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New cell powerhouse sequencing technique may provide clearer picture of inherited disease risk

A new sequencing technique may provide a clearer picture of how genes in mitochondria, the "powerhouses" that turn sugar into energy in human cells, shape each person's inherited risk for diabetes, heart disease and cancer, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published online this week in the journal Nucleic Acids Research.

5 Mar 2015

Study shows how mutations that cause Alzheimer's disease lead to neurodegeneration, dementia

A study from researchers at Massachusetts General Hospital and Brigham and Women's Hospital reveals for the first time exactly how mutations associated with the most common form of inherited Alzheimer's disease produce the disorder's devastating effects.

5 Mar 2015

New study shows who benefits most from statin therapy

Research has demonstrated that the risk for developing coronary heart disease depends on a host of risk factors that are related both to lifestyle and genetics. In a new study from Brigham and Women's Hospital, Washington University School of Medicine in St. Louis, and Massachusetts General Hospital, researchers tested whether a composite of genetic variants could identify the risk of cardiovascular death and heart attacks as well as identify individuals who derived greater clinical benefit from statin therapy.

4 Mar 2015

Non-drug approaches work better in people with Alzheimer's disease, dementia

Doctors write millions of prescriptions a year for drugs to calm the behavior of people with Alzheimer's disease and other types of dementia. But non-drug approaches actually work better, and carry far fewer risks, experts conclude in a new report.

4 Mar 2015

Key questions about colorectal cancer answered

Colorectal cancer is the fourth most common cancer in the U.S., with more than 136,000 new patients diagnosed last year. But thanks to increased awareness about screenings, the death rate from colorectal cancer has been dropping for more than 20 years.

4 Mar 2015

Common antidepressant medications not helpful for people with mood, anxiety disorders

Studies indicate that the majority of people with mood and anxiety disorders who receive the most commonly prescribed class of antidepressant medications, Selective Serotonin Reuptake Inhibitors or SSRI's, are not helped by these medications. SSRIs are designed to increase serotonin, a neurotransmitter in the brain that is key to maintenance of mood.

4 Mar 2015

OTC medications, dietary and herbal supplements cause drug-induced acute liver failure

Drug-induced acute liver failure is uncommon, and over-the-counter medications and dietary and herbal supplements -- not prescription drugs -- are its most common causes, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

4 Mar 2015

Investigational drug may attack cause of vaso-occlusion crises in sickle cell anemia

Treatment for painful episodes of blood vessel obstruction in sickle cell anemia is currently limited to controlling pain, but an investigational therapy might be able to interfere with the underlying cause of these events, known as vaso-occlusion crises, researchers at Duke Medicine report.

3 Mar 2015

New study shows association between BPA exposure and ASD in children

A newly published study is the first to report an association between bisphenol-A (BPA), a common plasticizer used in a variety of consumer food and beverage containers, with autism spectrum disorder (ASD) in children.

3 Mar 2015

Scientists find gorilla origins in two human AIDS virus lineages

Two of the four known groups of human AIDS viruses (HIV-1 groups O and P) have originated in western lowland gorillas, according to an international team of scientists from the Perelman School of Medicine at the University of Pennsylvania, the University of Montpellier, the University of Edinburgh, and others.

3 Mar 2015

Successful cognitive behavioral therapy for childhood anxiety provides long-term benefits

Penn Medicine researchers found that patients who did not respond to cognitive behavioral therapy (CBT) for anxiety in childhood had more chronic and enduring patterns of suicidal ideation at 7 to 19 years after treatment.

3 Mar 2015

MIT researchers develop new nanodevice that can help overcome drug resistance

Chemotherapy often shrinks tumors at first, but as cancer cells become resistant to drug treatment, tumors can grow back. A new nanodevice developed by MIT researchers can help overcome that by first blocking the gene that confers drug resistance, then launching a new chemotherapy attack against the disarmed tumors.

