Depressive Disorder News and Research

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Genetic test announced for suicidal ideation in patients using antidepressant drugs

NeuroMark, a Boulder, Colorado company, announced today the immediate availability of a genetic test to identify people at risk of suicidal ideation - thoughts of committing suicide - when prescribed an antidepressant drug.

27 Sep 2007

Women more depressed and men more impulsive with reduced serotonin functioning

Women and men appear to respond differently to the same biochemical manipulation.

18 Sep 2007

Oncologists critical in managing psychiatric disorders in patients with advanced cancer

Mental illness and emotional distress in patients with advanced cancer are often overlooked by oncologists but, if screened for, can be adequately managed to improve a patient's quality of life.

11 Sep 2007

Seroquel XR tablets approved in Netherlands for the treatment of schizophrenia

AstraZeneca today announced the Netherlands regulatory authority MEB (Medicines Evaluation Board) has approved Seroquel XR (quetiapine fumarate) Extended-Release Tablets, a once-daily medicine for the treatment of schizophrenia in adult patients.

29 Aug 2007

Brain imaging reveals breakdown of normal emotional processing

Brain imaging has revealed a breakdown in normal patterns of emotional processing that impairs the ability of people with clinical depression to suppress negative emotional states.

17 Aug 2007

Faster-acting antidepressant medications

A new study has revealed more about how the medication ketamine, when used experimentally for depression, relieves symptoms of the disorder in hours instead of the weeks or months it takes for current antidepressants to work.

25 Jul 2007

Study to evaluate lithium for the treatment of bipolar disorder

Researchers at the University of Illinois at Chicago are participating in a national study to evaluate lithium for the treatment of bipolar disorder in children and adolescents.

18 Jul 2007

Barr announces tentative approval for generic version of Effexor tablets

Barr Pharmaceuticals, Inc. has announced that its subsidiary PLIVA has received tentative approval from the U.S. Food and Drug Administration (FDA) for its generic version of Wyeth Pharmaceuticals Inc.'s Effexor (Venlafaxine Hydrochloride) Tablets, 25mg, 37.5mg, 50mg, 75mg and 100mg.

27 Jun 2007

Genetic variations may help explain why some men with depression develop suicidal thoughts

Although most patients with depression respond favorably to antidepressant medications, a very small subgroup may experience worse symptoms after beginning treatment, according to background information in the article.

5 Jun 2007

Urgent need for countries to provide a network of community mental health services

For the first time, WHO invited people living with mental disorders to attend the Forum, sending a message to countries that it is important to give a voice to this excluded group to claim their rights and secure their participation in society.

3 Jun 2007

Adding medication improves recovery for elderly with depression

Adding a medication to a standard treatment regimen for major depressive disorder in the elderly improves chances of recovery in those who do not adequately respond to the first-course therapy or who relapse from it, finds a University of Pittsburgh School of Medicine study published in the June issue of the American Journal of Psychiatry, the official journal of the American Psychiatric Association.

3 Jun 2007

New mothers often not asked about depression

The majority of doctors in North Carolina do not probe for signs of postpartum depression in new mothers, according to a survey conducted by researchers at the University of North Carolina at Chapel Hill.

1 Jun 2007

Efficacy and safety of Aripiprazole as adjunctive therapy in major depressive disorder

In adults with major depressive disorder, adding aripiprazole to antidepressant therapy (ADT) resulted in significant improvement in the primary endpoint, the Montgomery-Asberg Depression Rating Scale (MADRS) Total Score.

24 May 2007

FDA wants new warnings on antidepressant medications

The U.S. Food and Drug Administration (FDA) has proposed that makers of all antidepressant medications update the existing black box warning on their products' labeling to include warnings about increased risks of suicidal thinking and behavior, known as suicidality, in young adults ages 18 to 24 during initial treatment (generally the first one to two months).

4 May 2007

FDA - all antidepressants need new warning labels

The Food and Drug Administration (FDA) in the United States wants the manufacturers of antidepressant medications to change the labels on their products.

3 May 2007

Childhood-onset bipolar disorder is more common than believed

In bipolar disorder, also called manic-depressive disorder, a person experiences mood changes that fluctuate between periods of abnormally high energy and extreme depression.

2 May 2007

Pregnant U.S. women commonly smoke

While pregnancy may be considered an effective motivator for smoking cessation, results of a new study by researchers at the Mailman School of Public Health indicate that pregnant U.S. women commonly smoke, placing themselves and their unborn children at risk for health and developmental complications.

25 Apr 2007

Benefits of antidepressants for children far outweigh the risks

Researchers in the United States maintain that a review of research shows that the benefits of antidepressants for children and teens during the first few months of treatment far outweigh the risk of suicide.

22 Apr 2007

Review of all major studies involving anti-depressants in children

Today, the Journal of the American Medical Association (JAMA) published a review of all major studies involving anti-depressants in children and adolescents by a team of researchers from Western Psychiatric Institute in Pittsburgh.

18 Apr 2007

Risks and benefits of antidepressant treatment for children with depression

According to a new study, conducted by the Center for Innovation in Pediatric Practice (CIPP) at Columbus Children's Hospital and published in the April 18 issue of The Journal of the American Medical Association (JAMA), there is more information for parents about the risks and benefits of antidepressant treatment for children with depression and anxiety disorders.

18 Apr 2007