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Study provides new understanding of molecular mechanisms that impact intellectual disability

Scientists from the Florida campus of The Scripps Research Institute have shown that a protein helps balance nerve cell communication.

25 Apr 2017

Novel mechanism of antidepressant action may benefit patients unresponsive to SSRI treatment

Antidepressants treat symptoms of depression by increasing levels of brain signaling molecules such as serotonin, as with the most widely used type of antidepressant, selective serotonin reuptake inhibitors.

25 Apr 2017

Combination of genetics and experience gives each individual a unique sense of smell, study finds

Researchers from the Wellcome Trust Sanger Institute and their collaborators have shown that receptors in the noses of mice exposed to certain smells during life are different to genetically similar mice that lived without those smells.

25 Apr 2017

Synthetic scaffold loaded with cancer-fighting T cells effectively shrinks solid tumors

Cellular therapy hasn't had much success in fighting solid tumors, partly because it's been difficult to deliver anti-cancer T cells to the tumors.

25 Apr 2017

Brain genes influence our eating habits, study finds

Differences in the genetic make-up of our brains may account for the particular food preferences people have and their varying ability to stick to diets, according to new research.

24 Apr 2017

Study shows how brain genes influence food intake and dietary preferences

Have you ever wondered why you keep eating certain foods, even if you know they are not good for you? Gene variants that affect the way our brain works may be the reason, according to a new study. The new research could lead to new strategies to empower people to enjoy and stick to their optimal diets.

24 Apr 2017

Johns Hopkins researchers discover group of nerve cells in the skin responsible for ‘active touch’

Working with genetically engineered mice -- and especially their whiskers -- Johns Hopkins researchers report they have identified a group of nerve cells in the skin responsible for what they call "active touch," a combination of motion and sensory feeling needed to navigate the external world.

21 Apr 2017

Researchers discover how protein aggregation triggers aging

Not only does our way of life determine how long we live but so too does our genetic material. Of particular importance here is a genetic program that is controlled by the insulin receptor. A team of researchers from the Universities of Cologne and Bonn has now discovered how protein aggregation affects this genetic program and thus triggers aging.

21 Apr 2017

‘Geneva signature’ evaluates safety and immunogenicity of promising anti-Ebola virus vaccine

An international team based at Geneva University Hospitals and at the University of Geneva, Switzerland, has succeeded in defining a "signature" composed of a small number of inflammatory markers that can be monitored in order to understand how a promising anti-Ebola virus vaccine stimulates the immune system.

19 Apr 2017

Researchers develop prognostic tool that predicts risk of kidney failure in diabetes patients

Researchers from Joslin Diabetes Center have developed a prognostic tool that accurately predicts the risk of end stage renal disease (ESRD) in patients with both type 1 and type 2 diabetes.

18 Apr 2017

Cytokine plays critical role in driving immune cells to promote or suppress inflammatory bowel disease

A certain cytokine, or small protein that helps cells communicate during immune responses, can control whether immune cells promote or suppress inflammatory bowel disease, a finding that could lead to new treatments, according to a study led by Georgia State University.

18 Apr 2017

Atomic resolution structure of key molecule may contribute to drug discovery for devastating conditions

Culminating a nearly 10 year effort, researchers have determined the atomic resolution structure of a key molecule that translates signals from a cell's local environment into a language that the cell can understand and use.

18 Apr 2017

TSRI study could lead to personalized treatments for alcohol dependence

A new study led by scientists at The Scripps Research Institute could help researchers develop personalized treatments for alcoholism and alcohol use disorder.

12 Apr 2017

Developmental Split-Brain syndrome discovery

Our group describes a new entity, which we refer to as “Developmental Split-Brain syndrome” which we discovered affected four individuals from three unrelated families. All affected individuals showed disruption of communicating tracts between the right and left side of the brain which meant that there is lack of coordination and communication between the two sides of the brain.

12 Apr 2017

Transmembrane protein complexes shed light on antibiotic resistance in bacteria

An international team including researchers from MIPT’s Laboratory for Advanced Studies of Membrane Proteins have proposed an explanation of the way bacteria process external signals.

12 Apr 2017

TSRI scientists find new way to make cell population resistant to HIV

Scientists at The Scripps Research Institute have found a way to tether HIV-fighting antibodies to immune cells, creating a cell population resistant to the virus.

11 Apr 2017

Researchers design first light-activated drug for treatment of pain

A team of the Institute of Neurosciences of the University of Barcelona has participated in the design of the first light-activated drug -the JF-NP-26, for the treatment of pain, according to a research with animal models published in the journal eLife.

11 Apr 2017

Scientists discover new role for autophagosomes in neurodegenerative diseases

Autophagosomes are at the center of attention, at least since the Nobel Prize for Medicine was awarded for research on autophagy in 2016. The much talked about autophagosomes are small membrane vesicles in charge of waste disposal to promote recycling of its components.

11 Apr 2017

Study identifies key mediator in learning process

The ability of the brain to respond and adapt to changes is scientifically called brain plasticity. This ability is the basis of all learning processes.

7 Apr 2017

Researchers uncover critical pathway that helps pancreatic cancer cells turn off immune system

Researchers at NYU Langone Medical Center and its Perlmutter Cancer Center have uncovered a critical pathway by which pancreatic cancer cells turn off the immune system charged with attacking them. The findings appear in a paper published online in Nature Medicine April 10.

7 Apr 2017

Receptor News and Research

Study provides new understanding of molecular mechanisms that impact intellectual disability

Novel mechanism of antidepressant action may benefit patients unresponsive to SSRI treatment

Combination of genetics and experience gives each individual a unique sense of smell, study finds

Synthetic scaffold loaded with cancer-fighting T cells effectively shrinks solid tumors

Brain genes influence our eating habits, study finds

Study shows how brain genes influence food intake and dietary preferences

Johns Hopkins researchers discover group of nerve cells in the skin responsible for ‘active touch’

Researchers discover how protein aggregation triggers aging

‘Geneva signature’ evaluates safety and immunogenicity of promising anti-Ebola virus vaccine

Researchers develop prognostic tool that predicts risk of kidney failure in diabetes patients

Cytokine plays critical role in driving immune cells to promote or suppress inflammatory bowel disease

Atomic resolution structure of key molecule may contribute to drug discovery for devastating conditions

TSRI study could lead to personalized treatments for alcohol dependence

Developmental Split-Brain syndrome discovery

Transmembrane protein complexes shed light on antibiotic resistance in bacteria

TSRI scientists find new way to make cell population resistant to HIV

Researchers design first light-activated drug for treatment of pain

Scientists discover new role for autophagosomes in neurodegenerative diseases

Study identifies key mediator in learning process

Researchers uncover critical pathway that helps pancreatic cancer cells turn off immune system

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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