3 Mar 2015

UTHealth study focuses on new cognitive behavioral therapy to treat PTSD, substance use disorders

A new cognitive behavioral therapy designed to treat both post-traumatic stress disorder (PTSD) and substance use disorders is the focus of research at The University of Texas Health Science Center at Houston Medical School.

3 Mar 2015

Scientists sequence genome of hookworm

In an advance that may potentially lead to new treatments for parasitic hookworms, scientists at the University of Massachusetts Medical School and Cornell University have sequenced the genome of the hookworm, Ancylostoma ceylanicum.

3 Mar 2015

People with diabetes more prone to depression, anxiety

People with diabetes are more prone to anxiety and depression than those with other chronic diseases that require similar levels of management. The reasons for this aren't well understood, but Joslin Diabetes Center researchers have discovered one potential explanation.

2 Mar 2015

U-M researchers reveal key role of two enzymes that help the body to remove cholesterol, other lipids

With the aid of X-ray crystallography, researchers at the University of Michigan have revealed the structures of two closely related enzymes that play essential roles in the body's ability to metabolize excess lipids, including cholesterol.

2 Mar 2015

Pediatricians, health care providers encounter requests to postpone vaccinations

Pediatricians are facing increasing pressure from some parents who want to spread out the recommended vaccine schedule for their children by postponing vaccines, pointing to a need for improved programs that support timely vaccinations, according to a new study by researchers at the University of Colorado School of Medicine at the Anschutz Medical Campus.

2 Mar 2015

Study reports 10% reduction in overall C-section births in Portugal

A new study reports a significant decline in the rate of cesarean section (C-section) births in Portugal. Findings published in Acta Obstetricia et Gynecologica Scandinavica, a journal of the Nordic Federation of Societies of Obstetrics and Gynecology, indicate a 10% reduction in overall C-section rates between 2009 and 2014, with a 14% reduction in state-hospitals during the same time period.

2 Mar 2015

Study shows only 44% of black males prefer to be investigated for prostate cancer

The incidence of prostate cancer among men of Afro-Caribbean origin is higher than in white men, they are more likely to be diagnosed as emergencies and their mortality rates are higher.

2 Mar 2015

Final agenda for upcoming HxRefactored Conference announced

Health 2.0 and Mad*Pow announce the final agenda for the upcoming HxRefactored Conference, April 1-2 in Boston, Massachusetts. HxRefactored is a revolutionary design and technology conference gathering over 600 designers, developers, and entrepreneurs in health care for two days of thought provoking panels, workshops and discussions on how to improve the quality of the health experience.

28 Feb 2015

Medical School News and Research

New cell powerhouse sequencing technique may provide clearer picture of inherited disease risk

Study shows how mutations that cause Alzheimer's disease lead to neurodegeneration, dementia

New study shows who benefits most from statin therapy

Non-drug approaches work better in people with Alzheimer's disease, dementia

Key questions about colorectal cancer answered

Common antidepressant medications not helpful for people with mood, anxiety disorders

OTC medications, dietary and herbal supplements cause drug-induced acute liver failure

Investigational drug may attack cause of vaso-occlusion crises in sickle cell anemia

New study shows association between BPA exposure and ASD in children

Scientists find gorilla origins in two human AIDS virus lineages

Successful cognitive behavioral therapy for childhood anxiety provides long-term benefits

MIT researchers develop new nanodevice that can help overcome drug resistance

UTHealth study focuses on new cognitive behavioral therapy to treat PTSD, substance use disorders

Scientists sequence genome of hookworm

People with diabetes more prone to depression, anxiety

U-M researchers reveal key role of two enzymes that help the body to remove cholesterol, other lipids

Pediatricians, health care providers encounter requests to postpone vaccinations

Study reports 10% reduction in overall C-section births in Portugal

Study shows only 44% of black males prefer to be investigated for prostate cancer

Final agenda for upcoming HxRefactored Conference announced

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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