Progenitor Cells News and Research

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Scientists find a way to rapidly produce pure populations of oligodendrocyte progenitor cells

Scientists at Case Western Reserve University School of Medicine found a way to rapidly produce pure populations of cells that grow into the protective myelin coating on nerves in mice. Their process opens a door to research and potential treatments for multiple sclerosis, cerebral palsy and other demyelinating diseases afflicting millions of people worldwide.

26 Sep 2011

Researchers discover cellular origins of breast cancer

Identifying the cellular origins of breast cancer might lead to earlier diagnosis and more efficient management of the disease. New research led by Charlotte Kuperwasser of Tufts University School of Medicine (TUSM) has determined that common forms of breast cancer originate from breast cells known as luminal epithelial cells while rarer forms of breast cancer, such as metaplastic carcinomas, originate from basal epithelial cell types.

23 Sep 2011

Scientists discover crucial connection in skin formation

Skin is the body's armor, protecting us from disease agents, injury, excessive water loss, and cold and heat. Yet mutations in a single gene, the gene for the protein p63, cause numerous diseases and malformations of the uppermost layer of skin - the epidermis - and other tissues. In the epidermis, these range from skin cancers to dysplasias that cause cracking, bleeding, infection, and discoloration.

21 Sep 2011

Abnormal levels of lysophosphatidic acid can trigger congenital hydrocephalus

Scientists at The Scripps Research Institute have found what may be a major cause of congenital hydrocephalus, one of the most common neurological disorders of childhood that produces mental debilitation and sometimes death in premature and newborn children.

8 Sep 2011

CIRM approves stem cell research planning grants for five UC Davis teams

The California Institute for Regenerative Medicine (CIRM), the state stem cell agency, today approved research planning grants for five UC Davis Health System teams that are working to develop human clinical trials to treat illnesses such as Huntington's disease, vascular disease, osteoporosis, HIV/AIDS and airway disease in children.

29 Aug 2011

NeoStem featured on CBS's Eye on New York City

NeoStem, Inc., an international biopharmaceutical company with a focus on cell-based therapeutic development, today announced that the Company was featured on CBS's Eye on New York City on Wednesday evening, August 24, 2011.

26 Aug 2011

Study finds biological indicators that help explain why obese people develop chronic diseases

UC Davis Health System researchers have discovered biological indicators that help explain why some obese people develop chronic diseases such as diabetes and heart disease, and others do not.

25 Aug 2011

Human embryonic stem cell, iPS-derived progeny are similar and developmentally immature

Stem cell researchers at UCLA have discovered that three types of cells derived from human embryonic stem cells and induced pluripotent stem cells are similar to each other, but are much more developmentally immature than previously thought when compared to those same cell types taken directly from human tissue.

18 Aug 2011

Scientists identify potential new target for childhood eye tumor

A research team led by St. Jude Children's Research Hospital scientists has identified a potential new target for treatment of the childhood eye tumor retinoblastoma.

16 Aug 2011

Endothelial progenitor cells may repair leaky blood-brain barrier

University of South Florida Department of Neurosurgery and Brain Repair faculty members have received a $2.6 million grant from the National Institutes of Health to investigate the potential for cells derived from human bone marrow to benefit post-stroke patients by repairing the blood-brain barrier.

12 Aug 2011

New model for amyotrophic lateral sclerosis

By isolating cells from patients' spinal tissue within a few days after death, researchers funded by the National Institutes of Health have developed a new model of the paralyzing disease amyotrophic lateral sclerosis.

12 Aug 2011

Researchers helps explain how the adult brain cleans out dead brain cells and produces new ones

Adult brains generate thousands of new brain cells called neurons each day; however only a small fraction of them survive. The rest die and are consumed by scavenger cells called phagocytes. Until now, scientists have not fully understood how this process works, which phagocytes are unique in the brain, and how the removal of dead neurons influences the production of new neurons.

10 Aug 2011

Researchers clarify role of two proteins key to T-cell development

In the latest issue of Nature, researchers at the Perelman School of Medicine at the University of Pennsylvania clarify the role of two proteins key to T-cell development.

9 Aug 2011

Innovative delivery systems and methods to treat breast cancer

In their lifetime, women have more than a 12 percent risk of being diagnosed with breast cancer. 1 This week, research on novel approaches to breast cancer treatment is being presented at the Era of Hope (EOH) conference, a scientific meeting hosted by the Department of Defense Breast Cancer Research Program (BCRP).

4 Aug 2011

Reprogrammed kidney cells could make transplants and dialysis things of the past

Approximately 60 million people across the globe have chronic kidney disease (CKD), and many will need dialysis or a transplant. Breakthrough research published in the Journal of the American Society Nephrology indicates that patients' own kidney cells can be gathered and reprogrammed.

28 Jul 2011

Invadopodia could help survival of cancer cells

Delicate, threadlike protrusions used by cancer cells when they invade other tissues in the body could also help them escape control mechanisms supposed to eliminate them, a research group led by led by Bradley Davidson in the University of Arizona's department of molecular and cellular biology reports in Nature Cell Biology.

28 Jul 2011

Thalidomide analog shows promise against sickle cell disease

A thalidomide analog is shaping up as a safe, worthy opponent of sickle cell disease, Georgia Health Sciences University researchers report.

19 Jul 2011

Two existing clinical stage clients expand development activities with Progenitor Cell Therapy

Progenitor Cell Therapy (PCT), an internationally recognized cell therapy services and development company, and a wholly-owned subsidiary of NeoStem, Inc., an international biopharmaceutical company with operations in the U.S. and China, announced today that two existing clinical stage biopharmaceutical corporate clients have chosen to expand their development activities with PCT.

18 Jul 2011

Epigenetics affects whether or not stem cells differentiate

Adult stem cells and progenitor cells may not come with a clean genetic slate after all. That's because a new report in the FASEB Journal shows that adult stem or progenitor cells have their own unique "epigenetic signatures," which change once a cell differentiates. This is important because epigenetic changes do not affect the actual make up in a cell's DNA, but rather, how that DNA functions.

1 Jul 2011

Innovative adult stem cell approach could help eliminate obesity

Innovative adult stem cell research by scientists at The University of Texas Health Science Center at Houston could aid efforts to apply the brakes to stem cells that produce the type of fat ringing the waists of millions. Research appeared today online ahead of the print issue of Cell Stem Cell.

17 Jun 2011