec 2022

Scientists explore synthesis of griffithsin in cell-free systems

A new study described the cell-free manufacturing of griffithsin (GRFT), a broad-spectrum antiviral protein.

28 Dec 2022

New test detects biomarker of Alzheimer's disease neurodegeneration in blood samples

A group of neuroscientists led by a University of Pittsburgh School of Medicine researcher developed a test to detect a novel marker of Alzheimer's disease neurodegeneration in a blood sample. A study on their results was published today in Brain.

28 Dec 2022

SHEA advises against COVID screening of asymptomatic patients

Society for Healthcare Epidemiology of America says layers of protection are more effective and have fewer unintended harms

27 Dec 2022

Scientists find key reason for ongoing loss of smell in long-COVID

In a recent study published in the journal Science Translational Medicine, researchers reported that long-term anosmia following coronavirus disease 2019 (COVID-19) could be a result of persistent T-cell mediated inflammation occurring in the olfactory epithelium even after the elimination of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from the olfactory tissue.

27 Dec 2022

Insilico announces nomination of preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy

Insilico Medicine ("Insilico"), a clinical-stage end-to-end artificial intelligence (AI)-driven drug discovery company, today announced that the company's drug discovery team has nominated a preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy utilizing its end-to-end Pharma.AI platform.

27 Dec 2022

B Cell News and Research

New insights on the circadian clock of Drosophila melanogaster

New insights into how working memory information may be held in mind

Human cortical organoids implanted in mice establish functional connectivity and respond to sensory stimuli

Horizontal gene transfer from mother to infant influences gut microbiome assembly, neurodevelopment, and immune maturation in infants

Study investigates a new mechanism of pyrethroid derivatives-moderated programmed cell death

Unraveling the biology of senescent cells and healthy aging

Sarunashi juice and its constituting component help prevent and reduce lung cancer in mice

Researchers unravel how cells use their sense of touch to make decisions during embryogenesis

Enzyme that defends human cells against viruses may be a potential target for future cancer treatments

New mathematical model for the motion of bacteria

Study reveals a previously unappreciated complexity of TRM cell biology in the gut

Alveolar macrophages present as antigens to promote virus-specific CD8+ T cell expansion

How could probiotics be used in the management of gingivitis and periodontitis?

Exploring T cell responses during COVID-19 breakthrough infection

Scientists gain new insights into the opposing actions of serotonin-producing nerve fibers in mice

Scientists explore synthesis of griffithsin in cell-free systems

New test detects biomarker of Alzheimer's disease neurodegeneration in blood samples

SHEA advises against COVID screening of asymptomatic patients

Scientists find key reason for ongoing loss of smell in long-COVID

Insilico announces nomination of preclinical candidate targeting KAT6A for ER+/HER2- breast cancer therapy

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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