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TSRI scientists to study structural rules that govern nuclear receptors

A consortium of scientists from both campuses of The Scripps Research Institute (TSRI) has been awarded $2.7 million from the National Institute of General Medical Sciences of the National Institutes of Health to study the structural rules that govern a large superfamily of proteins that help regulate critical functions such as reproduction, development and metabolism.

24 Oct 2012

Warning against colloids in fluid resuscitation

Hydroxyethyl starch offers no benefits over saline for fluid resuscitation in critically ill patients and may have renal consequences, shows a randomized trial.

23 Oct 2012

'Fresher' blood transfusion does not mean better outcomes

Blood that has been stored for 2 weeks or more before being used in transfusions for critically ill patients does not appear to cause adverse effects, report US researchers.

22 Oct 2012

$Researchers find new way to assess risk of osteoporosis, bone fractures in women$

Researchers find new way to assess risk of osteoporosis, bone fractures in women

For women of mixed racial or ethnic backgrounds, a new method for measuring bone health may improve the odds of correctly diagnosing their risk of osteoporosis and bone fractures, according to a UCLA-led study.

20 Oct 2012

Daily whole body vibration may combat prediabetes in adolescents

Daily sessions of whole-body vibration may combat prediabetes in adolescents, dramatically reducing inflammation, average blood glucose levels and symptoms such as frequent urination, researchers report.

20 Oct 2012

Intermediate-acting neuromuscular block use ‘needs revisiting’

The use of intermediate-acting neuromuscular blocking agents during general anesthesia may increase the risk for clinically meaningful respiratory complications, researchers report in the BMJ.

17 Oct 2012

Northwestern scientists to request EPA to update guidelines for reproductive health research

A team of Northwestern University scientists will meet with Environmental Protection Agency (EPA) administrators in Washington D.C. Oct. 18 to advocate for important changes in the agency's guidelines for reproductive health research.

17 Oct 2012

$IOF report: 80% of patients with fracture are not screened for osteoporosis or risk of future falls$

IOF report: 80% of patients with fracture are not screened for osteoporosis or risk of future falls

Today, the International Osteoporosis Foundation (IOF) released a new report, revealing approximately 80 percent of patients treated in clinics or hospitals following a fracture are not screened for osteoporosis or risk of future falls. Left untreated, these patients are at high risk of suffering secondary fractures and facing a future of pain, disfigurement, long-term disability and even early death.

12 Oct 2012

Tourniquet timing alters foot surgery pain outcomes

The timing of thigh tourniquet application may affect pain control in patients undergoing forefoot surgery, research published in Foot and Ankle Surgery suggests.

11 Oct 2012

Simple test confirms correct catheter placement

Injecting sodium bicarbonate into a peripheral intravenous catheter is a straightforward means of testing its placement and patency in mechanically ventilated children, say researchers.

10 Oct 2012

Alarms could be key to avoiding intraoperative awareness

Bispectral index monitoring is unlikely to be better than monitoring based on anesthetic concentrations for preventing intraoperative awareness, shows a randomized trial.

3 Oct 2012

Postsurgery mortality rates vary across Europe

Europe-wide data suggest that mortality rates after noncardiac surgery are higher than expected, and vary substantially by country, reports an international research team in The Lancet.

27 Sep 2012

Developing world lagging in anesthesia safety

Mortality after general anesthesia has declined over the past 50 years, but the greatest gains have been in developed countries, shows a systematic review in The Lancet.

26 Sep 2012

Low blood sugar danger for critically ill

Further analysis of the NICE-SUGAR trial shows a dose‑response relationship between the degree of hypoglycemia and the risk for death in critically ill patients.

25 Sep 2012

Low levels of vitamin D associated with higher risk of heart attack and early death

New research from the University of Copenhagen and Copenhagen University Hospital shows that low levels of vitamin D are associated with a markedly higher risk of heart attack and early death. The study involved more than 10,000 Danes and has been published in the well-reputed American journal Arteriosclerosis, Thrombosis and Vascular Biology.

24 Sep 2012

Amgen receives FDA approval for Prolia to treat bone loss in men with osteoporosis

Amgen today announced the U.S. Food and Drug Administration (FDA) approved a new indication for Prolia (denosumab) as a treatment to increase bone mass in men with osteoporosis at high risk for fracture.

21 Sep 2012

i-gel airway device provides reliable anesthesia ventilation

The i-gel supraglottic airway device provides reliable ventilation in patients under anesthesia, results of a prospective multicentre observational study show.

19 Sep 2012

Alarm raised over preoperative hyponatremia

Preoperative hyponatremia is common and, even when mild, carries a risk for perioperative complications and mortality, shows a large cohort study.

12 Sep 2012

Study sheds light on how high-fibre diet affects the gut environment

Savvy consumers and health professionals know that fibre is an essential nutrient associated with important health benefits, yet barriers such as overall poor tolerance to higher-fibre diets may be why average intake is far less than experts recommend.

7 Sep 2012

On-the-spot test aids postsurgical coagulopathy management

Point-of-care thromboelastometric and aggregometric testing helps to reduce exposure to allogenic blood products in patients with coagulopathy after cardiac surgery, a randomized trial shows.

5 Sep 2012