Malignant News and Research

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Emerging protein-based immunotherapies could lead to highly effective cancer treatments

In a new commentary for the journal Science, an associate vice president for research at The University of Texas at Arlington argues that emerging protein-based immunotherapies could lead to highly effective "off-the-shelf" cancer treatments for more patients.

1 Mar 2021

Researchers develop mutant gene-targeted immunotherapy approach to fight cancers

A novel targeted immunotherapy approach developed by researchers at the Ludwig Center, the Lustgarten Laboratory, and Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center employs new antibodies against genetically altered proteins to target cancers.

1 Mar 2021

New method boosts research efforts to eradicate cancer at its source

A new method, described in a study published today in the journal Nature Communications, has the potential to boost international research efforts to find drugs that eradicate cancer at its source.

1 Mar 2021

Scientists receive grant to investigate tumor development within a natural environment

Unlike many of us during the COVID-19 pandemic, biological cells are not isolated from the outside world. Chemical variations, intercellular activity, and other microenvironmental factors impact cell survival.

25 Feb 2021

New glioma-targeted nano-therapeutic offers a potential treatment for glioblastomas

With a survival rate of only five years, the most common and aggressive form of primary brain tumor, glioblastoma multiforme, is notoriously hard to treat using current regimens that rely on surgery, radiation, chemotherapy, and their combinations.

24 Feb 2021

Study findings help explain the diversity of cancers in different Li-Fraumeni patients

The most frequently mutated gene in human cancers is called p53. Patients with Li-Fraumeni syndrome, which is a rare disorder that increases the risk of developing several types of cancer, often have an increased risk to develop cancers at early ages if they inherit p53 mutations.

23 Feb 2021

Scientists discover mechanism by which epithelial tumors cause maturation defects

Conducted on the fly Drosophila, the study shows that tumors caused by chromosomal instability delay entry into the adult phase.

23 Feb 2021

Study shows how m6A regulators influence metabolic heterogeneity of hepatocellular carcinoma

Cancer cells acquire growth advantages over normal cells in myriad ways. Changes in cell programming allow these cells to grow in an uncontrolled fashion, thereby forming the cancer mass.

23 Feb 2021

3D microscopy analysis provides accurate recreation of human glioblastoma’s features

Researchers at the Institut de Neurociències obtained a highly accurate recreation of human glioblastoma’s features using a novel 3D microscopy analysis

19 Feb 2021

Combination therapy produces clinical benefit for early stage non-small cell lung cancer

The first randomized Phase II clinical trial to report on single and combined neoadjuvant immune checkpoint inhibitor therapy in stage I-III non-small cell lung cancer (NSCLC) found combination therapy produced a significant clinical benefit, as assessed by major pathologic response (MPR) rate, as well as enhanced tumor immune cell infiltration and immunological memory.

18 Feb 2021

Study reveals extremely low detection of SARS-CoV-2 on surfaces in oncology facilities

Researchers from Rutgers Cancer Institute of New Jersey, the state's only National Cancer Institute-designated Comprehensive Cancer Center, evaluated the frequency of SARS-CoV-2, the virus that causes COVID-19, on various environmental surfaces in outpatient and inpatient hematology/oncology settings located within Rutgers Cancer Institute and Robert Wood Johnson University Hospital, an RWJBarnabas Health facility.

18 Feb 2021

Researchers evaluate frequency of SARS-CoV-2 in hematology/oncology settings

18 Feb 2021

Accumulation of fatty tissue in the neck predicts adiposity, heart problems

Researchers from the University of Granada warn that an accumulation of fatty tissue in the neck (both the double chin and the deeper deposits, located between muscles and around the cervical vertebrae) is a predictor of central and overall adiposity, cardiometabolic risk, and a pro-inflammatory profile in sedentary young adults.

17 Feb 2021

Study aims to identify proteomic determinants of treatment response in malignant pleural mesothelioma

The National Cancer Institute has granted a $2.5 million, five-year R37 MERIT Award to Dr. Bryan Burt, associate professor of surgery and chief of the Division of General Thoracic Surgery, for his research project titled, "Proteomic Determinants of Response to Checkpoint Blockade in Malignant Pleural Mesothelioma."

16 Feb 2021

Scientists discover new immunotherapy target for malignant brain tumors

Scientists say they have discovered a potential new target for immunotherapy of malignant brain tumors, which so far have resisted the ground-breaking cancer treatment based on harnessing the body's immune system.

15 Feb 2021

FDA approves drug to reduce frequency of chemotherapy-induced bone marrow suppression

Today, the U.S. Food and Drug Administration approved Cosela (trilaciclib) as the first therapy in its class to reduce the frequency of chemotherapy-induced bone marrow suppression in adults receiving certain types of chemotherapy for extensive-stage (when the cancer has spread beyond the lungs) small cell lung cancer.

13 Feb 2021

Malignant News and Research

Emerging protein-based immunotherapies could lead to highly effective cancer treatments

Researchers develop mutant gene-targeted immunotherapy approach to fight cancers

New method boosts research efforts to eradicate cancer at its source

Scientists receive grant to investigate tumor development within a natural environment

New glioma-targeted nano-therapeutic offers a potential treatment for glioblastomas

Study findings help explain the diversity of cancers in different Li-Fraumeni patients

Scientists discover mechanism by which epithelial tumors cause maturation defects

Study shows how m6A regulators influence metabolic heterogeneity of hepatocellular carcinoma

3D microscopy analysis provides accurate recreation of human glioblastoma’s features

Combination therapy produces clinical benefit for early stage non-small cell lung cancer

Study reveals extremely low detection of SARS-CoV-2 on surfaces in oncology facilities

Researchers evaluate frequency of SARS-CoV-2 in hematology/oncology settings

Accumulation of fatty tissue in the neck predicts adiposity, heart problems

Study aims to identify proteomic determinants of treatment response in malignant pleural mesothelioma

Scientists discover new immunotherapy target for malignant brain tumors

FDA approves drug to reduce frequency of chemotherapy-induced bone marrow suppression

Disrupting cancer cell cycle with two commercially available inhibitors causes tumor cell death

New review summarises effect of aquatic pollution on cancer prevalence in wild animals

Inherited genetic variation may affect the response to cancer immunotherapy

Gene panel test enables highly accurate diagnosis of liposarcomas

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