Receptor News and Research

RSS

Seattle Children’s opens first clinical trial to study IBD and GVHD in pediatric patients

In an effort to find new strategies to personalize treatment for pediatric patients, Seattle Children's has opened the first clinical trial applying next-generation T-cell receptor sequencing and single-cell gene expression analysis to better understand how the immune system drives both inflammatory bowel disease in pediatric autoimmunity patients and graft-versus host disease in pediatric bone marrow transplant patients.

From 10x Genomics, Inc. 23 May 2017

Research uncovers role of gut microbiota in anti-obesity effects of dietary capsaicin

Scientists have discovered a dietary strategy that may address obesity by reducing endotoxemia, a major contributor to chronic, low-grade inflammation (CLGI).

23 May 2017

Study describes novel T cell population that recognizes and kills tumor cells

Scientists at the University of Basel in Switzerland have, for the first time, described a new T cell population that can recognize and kill tumor cells. The open access journal eLife has published the results.

23 May 2017

Physically active lifestyle, limiting alcohol could help lower breast cancer risk

Drinking just one glass of wine or other alcoholic drink a day increases breast cancer risk, finds a major new report by the American Institute for Cancer Research and the World Cancer Research Fund.

23 May 2017

Investigational biologic may reduce need for systemic corticosteroids in patients with severe asthma

An investigational biologic may reduce the need for adults with severe asthma to take an oral corticosteroid to control their asthma, according to a randomized controlled trial presented at the ATS 2017 International Conference.

22 May 2017

Complex malaria vaccine protects monkeys against virulent parasite strains

Researchers from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, modified an experimental malaria vaccine and showed that it completely protected four of eight monkeys that received it against challenge with the virulent Plasmodium falciparum malaria parasite.

22 May 2017

Study identifies two T cell biomarkers that may predict survival trajectory of IPF patients

Two T cell biomarkers appear to predict the survival trajectory of patients with idiopathic pulmonary fibrosis (IPF), a lung disease that has a varied, but ultimately devastating, impact on patients, according to new research presented at the ATS 2017 International Conference.

22 May 2017

Scientists to develop drugs for treating cognitive deficits in Huntington's disease sufferers

Scientists at the University of Sussex have started work on a multi-million pound project to develop drugs to treat the debilitating loss of cognitive function associated with Huntington's disease.

19 May 2017

Researchers show how cancer therapy works in different way to destroy tumor cells

Antibodies to the proteins PD-1 and PD-L1 have been shown to fight cancer by unleashing the body's T cells, a type of immune cell.

18 May 2017

IBS scientists uncover biological pathway that contributes to thyroid disorder

A team led by KOH Gou Young, director of the Center for Vascular Research, within the Institute for Basic Science, in collaboration with Chungnam National University, clarified the molecular mechanism to explain how the thyroid and surrounding vascular system change in the most common form of hyperthyroidism.

18 May 2017

Research paves way for safer and more effective drugs to treat type 2 diabetes

Research led by the University of Adelaide is paving the way for safer and more effective drugs to treat type 2 diabetes, reducing side effects and the need for insulin injections.

18 May 2017

Targeted therapy appears to be more effective in preventing lung cancer recurrence

The targeted therapy gefitinib appears more effective in preventing recurrence after lung cancer surgery than the standard of care, chemotherapy.

18 May 2017

University of Guelph researcher discovers effective way to treat shortness of breath in heart failure

Shortness of breath is the No.1 complaint of people suffering from heart failure. Now a University of Guelph researcher has discovered its surprising cause - and an effective treatment - in a groundbreaking new study.

17 May 2017

Scientists unravel mystery of T cell signaling process vital to immune response

The immune system cells known as T cells play a central role in the body's ability to fight infections and cancer. For decades, however, details of the molecular signaling process that leads to T cell activation have remained a mystery.

16 May 2017

Discovery of steroid hormone in fruit flies may shed new light on maternal hypothyroidism

University of Oregon researchers using Drosophila have identified a steroid hormone that triggers a vital transition in early brain development in which neural stem cells properly change gears to produce different kinds of neurons.

15 May 2017

Study findings could pave way for better drugs to fight against parasitic infections

Immune cells, called macrophages, may rely on a compound to signal an attack to beat back attacks from parasitic worms, according to an international team of researchers, including Zissis C. Chroneos, associate professor of pediatrics, and microbiology and immunology at Penn State College of Medicine.

12 May 2017

Receptor News and Research

Seattle Children’s opens first clinical trial to study IBD and GVHD in pediatric patients

Research uncovers role of gut microbiota in anti-obesity effects of dietary capsaicin

Study describes novel T cell population that recognizes and kills tumor cells

Physically active lifestyle, limiting alcohol could help lower breast cancer risk

Investigational biologic may reduce need for systemic corticosteroids in patients with severe asthma

Complex malaria vaccine protects monkeys against virulent parasite strains

Study identifies two T cell biomarkers that may predict survival trajectory of IPF patients

Scientists to develop drugs for treating cognitive deficits in Huntington's disease sufferers

Researchers show how cancer therapy works in different way to destroy tumor cells

IBS scientists uncover biological pathway that contributes to thyroid disorder

Research paves way for safer and more effective drugs to treat type 2 diabetes

Targeted therapy appears to be more effective in preventing lung cancer recurrence

University of Guelph researcher discovers effective way to treat shortness of breath in heart failure

Scientists unravel mystery of T cell signaling process vital to immune response

Discovery of steroid hormone in fruit flies may shed new light on maternal hypothyroidism

Study findings could pave way for better drugs to fight against parasitic infections

Scientists reveal how immune cells activate to kill parasitic worms

Suppression of thyroid hormone receptor protects cone cells in mouse models of retinal diseases

Rat study reveals new treatment approach that could potentially prevent osteoarthritis

Breast cancer drug offers protection against obesity-related metabolic disorders

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News