Paralysis News and Research

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Paralysis is the loss of muscle function in part of your body. It happens when something goes wrong with the way messages pass between your brain and muscles. Paralysis can be complete or partial. It can occur on one or both sides of your body. It can also occur in just one area, or it can be widespread. Paralysis of the lower half of your body, including both legs, is called paraplegia. Paralysis of the arms and legs is quadriplegia.

Research to help patients suffering from severe spinal cord injuries

Many patients suffer from severe spinal cord injuries after being involved in traffic accidents or accidents at work.

5 Sep 2014

Janssen, Bayer announce expansion of EXPLORER global cardiovascular research program for XARELTO

Janssen Research & Development, LLC and its development partner, Bayer HealthCare, announced today the expansion of the EXPLORER global cardiovascular research program for XARELTO (rivaroxaban) to include additional high-risk patient populations.

29 Aug 2014

Asterias receives clearance from FDA to initiate Phase 1/2a clinical trial of AST-OPC1

Asterias Biotherapeutics Inc. has received clearance from the U.S. Food and Drug Administration to initiate a Phase 1/2a clinical trial of its product, AST-OPC1, in patients with complete cervical spinal cord injury.

27 Aug 2014

Mylan launches Potassium Chloride Extended-release Tablets

Mylan Inc. today announced that it has launched Potassium Chloride Extended-release Tablets USP, 8 mEq (600 mg) and 10 mEq (750 mg), which is the generic version of Upsher-Smith's Klor-Con.

22 Aug 2014

Blocking nerve signals could be effective treatment for stomach cancer

Research from Columbia University Medical Center shows that nerves may play a critical role in stomach cancer growth and that blocking nerve signals using surgery or Botox® (onabotulinumtoxinA) could be an effective treatment for the disease.

21 Aug 2014

ALS Association surpasses $10 million in "Ice Bucket" donations

Today, The ALS Association announced it has surpassed $10 million in "Ice Bucket" donations. Specifically, as of Saturday, August 16, 2014, The ALS Association has received $11.4 million in donations compared to $1.7 million during the same time period last year (July 29 to August 16).

17 Aug 2014

FDA approves BELSOMRA® (suvorexant) for the treatment of insomnia

Merck (NYSE: MRK), known as MSD outside the United States and Canada, announced today that the U.S. Food and Drug Administration (FDA) has approved BELSOMRA® (suvorexant) for adults with insomnia who have difficulty falling asleep and/or staying asleep. BELSOMRA (pronounced bell-SOM-rah) is a highly selective antagonist for orexin receptors.

15 Aug 2014

ALS Association awards 21 new research grants to find cure for amyotrophic lateral sclerosis

The ALS Association announced today that it has awarded 21 new research grants totaling nearly $3.5 million to find treatments and a cure for amyotrophic lateral sclerosis (ALS). The grants were awarded to scientists from laboratories located in nine different states in the United States as well as from the United Kingdom, France, Canada, Switzerland, Israel and Australia.

11 Aug 2014

Neurons derived from human iPSC and grafted into rats after spinal cord injury produce cells

Building upon previous research, scientists at the University of California, San Diego School of Medicine and Veteran's Affairs San Diego Healthcare System report that neurons derived from human induced pluripotent stem cells (iPSC) and grafted into rats after a spinal cord injury produced cells with tens of thousands of axons extending virtually the entire length of the animals' central nervous system.

8 Aug 2014

Small molecule may be able to convince damaged nerves to effectively rewire circuits

Frogs, dogs, whales, snails can all do it, but humans and primates can't. Regrow nerves after an injury, that is—while many animals have this ability, humans don't.

6 Aug 2014

Lack of reporting standards delays progress in developing robust therapies for SCI, TBI

Progress in developing robust therapies for spinal cord injury (SCI), traumatic brain injury (TBI) and peripheral nerve injury has been slow.

31 Jul 2014

Study reveals new invasion mechanism of Enterovirus 71

A new study determines glycosylation and pH-dependent conformational changes of virus receptor SCARB2 as crucial for EV71 attachment, entry and uncoating.

