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Global changes in cancer cells' epigenome may determine disease progression

Genomic studies have illuminated the ways in which malfunctioning genes can drive cancer growth while stunting the therapeutic effects of chemotherapy and other treatments. But new findings from Weill Cornell Medical College investigators indicate that these genes are only partly to blame for why treatment that was at one point effective ultimately fails for about 40 percent of patients diagnosed with the most common form of non-Hodgkin Lymphoma.

21 Apr 2015

New Dream Team dedicated to ovarian cancer research formed at AACR Annual Meeting 2015

Stand Up To Cancer, Ovarian Cancer Research Fund, Ovarian Cancer National Alliance, and National Ovarian Cancer Coalition, along with the American Association for Cancer Research, Scientific Partner to SU2C, announced today the formation of a Dream Team devoted to ovarian cancer research at the AACR Annual Meeting 2015, held here April 18-22.

21 Apr 2015

Mott poll measures public's views about use of medical marijuana for children

Medical marijuana and children don't mix, most Americans say. While nearly two-thirds of people agree that their state should allow medical marijuana for adults, half as many - just over a third - say it should be allowed for children, according to today's University of Michigan C.S. Mott Children's Hospital National Poll on Children's Health that included a national sample of adults in the U.S.

21 Apr 2015

New UM SOM study reveals why thiazide drugs not effective in some patients

Every year, more than 120 million prescriptions are written worldwide for thiazide drugs, a group of salt-lowering medicines used to treat high blood pressure. These drugs are often work very well, and over decades have saved hundreds of thousands of lives.

21 Apr 2015

MGH researchers find probable mechanism associated with risk of developing serious diseases

Massachusetts General Hospital investigators have found the probable mechanism underlying a previously described biomarker associated with the risk of developing serious diseases ranging from cancer to cardiovascular disease and the risk of serious complications. In a paper published in the American Journal of Hematology, the research team reports finding that higher levels of a measure routinely taken as part of the complete blood count - the extent of variation in the size of red blood cells - is caused by reduced clearance of aging cells from the bloodstream.

20 Apr 2015

New drug combination shows promise in patients with metastatic melanoma

Once again, researchers at Penn's Abramson Cancer Center have extended the reach of the immune system in the fight against metastatic melanoma, this time by combining the checkpoint inhibitor tremelimumab with an anti-CD40 monoclonal antibody drug.

20 Apr 2015

New Commission outlines current state of research into sepsis

Leading doctors today [Monday 20 April, 2015] warn that medical and public recognition of sepsis--thought to contribute to between a third and a half of all hospital deaths--must improve if the number of deaths from this common and potentially life-threatening condition are to fall.

20 Apr 2015

Pembrolizumab drug halts tumor growth in 76% of patients with pleural mesothelioma

The PD-1 inhibitor pembrolizumab, a cancer immunotherapy drug, shrank or halted growth of tumors in 76 percent of patients with pleural mesothelioma, a rare and deadly form of cancer that arises in the outer lining of the lungs and internal chest wall, according to a new study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

20 Apr 2015

Pulmonary Hypertension Center at RI Hospital receives PHA accreditation

The Pulmonary Hypertension Center at Rhode Island Hospital is one of the nation's first centers of its kind to be accredited by the Pulmonary Hypertension Association. For those affected by pulmonary hypertension (PH), accreditation assures them and their providers that they have access to the most advanced care available in the country.

20 Apr 2015

Health innovation pioneered in East Midlands to be showcased at international conference 17th April

A ground-breaking training project for junior doctors – developed in Leicester and soon to be launched in Lincolnshire - is being showcased to a global audience of health experts at an international event next Friday (24th April).

17 Apr 2015

Scientists discover protein that boosts immunity to viruses and cancer

Experiments in mice and human cells have shown that the protein promotes the proliferation of cytotoxic T cells, which kill cancer cells and cells infected with viruses...

17 Apr 2015

Donald S. Coffey to receive Margaret Foti Award at AACR Annual Meeting 2015

Donald S. Coffey, PhD, will be honored with the ninth annual American Association for Cancer Research Margaret Foti Award for Leadership and Extraordinary Achievements in Cancer Research at the AACR Annual Meeting 2015, to be held in Philadelphia, April 18-22.

