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Scientists identify multi-kinase inhibitors that can effectively block SARS-CoV-2-mediated cytokine release

Researchers investigated the efficacy of two multi-kinase inhibitors, olverembatinib and ponatinib, in inhibiting SARS-CoV-2 omicron-mediated cytokine release in human peripheral blood mononuclear cells.

10 Feb 2022

The effect of Omicron mutations at the fundamental atomic scale level

The present study provided interesting insights into the interactions of AAs at the interface between SARS-CoV-2 spike and human ACE2 receptors.

10 Feb 2022

Omicron resists antibodies, causes less severe disease than previous SARS-CoV-2variants

In two recent studies, researchers at Washington University School of Medicine in St. Louis found evidence that the omicron variant of the virus that causes COVID-19 causes less severe disease than previous variants — at least in rodents — but that many antibody-based therapies may not be effective against it.

10 Feb 2022

Measuring T cell responses to SARS-CoV-2 vaccination and infection in healthcare workers with two different assays

The purpose of this study was to compare the OI TSPOT with the in-house PITCH ELISpot for reporting T cell responses specific to SARS-CoV-2 spike and structural proteins.

10 Feb 2022

Researchers reveal new therapeutic way to block oncogenic RAS mutants

As a 10-year journey comes to fruition, MUSC Hollings Cancer Center researcher John O'Bryan, Ph.D., and colleagues have demonstrated a new therapeutic way to block a protein that is frequently mutated in cancers.

9 Feb 2022

Super-resolution imaging of the human coronavirus genome during infection

Using high-throughput confocal super-resolution microscopy, scientists visualize the genomic material of the human coronavirus HCoV-229E.

9 Feb 2022

Newborn antibodies following maternal COVID-19 vaccination persist for up to six months

A new study compares antibody levels in newborns born from mothers vaccinated against COVID-19 and to maternal infection with SARS-CoV-2.

9 Feb 2022

How SARS-CoV-2 infection progresses throughout the respiratory system

Researchers discuss the progression of SARS-CoV-2 infection throughout the respiratory epithelium.

9 Feb 2022

Induction and stability of vaccine-specific antibodies in multiple sclerosis patients on different disease-modifying therapies

Researchers have investigated the lack of response to treatment in certain multiple sclerosis patients.

9 Feb 2022

Innate immune specificity is driven by the nervous system, study suggests

Research led by Washington State University scientists supports a novel theory that the innate immune system people are born with can respond differently to specific pathogens.

9 Feb 2022

Scientists identify a new protein that prevents cancer cell migration

When tumors spread, cancer cells migrate to other parts of the body through the blood or lymphatic vessels. Scientists at the Institute of Science and Technology Austria have now found a new protein that prevents cancer cells from doing so by making them stick more tightly to their surroundings.

9 Feb 2022

Study explores adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants post-immunization in cancer patients

Researchers have conducted a prospective, longitudinal cohort study to analyze COVID-19 immunity in patients with cancer.

9 Feb 2022

Protein C News and Research

Scientists identify multi-kinase inhibitors that can effectively block SARS-CoV-2-mediated cytokine release

The effect of Omicron mutations at the fundamental atomic scale level

Omicron resists antibodies, causes less severe disease than previous SARS-CoV-2variants

Measuring T cell responses to SARS-CoV-2 vaccination and infection in healthcare workers with two different assays

Researchers reveal new therapeutic way to block oncogenic RAS mutants

Super-resolution imaging of the human coronavirus genome during infection

Newborn antibodies following maternal COVID-19 vaccination persist for up to six months

How SARS-CoV-2 infection progresses throughout the respiratory system

Induction and stability of vaccine-specific antibodies in multiple sclerosis patients on different disease-modifying therapies

Innate immune specificity is driven by the nervous system, study suggests

Scientists identify a new protein that prevents cancer cell migration

Study explores adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants post-immunization in cancer patients

Reducing mucin secretion provides a way to control chemoresistance of colorectal cancers

Study shows how gut bacteria could undermine immunity in pancreatic cancer

The B and T cell responses to SARS-CoV-2

Antibody drug improves survival rates in canine prostate cancer model

New method decodes the role of DDX41 protein in preventing double-strand breaks in DNA

The impact of SARS-CoV-2 variants on clinical trajectory and outcome

Study identifies lower viral load in the nasopharyngeal samples of patients infected with SARS-CoV-2 Omicron variant

Efficacy of MVA-CoV2-S vaccination to prevent SARS-CoV-2 cerebral infection and associated damage

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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