21 Jul 2014

Genervon generates biomarker data for its Phase 2a clinical trial for ALS

Genervon Biopharmaceuticals LLC ("Genervon") today announced that it has analyzed and generated a Biomarker Data Report for its recent Phase 2a clinical trial for ALS disease modification.

30 Jun 2014

Amyotrophic lateral sclerosis in veterans: an interview with Milan Michael Karol, The Robert Packard Center for ALS Research at Johns Hopkins

ALS stands for Amyotrophic Lateral Sclerosis, better known as “Lou Gehrig’s Disease”. It is a progressive neurodegenerative disease characterized by the death of motor neurons in the brain and spinal cord.

30 Jun 2014

Increasing clearance of ALS misfolded protein from neurons improves their survival

In work supported by The ALS Association, researchers have shown that increasing the clearance of misfolded protein from neurons improves their survival. The study was published today in the journal Nature Chemical Biology.

30 Jun 2014

FDA approves marketing of first motorized device for patients with spinal cord injuries

The U.S. Food and Drug Administration today allowed marketing of the first motorized device intended to act as an exoskeleton for people with lower body paralysis (paraplegia) due to a spinal cord injury.

27 Jun 2014

International leaders redefine phenotypes of multiple sclerosis

Multiple sclerosis manifests itself in many different ways and different courses. A recent effort to fine-tune descriptions - or phenotypes -- of MS was undertaken by an international team of leaders in MS research and clinical care.

9 Jun 2014

Viewpoints: Michelle Obama and school lunches; more about the VA health system 'scandal'; context and caution on Medicare's physician data release

When we began our Let's Move! initiative four years ago, we set one simple but ambitious goal: to end the epidemic of childhood obesity in a generation so that kids born today will grow up healthy.

30 May 2014

Researchers take another promising step toward developing universal antidote for snakebite

A team of researchers, led by Dr. Matthew Lewin of the California Academy of Sciences and Dr. Stephen P. Samuel of Trinity College Dublin, Ireland has taken another promising step toward developing a universal antidote for snakebite.

29 May 2014

New report raises important questions about transcranial direct current stimulation

Over the past several decades, neurostimulation techniques such as transcranial direct current stimulation (tDCS) have gradually gained favour in the public eye. In a new report, published yesterday in the prestigious scientific journal Neuron, IRCM ethics experts raise important questions about the rising tide of tDCS coverage in the media, while regulatory action is lacking and ethical issues need to be addressed.

23 May 2014

Paralysis News and Research

Further Reading

Research to help patients suffering from severe spinal cord injuries

Janssen, Bayer announce expansion of EXPLORER global cardiovascular research program for XARELTO

Asterias receives clearance from FDA to initiate Phase 1/2a clinical trial of AST-OPC1

Mylan launches Potassium Chloride Extended-release Tablets

Blocking nerve signals could be effective treatment for stomach cancer

ALS Association surpasses $10 million in "Ice Bucket" donations

FDA approves BELSOMRA® (suvorexant) for the treatment of insomnia

ALS Association awards 21 new research grants to find cure for amyotrophic lateral sclerosis

Neurons derived from human iPSC and grafted into rats after spinal cord injury produce cells

Small molecule may be able to convince damaged nerves to effectively rewire circuits

Lack of reporting standards delays progress in developing robust therapies for SCI, TBI

Study reveals new invasion mechanism of Enterovirus 71

Genervon generates biomarker data for its Phase 2a clinical trial for ALS

Amyotrophic lateral sclerosis in veterans: an interview with Milan Michael Karol, The Robert Packard Center for ALS Research at Johns Hopkins

Increasing clearance of ALS misfolded protein from neurons improves their survival

FDA approves marketing of first motorized device for patients with spinal cord injuries

International leaders redefine phenotypes of multiple sclerosis

Viewpoints: Michelle Obama and school lunches; more about the VA health system 'scandal'; context and caution on Medicare's physician data release

Researchers take another promising step toward developing universal antidote for snakebite

New report raises important questions about transcranial direct current stimulation

Industry Focus eBook - Cell biology (5th edition) eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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