DNA Damage News and Research

RSS

Experimental treatment tempers HLH, MS symptoms in mouse models, study shows

Immune diseases like multiple sclerosis and hemophagocytic lymphohistiocytosis unleash destructive waves of inflammation on the body, causing death or a lifetime of illness and physical impairment.

23 May 2017

Study finds link between traffic-related air pollution and telomere shortening in children

Children and teens exposed to high levels of traffic-related air pollution have evidence of a specific type of DNA damage called telomere shortening, reports a study in the May Journal of Occupational and Environmental Medicine.

19 May 2017

Researchers identify DNA repair deficiency in many types of solid tumors

A new investigation of more than 48,000 stored tumor samples finds evidence of a key deficiency in a repair mechanism designed to keep DNA from being mutated and causing cancer.

18 May 2017

Mother cells pass on DNA damage to offspring, study shows

A new University of Colorado Boulder study has shown that some dividing human cells are "kicking the can down the road," passing on low-level DNA damage to offspring, causing daughter cells to pause in a quiescent, or dormant, state previously thought to be random in origin.

17 May 2017

Studies show harmful links between use of e-cigarettes and bladder cancer risk

Data being presented at the 112th Annual Scientific Meeting of the American Urological Association shows harmful links between the use of e-cigarettes and bladder cancer risk, and associates the intensity of smoking traditional cigarettes to a higher risk of mortality among bladder cancer patients

17 May 2017

Mayo Clinic research advances understanding of DNA repair mechanisms

We humans like to think our DNA is well-protected in the nucleus of each cell. But it's a hard life for the hard-working genetic code.

12 May 2017

Scientists identify unusual mutations in endometriosis using gene sequencing tools

Using gene sequencing tools, scientists from Johns Hopkins Medicine and the University of British Columbia have found a set of genetic mutations in samples from 24 women with benign endometriosis, a painful disorder marked by the growth of uterine tissue outside of the womb.

11 May 2017

New technology could hold key to predicting outcome of blood cancer patients

Technology that can detect the length of small DNA structures in cancer cells could hold the key to predicting the outcome of patients with two different types of blood cancer.

11 May 2017

Study reveals role of good-guy protein in initiating and maintaining cancer

Under normal conditions, the CHD4 protein is one of the good guys: it stops cells from transcribing faulty DNA, thereby eliminating potential mutation. But in colon cancer and perhaps other kinds of cancer as well, it appears that this protein becomes a kind of double agent, working for the enemy.

9 May 2017

Researchers develop hybrid nanomaterial for destruction of cancer cells

Most tumors contain regions of low oxygen concentration where cancer therapies based on the action of reactive oxygen species are ineffective.

4 May 2017

Scientists map genetic changes that help drive aggressive brain tumor

University of North Carolina Lineberger Comprehensive Cancer Center researchers and collaborators have mapped genetic changes that help drive an aggressive tumor as it develops in the brain – helping to lay the foundation for targeted treatment of the disease.

3 May 2017

Maternal grandmother’s smoking in pregnancy increases risk of ASD in grandchildren

Scientists from the University of Bristol have looked at all 14,500 participants in Children of the 90s and found that if a girl's maternal grandmother smoked during pregnancy, the girl is 67% more likely to display certain traits linked to autism, such as poor social communication skills and repetitive behaviors.

27 Apr 2017

Study provides new insights on molecular mechanisms that impair muscle stem cells during aging

Researchers at Sanford Burnham Prebys Medical Discovery Institute have identified a previously unrecognized step in stem cell-mediated muscle regeneration.

26 Apr 2017

Researchers discover cancer-fighting properties in beta blockers

A new study finds that carvedilol, a drug typically used to treat high blood pressure, can protect against the sun-induced cell damage that leads to skin cancer. Researchers serendipitously discovered the beta blocker's cancer-fighting properties after making an error in the lab.

24 Apr 2017

Study explains how genetic mutations linked to telomere capping complex contribute to cancers

Scientists at The Wistar Institute have unveiled part of the protein complex that protects telomeres - the ends of our chromosomes. The study, published online in Nature Communications, explains how a group of genetic mutations associated with this protein complex contributes to various cancers.

10 Apr 2017