Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Mammals have the power to regenerate

Researchers at the University of Pennsylvania School of Medicine have found that hair follicles in adult mice regenerate by re-awakening genes once active only in developing embryos.

18 May 2007

Researchers identify the cancer stem cell for rhabdomyosarcoma

As published in the June 1 issue of Genes & Development, Dr. Leonard Zon (Children's Hospital Boston) and colleagues have identified the cancer stem cell for rhabdomyosarcoma, the most common soft-tissue sarcoma of childhood.

17 May 2007

Project aims to develop stem cell lines that genetically match human patients

These lines would allow scientists to better study conditions ranging from diabetes to Parkinson's disease, and they would provide the basis for potential patient-specific stem cell treatments.

17 May 2007

Cancer cells can be killed by a new cancer drug that is triggered by a laser light

Their paper describes how these new photosensitizer drugs can only be activated by light once they have been localized in the target tumour cells. For the first time Zheng and Wilson have demonstrated that tumour cells can be selectively attacked using a PDT.

17 May 2007

Hair loss may be reversible

Scientists who have helped create new hair cells on the skin of mice say hair loss may be reversible.

16 May 2007

Cells that cause Ewing's sarcoma identified

Inserm researchers at the Institut Curie have identified the cells that cause Ewing’s sarcoma.

16 May 2007

Adult bone marrow stem cells may help cure certain genetic eye diseases

Scientists have completed a study using mice which showed that bone marrow stem cells can switch roles and produce keratocan, a natural protein involved in the growth of the cornea, the transparent, outer layer of the eyeball.

11 May 2007

It is highly unlikely that older women generate new eggs

Tilly reported the discovery of stem cells capable of migrating from bone marrow to mouse ovaries and generating new eggs there. The research fueled hopes that a new treatment - such as bone marrow transplantation - might one day help older women regain their fertility.

9 May 2007

Researchers create agent that protects cells from the lethal effects of radiation

No drugs exist to protect the public from the high levels of radiation that could be released by a "dirty" bomb or nuclear explosion.

9 May 2007

Adult stem cells play no role in insulin production

Diabetes researchers, investigating how the body supplies itself with insulin, discovered to their surprise that adult stem cells, which they expected to play a crucial role in the process, were nowhere to be found.

8 May 2007

Heart-assist devices may help some end-stage heart failure patients avoid transplant

Implanted pumps improved heart function enough in a small percentage of patients awaiting a heart transplant that they were able to leave the hospital without a pump and without a new heart, according to a study in Circulation: Journal of the American Heart Association.

8 May 2007

Master regulator for epithelial tissue regeneration found

The skin's ability to replace the tissue it sloughs off is controlled by a variety of genes.

4 May 2007

Study of fatigue in cancer patients

Fatigue is one of the most common and distressing symptoms cancer patients experience during chemotherapy and radiation treatment, but it's difficult for health care professionals to accurately assess its severity.

4 May 2007

Scientists work out mechanism underlying asymmetric cell division in nematode worms

When a cell divides, normally the result is two identical daughter cells. In some cases however, cell division leads to two cells with different properties. This is called asymmetric cell division and plays an important role in embryonic development and the self-renewal of stem cells.

4 May 2007

Lab-on-a-chip speeds proteomics research

In recent years, the science of biology has been dominated by genomics, the study of genes and their functions.

4 May 2007

Mesoblast receives FDA clearance for heart attack stem cell trial

Australia's adult stem cell company, Mesoblast Limited has announced that the United States Food and Drug Administration (US FDA) has cleared the Investigational New Drug Submission (IND) of its US-based sister company, Angioblast Systems Inc., to commence a Phase 2 clinical trial of its allogeneic, or 'off-the-shelf', adult stem cells for patients with heart attacks.

4 May 2007

U.S. Supreme Court decision boosts stem cell patent challenge

A U.S. Supreme Court decision in favor of KSR International Corp. on Monday strengthens challenges against overreaching human embryonic stem cell patents held by an affiliate of the University of Wisconsin, the Foundation for Taxpayer and Consumer Rights (FTCR) and the Public Patent Foundation (PUBPAT) said.

2 May 2007

Unstable leukemia stem cells may predispose patients to drug resistance

The BCR-ABL gene in chronic myeloid leukemia stem cells has a tendency to quickly mutate, and this may help explain why patients are predisposed to resistance to drugs like imatinib that target that gene, according to a study in the May 2 Journal of the National Cancer Institute.

2 May 2007

Lawmakers have proposed 'witch's brew' of biotech bills

Lawmakers in recent months "have stirred up a witch's brew of initiatives that is cause for some concern -- not only for the biotech industry, but for all Americans," James Mullen, president and CEO of Biogen and chair of the Biotechnology Industry Organization, writes in a Wall Street Journal opinion piece.

1 May 2007

Smelling for first time results from knowing abnormalities in congenital loss of smell

New discoveries about the biochemical basis of the majority of cases of the congenital inability to smell any odor, no matter how strong, have enabled their discoverer, Dr. Robert I. Henkin, director of The Taste and Smell Clinic in Washington, DC, to treat such patients, enabling them to smell something for the first time in their lives.

1 May 2007