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Data from Flexion Therapeutics' FX006 Phase 2b trial for OA to be presented at ACR/ARHP meeing

Flexion Therapeutics, Inc. announced today that new data from a Phase 2b dose-ranging trial of the company's lead compound, FX006, in osteoarthritis has been accepted for an oral presentation at the 2013 Annual Scientific Meeting of the American College of Rheumatology and the Association of Rheumatology Health Professionals.

2 Oct 2013

Minimally invasive treatments for lumbar spinal stenosis: an interview with James Corbett, President & Chief Executive Officer of Vertos Medical

Lumbar spinal stenosis (LSS) is a degenerative, age-related narrowing of the lower spinal canal that causes pressure on the nerves, leading to pain and reduced mobility. Symptoms include pain, numbness, or tingling in the lower back, legs, or buttocks, which limits your ability to stand or walk.

30 Sep 2013

Psoriasis and the nervous system: an interview with Dr Nicole Ward, Case Western Reserve University

The prevalence of skin disease exceeds that of obesity, hypertension or cancer. One in three individuals in the United States suffers with a skin disease, with ~2-3% of the American population suffering from psoriasis.

27 Sep 2013

House and Senate negotiators reaching agreement on compounding pharmacy legislation

The measure would apply uniform national standards to pharmacy compounding while enacting a track-and-trace system to ensure the safety of drugs throughout the supply chain.

27 Sep 2013

Researchers identify existence of precursor cells in early prostate cancers

A team of cancer researchers at the University of California, San Diego has identified the existence of precursor cells in early prostate cancers. These cells are resistant to androgen-deprivation therapy, and may drive the subsequent emergence of recurrent or metastatic prostate cancer.

26 Sep 2013

Researchers make new breakthroughs in brain circuitry controlling fertility

In a landmark discovery, the final piece in the puzzle of understanding how the brain circuitry vital to normal fertility in humans and other mammals operates has been put together by researchers at New Zealand's University of Otago.

21 Sep 2013

Research: Steroids in spinal shots may not provide relief from lower back pain

New research from Johns Hopkins suggests that it may not be the steroids in spinal shots that provide relief from lower back pain, but the mere introduction of any of a number of fluids, such as anesthetics and saline, to the space around the spinal cord.

18 Sep 2013

VBP15 drug shows early promise for treatment of Duchenne muscular dystrophy

A preclinical study led by researchers at Children's National Medical Center has found that a new oral drug shows early promise for the treatment of Duchenne muscular dystrophy.

18 Sep 2013

New study shows advances in care for women who suffer from recurrent miscarriage

A team of researchers, led by the University of Warwick, have published new data that could prove vital for advances in care for women who suffer from recurrent miscarriage.

12 Sep 2013

Improved lung function in patients with moderate asthma severity observed with investigational Tiotropium

Boehringer Ingelheim will present a pooled analysis of new data from the Phase 3 UniTinA-asthma® program at the European Respiratory Society (ERS) Annual Congress 2013 in Barcelona. The data from the individual MezzoTinA-asthma® Phase 3 studies (NCT01340209 and NCT00565266), from which the pooled data are derived, show the addition of tiotropium delivered via the Respimat® inhaler to medium-dose maintenance inhaled corticosteroid (ICS) therapy (defined as 400-800 µg budesonide/day or equivalent) improved lung function and provided sustained bronchodilation over 24 hours in patients with moderate asthma and airflow limitation. Tiotropium is being investigated to determine the medicine’s efficacy in treating asthma patients and is not currently approved for this indication.

11 Sep 2013

People with severe asthma are less likely to respond to treatment

Barcelona, Spain: People with severe asthma, who are often described as 'steroid-dependent', are actually less likely to respond to the treatment they depend on, when compared to people with mild asthma.

10 Sep 2013

Indicators of poor preoperative health predict risk of major medical complications

For older adults undergoing surgery for spinal stenosis, some simple indicators of poor preoperative health predict a high risk of major medical complications, reports a study in the September 1 issue of Spine. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

4 Sep 2013

Inhaled steroids linked to improved school performance in asthma

Researchers from Greece say that the use of steroid inhalers in elementary school children with asthma may improve school performance over other forms of therapy.

3 Sep 2013

Facebook groups are effective tool for increasing HIV testing among at-risk populations

Peer-led Facebook groups are an acceptable and effective tool for increasing home-based HIV testing among at-risk populations. HIV infection is a major health concern for men who have sex with men (MSM), especially among African Americans and Latinos who have high rates of incident cases and new diagnoses.

3 Sep 2013

Patients attending specialist nurse clinics do not get inferior treatment to that offered by rheumatologists

Patients attending clinical nurse specialist clinics do not get inferior treatment to that offered by consultant rheumatologists, the results of a major new clinical trial have revealed.

29 Aug 2013

In dynamic mind-body interaction, brain recruits cells from immune system to promote anxiety

New research shows that in a dynamic mind-body interaction during the interpretation of prolonged stress, cells from the immune system are recruited to the brain and promote symptoms of anxiety.

22 Aug 2013

Probiotic does not prevent clinical relapse in patients with Crohn's disease

Despite previous data showing beneficial effects, the probiotic Saccharomuces boulardii (S. boulardii) does not prevent clinical relapse in patients with Crohn's disease, according to a new study in Clinical Gastroenterology and Hepatology, the official clinical practice journal of the American Gastroenterological Association.

16 Aug 2013

Tubingen researchers resolve how a plant steroid hormone makes plants grow

If one wants to better understand how plants grow, one must analyse the chemistry of life in its molecular detail. Michael Hothorn from the Friedrich-Miescher-Laboratory of the Max Planck Society in T-bingen and his team are doing just that. Their latest work now reveals that a plant membrane receptor requires a helper protein to sense a growth-promoting steroid hormone and to transduce this signal across the cell membrane.

9 Aug 2013

Symptoms and treatment for facial allergic contact dermatitis

Facial rashes can take on many forms. Whether red, flat, bumpy and dry, or scaly, flaky and itchy, the appearance of a rash on the face can be very distressing.

3 Aug 2013

NIH-funded study finds that rituximab is as effective as standard therapy for severe vasculitis

Administering the drug rituximab once weekly for one month provides the same benefits as 18 months of daily immunosuppressive therapy in people with severe forms of vasculitis, or inflammation of the blood vessels, a study has found.

1 Aug 2013