Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

New bioprinting process uses ultrashort peptides to print hydrogel scaffolds

A new automated process prints a peptide-based hydrogel scaffold containing uniformly distributed cells. The scaffolds hold their shapes well and successfully facilitate cell growth that lasts for weeks.

5 Apr 2021

Changing diet and exercise can make chemotherapy more effective in youth with leukemia

Overweight children and adolescents receiving chemotherapy for treatment of leukemia are less successful battling the disease compared to their lean peers.

1 Apr 2021

Modest dietary changes and exercise can improve survival outcomes for young people with leukemia

In some cancers, including leukemia in children and adolescents, obesity can negatively affect survival outcomes. Obese young people with leukemia are 50% more likely to relapse after treatment than their lean counterparts.

1 Apr 2021

Researchers reveal pathways that lead to the development of tissue-resident lymphocytes

Researchers from the University of Science and Technology of China) of the Chinese Academy of Science (CAS), teamed up with scientists from Aix Marseille University, discovered that hematopoietic progenitors possessed the differentiation potential to type 1 innate lymphoid cells in adult liver, and dissected the regulation mechanisms of such cell differentiation, revealing the pathways that lead to the development of tissue-resident lymphocytes.

31 Mar 2021

SwRI researchers part of two collaborative teams receive SAMF bioscience grants

Collaborative teams that include Southwest Research Institute staff received two of six recently awarded San Antonio Medical Foundation (SAMF) bioscience grants. SwRI, in collaboration with UT Health San Antonio and University Health System, received a nearly $200,000 grant to develop machine learning algorithms for cancer detection.

31 Mar 2021

New tissue implant could benefit athletes sidelined with common shoulder injury

For sports fans, nothing beats seeing their favorite athletes compete at the top of their game. But a shoulder injury such as a badly torn rotator cuff threatens to pause or end the career of any athlete in sports ranging from football, basketball and baseball to golf and tennis.

31 Mar 2021

Scientists launch clinical trial of CRISPR gene correction therapy in patients with sickle cell disease

Scientists at UC San Francisco, UC Berkeley and UCLA have received U.S. Food and Drug Administration approval to jointly launch an early phase, first-in-human clinical trial of a CRISPR gene correction therapy in patients with sickle cell disease using the patient's own blood-forming stem cells.

30 Mar 2021

Scientists use specially designed gold nanoparticles to 'seek out' bone stem cells

Researchers at the University of Southampton have developed a new way of using nanomaterials to identify and enrich skeletal stem cells - a discovery which could eventually lead to new treatments for major bone fractures and the repair of lost or damaged bone.

29 Mar 2021

First cell-based gene therapy approved by the FDA for treating multiple myeloma

The U.S. Food and Drug Administration approved Abecma (idecabtagene vicleucel), a cell-based gene therapy to treat adult patients with multiple myeloma who have not responded to, or whose disease has returned after, at least four prior lines (different types) of therapy.

29 Mar 2021

Stem cell depletion could be an important factor behind miscarriage

Depletion of a certain type of stem cell in the womb lining during pregnancy could be a significant factor behind miscarriage, according to a study released today in STEM CELLS.

27 Mar 2021

New blood test makes it easier to follow the progression of multiple myeloma

A new method makes it much easier to follow the progression of multiple myeloma, a form of blood cancer.

26 Mar 2021

DNMT3a plays a key role in regulating HSC responses to infections

Humans are born with tens of thousands of hematopoietic stem cells (HSCs) that collectively ensure lifelong production of blood and immune cells that protect us from infections.

26 Mar 2021

Sargramostim drug can also improve memory in people with mild-to-moderate Alzheimer's disease

A new study suggests that Sargramostim, a medication often used to boost white blood cells after cancer treatments, is also effective in treating and improving memory in people with mild-to-moderate Alzheimer's disease.

24 Mar 2021

Computational analysis helps identify hematological malignancies that elude the human eye

Myelodysplastic syndrome (MDS) is a disease of the stem cells in the bone marrow, which disturbs the maturing and differentiation of blood cells. Annually, some 200 Finns are diagnosed with MDS, which can develop into acute leukemia. Globally, the incidence of MDS is 4 cases per 100,000 person years.

22 Mar 2021

Study finds two drugs capable of slowing bone marrow cancer progression

Primary myelofibrosis (PMF), a relatively rare but painful type of bone marrow cancer, disrupts the body's normal production of blood cells by causing extensive scarring in the bone marrow.

22 Mar 2021

SARS-CoV-2 spike stimulates hyperinflammation via Toll-like receptor 2

A new study, released on the bioRxiv* preprint server, describes the mechanism of inflammation in severe COVID-19, besides revealing a potential new therapeutic target to modulate the severity of COVID-19.

19 Mar 2021

Novel cancer-fighting gene therapy enters phase I clinical trial

Researchers from the MDC and Charité have developed a new gene therapy based around a special T-cell receptor that helps the immune system effectively recognize and fight cancer cells.

18 Mar 2021

Long noncoding RNA plays a vital role in mobilizing immune response after organ transplantation

A long noncoding RNA whose function was previously unknown turns out to play a vital role in mobilizing the immune response following a bone marrow transplant or solid organ transplantation.

17 Mar 2021

Researchers explore difference in reactions to SARS-CoV-2 infection between children and adults

The COVID-19 pandemic has claimed over 2.67 million lives in less than a year and a half. However, it is uncommon in children, with less than 2% of the cases being in individuals below the age of 19. Most of these are of mild severity, with the clinical features of severe COVID-19 being rare in this age group.

17 Mar 2021

People with high BMI may now receive their COVID-19 vaccine in California

Now, California state allows individuals with one of ten comorbidities to get their COVID-19 jabs. This comes after obesity being tagged as COVID-19 vaccine eligibility.

16 Mar 2021

Bone Marrow News and Research

Further Reading

New bioprinting process uses ultrashort peptides to print hydrogel scaffolds

Changing diet and exercise can make chemotherapy more effective in youth with leukemia

Modest dietary changes and exercise can improve survival outcomes for young people with leukemia

Researchers reveal pathways that lead to the development of tissue-resident lymphocytes

SwRI researchers part of two collaborative teams receive SAMF bioscience grants

New tissue implant could benefit athletes sidelined with common shoulder injury

Scientists launch clinical trial of CRISPR gene correction therapy in patients with sickle cell disease

Scientists use specially designed gold nanoparticles to 'seek out' bone stem cells

First cell-based gene therapy approved by the FDA for treating multiple myeloma

Stem cell depletion could be an important factor behind miscarriage

New blood test makes it easier to follow the progression of multiple myeloma

DNMT3a plays a key role in regulating HSC responses to infections

Sargramostim drug can also improve memory in people with mild-to-moderate Alzheimer's disease

Computational analysis helps identify hematological malignancies that elude the human eye

Study finds two drugs capable of slowing bone marrow cancer progression

SARS-CoV-2 spike stimulates hyperinflammation via Toll-like receptor 2

Novel cancer-fighting gene therapy enters phase I clinical trial

Long noncoding RNA plays a vital role in mobilizing immune response after organ transplantation

Researchers explore difference in reactions to SARS-CoV-2 infection between children and adults

People with high BMI may now receive their COVID-19 vaccine in California

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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