17 Apr 2015

New method for measuring genetic variability may help identify patients with aggressive cancers

A new method for measuring genetic variability within a tumor might one day help doctors identify patients with aggressive cancers that are more likely to resist therapy, according to a study led by researchers now at The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

17 Apr 2015

Robert B. Kiningham receives Founders' Award at 2015 AMSSM Annual Meeting

Robert B. Kiningham, MD, was awarded the Founders' Award at the 24th American Medical Society for Sports Medicine Annual Meeting in Hollywood, Fla. The award is bestowed when AMSSM leadership determines that a member exemplifies the best that a sports medicine physician can be and do.

16 Apr 2015

HeartWare Ventricular Assist System meets primary endpoint in ENDURANCE clinical trial

HeartWare International, Inc., a leading innovator of less invasive, miniaturized circulatory support technologies that are revolutionizing the treatment of advanced heart failure, today announced that data from its first destination therapy clinical trial cohort, ENDURANCE, successfully demonstrated that the trial achieved the primary endpoint.

16 Apr 2015

GW Cancer Institute finalizes competency statements for oncology patient navigators

The George Washington University Cancer Institute has finalized 45 core competency statements for oncology patient navigators, who have become critical members of the health care team. These competency statements were published in the Journal of Oncology Navigation and Survivorship and were created through literature review, focus group data analysis, expert review, and a national survey of oncology patient navigation stakeholders.

16 Apr 2015

Researchers examine how probiotics can help improve health, prevent disease

In recent years, research into the benefits of gut bacteria has exploded. Scientists across the globe are examining how these microbes can help improve health and prevent disease.

16 Apr 2015

NIH-supported clinical trial to test statin use in patients with HIV-related cardiovascular disease

Researchers have begun enrolling participants in a multicenter international clinical trial to test whether statin administration can reduce the risk for major adverse cardiovascular events, such as heart attacks, strokes, and heart disease, in people with HIV infection. The trial is supported by the National Institutes of Health's National Heart, Lung, and Blood Institute and National Institute of Allergy and Infectious Diseases.

16 Apr 2015

New research could transform treatments for patients with Barrett's Oesophagus

New research from the University of Warwick and University Hospitals Coventry and Warwickshire NHS Trust could transform treatments and diagnosis for a common digestive condition which affects thousands of patients.

15 Apr 2015

Board-certified physiatrist Brian Fellechner joins St. Luke’s University Health Network

St. Luke’s University Health Network is pleased to welcome board-certified physiatrist Brian Fellechner, DO, to its medical staff. A graduate of the Philadelphia College of Osteopathic Medicine, Dr. Fellechner completed his residency in physical medicine and rehabilitation at the University of Medicine and Dentistry of New Jersey – New Jersey Medical School in Newark, New Jersey where he served as chief resident at the Kessler Institute for Rehabilitation.

15 Apr 2015

Medical School News and Research

Global changes in cancer cells' epigenome may determine disease progression

New Dream Team dedicated to ovarian cancer research formed at AACR Annual Meeting 2015

Mott poll measures public's views about use of medical marijuana for children

New UM SOM study reveals why thiazide drugs not effective in some patients

MGH researchers find probable mechanism associated with risk of developing serious diseases

New drug combination shows promise in patients with metastatic melanoma

New Commission outlines current state of research into sepsis

Pembrolizumab drug halts tumor growth in 76% of patients with pleural mesothelioma

Pulmonary Hypertension Center at RI Hospital receives PHA accreditation

Health innovation pioneered in East Midlands to be showcased at international conference 17th April

Scientists discover protein that boosts immunity to viruses and cancer

Donald S. Coffey to receive Margaret Foti Award at AACR Annual Meeting 2015

New method for measuring genetic variability may help identify patients with aggressive cancers

Robert B. Kiningham receives Founders' Award at 2015 AMSSM Annual Meeting

HeartWare Ventricular Assist System meets primary endpoint in ENDURANCE clinical trial

GW Cancer Institute finalizes competency statements for oncology patient navigators

Researchers examine how probiotics can help improve health, prevent disease

NIH-supported clinical trial to test statin use in patients with HIV-related cardiovascular disease

New research could transform treatments for patients with Barrett's Oesophagus

Board-certified physiatrist Brian Fellechner joins St. Luke’s University Health Network

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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