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Clover Biopharma's new trimeric subunit vaccine candidate prevents COVID-19 in monkeys

The vaccine candidate produced a high level of neutralizing antibodies in animal models. Rhesus macaques immunized with the vaccine candidate showed reduced viral loads in the lungs. The research is published on the preprint server bioRxiv.

28 Sep 2020

Young adults now driving force behind the ongoing COVID-19 pandemic says CDC

The Centers for Disease Control and Prevention (CDC) has released a report stating that the ongoing COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is on the rise among young adults and this rise is preventing the pandemic from abating.

27 Sep 2020

Yale designates three independent laboratories to perform SalivaDirect COVID-19 test

Yale has designated three independent laboratories to perform the university-developed SalivaDirectTM COVID-19 test.

26 Sep 2020

New research projects intend to alleviate farmer and rancher stress

The stress level in rural communities is off the charts. Farm and ranch closures, land forfeitures, labor issues and more contribute, and according to a 2015 report from the Centers for Disease Control and Prevention - a full five years before the COVID-19 pandemic hit - rates of suicide in rural communities measured twice that of urban areas.

26 Sep 2020

Marine bacteria optimize nutrient uptake by switching between dispersal and resource exploitation

To stay, or not to stay? When it comes to nutrient resource patches, researchers from Japan and Switzerland have discovered that marine bacteria have a knack for exploiting them efficiently, timing movements between patches to get the best resources.

26 Sep 2020

New approach uses AI to identify which early stage breast cancers will spread

About 1 in 5 new breast cancers are caught at their earliest stages, before they've spread from milk ducts into the surrounding breast tissue.

25 Sep 2020

University of Minnesota receives funding to initiate research on diabetes drug as a COVID-19 treatment

University of Minnesota Medical School researchers received funding from the Parsemus Foundation to initiate research on the widely-used diabetes medication, metformin, available globally as an inexpensive generic drug for prevention and treatment for COVID-19.

25 Sep 2020

FDA approves first drug for patients with hypereosinophilic syndrome in nearly 14 years

Today, the U.S. Food and Drug Administration approved Nucala (mepolizumab) for adults and children aged 12 years and older with hypereosinophilic syndrome (HES) for six months or longer without another identifiable non-blood related cause of the disease.

25 Sep 2020

Study identifies potential drug target for dangerous E. coli infections

Escherichia coli, known as E. coli, are bacteria which many people associate with causing mild food poisoning, but some types of E. coli can be fatal.

25 Sep 2020

Emergency departments of hospitals generate significant amounts of harmful waste

Emergency departments of hospitals generate significant amounts of environmentally harmful waste which could be reduced through basic changes to disposal policies and practices, while producing lower operating costs, researchers from Massachusetts General Hospital (MGH) have found.

25 Sep 2020

Study assesses cardiovascular and renal outcomes for ertugliflozin in patients with type 2 diabetes

A new study led by a cardiologist from Brigham and Women's Hospital has assessed the cardiovascular and renal outcomes for ertugliflozin, an SGLT2 inhibitor prescribed for patients with type 2 diabetes to help them control blood sugar levels

25 Sep 2020

FDA issues updated recommendations concerning dental amalgam

Part of our role in protecting patients is to regularly evaluate, monitor and update scientific evidence on the risks from medical devices—including issues related to the materials used in devices, such as metals.

25 Sep 2020

Researchers use natural pigment for screening cell viability

Synthetic dyes are commonly used to assess the toxicity of chemical compounds in cell cultures. However, these dyes damage cells, rendering the cultures useless for long-term experiments.

25 Sep 2020

Experimental cancer drug AR-12 inhibits SARS-CoV-2 virus

Nine months into the global pandemic, which has infected more than 32 million people, there is still no approved effective and safe drug or vaccine against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

24 Sep 2020

Linoleic acid binds SARS-CoV-2 spike protein

Now, a team of researchers at the Max Planck-Bristol Center for Minimal Biology and Bristol's School of Biochemistry has identified a druggable pocket in the virus's spike protein that can be used to prevent the infection of cells. The study findings, published in the journal Science, are a groundbreaking discovery that will help develop new therapies and drugs to stem the growing pandemic.

24 Sep 2020

Researchers solve the mystery of how giant molecular proton pump works

Mitochondria are the powerhouses of our cells, generating energy that supports life. A giant molecular proton pump, called complex I, is crucial: It sets in motion a chain of reactions, creating a proton gradient that powers the generation of ATP, the cell's fuel.

24 Sep 2020

FDA takes actions to help provide safe, more affordable drugs to Americans

Today, the U.S. Department of Health and Human Services and the U.S. Food and Drug Administration took actions to help provide safe, effective, and more affordable drugs to American patients as part of the Safe Importation Action Plan, fulfilling the aspect of the July Executive Order on drug pricing to complete the rulemaking to allow states to import certain prescription drugs from Canada.

24 Sep 2020

Federal restrictions on corneal donations prevent vision-restoring surgery

Some forms of blindness and visual impairment can be cured with a corneal transplant surgery using donated eye tissue. However, federal regulations in the United States and Canada severely restrict the ability of sexually active gay and bisexual men from donating their eye tissue.

24 Sep 2020

These secret safety panels will pick the COVID vaccine winners

Most Americans have never heard of Dr. Richard Whitley, an expert in pediatric infectious diseases at the University of Alabama-Birmingham.

24 Sep 2020

Automated computational protocol identifies potential SARS-CoV-2 MPro inhibitor

As scientists race to discover new and effective antiviral drugs against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), many novel approaches are being utilized. Now, a new study published on the preprint bioRxiv in September 2020 reports on the discovery of a potentially beneficial enzyme blocker that could inhibit SARS-CoV-2 viral replication.

24 Sep 2020