Psychosis News and Research

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Psychosis means abnormal condition of the mind, and is a generic psychiatric term for a mental state often described as involving a "loss of contact with reality". People suffering from psychosis are said to be ''psychotic.''

Schizophrenics appear to rely considerably less on top-down processing during perception

Patients with schizophrenia are able to correctly see through an illusion known as the 'hollow mask' illusion, probably because their brain disconnects 'what the eyes see' from what 'the brain thinks it is seeing', according to a joint UK and German study published in the journal NeuroImage.

6 Apr 2009

FDA approves Symbyax for treatment-resistant depression

The U.S. Food and Drug Administration (FDA) has approved a new indication for Symbyax (olanzapine and fluoxetine HCl capsules), Eli Lilly and Company has announced.

23 Mar 2009

Shire withdraws European application for Daytrana (Methylphenidate Transdermal System)

Shire plc has announced that it has decided to withdraw the European Marketing Authorization Application (MAA) for Daytrana (methylphenidate transdermal system) for the treatment of Attention Deficit Hyperactivity Disorder (ADHD).

16 Mar 2009

Postnatal psychosis more common in older first-time mothers

Women who give birth for the first time after the age of 35 run a greater risk than younger first-time mothers of suffering a psychosis in the months after delivery.

10 Feb 2009

First-time mothers at a greater risk of psychosis in the month following childbirth

A study of risk factors associated with psychotic illness after childbirth, published this week in the open-access journal PLoS Medicine, shows that first-time mothers are at the greatest risk of developing psychosis in the month following the birth of their child - even if they have never been treated in hospital for mental illness in the past.

10 Feb 2009

Older first time mothers more prone to develop mental illness

Swedish researchers have revealed that women who have their first baby after age 35 are more likely to develop a mental illness after the birth.

10 Feb 2009

Mum who tried to poison her children placed on good-behaviour bond

An Australian woman who tried to poison her two children last year has been placed on a good-behaviour bond after pleading guilty to the charge of intending to harm them.

10 Feb 2009

Volunteers needed for hydrocortisone in treatment resistant depression research

Can hydrocortisone, a drug which affects the body's stress system, help people with depression who do not respond to current treatments?

5 Feb 2009

Schizophrenia and bipolar disorder have same genetic causes

Schizophrenia and bipolar disorder have for decades been regarded as two distinct psychotic disorders when it comes to definitions and risk factors.

21 Jan 2009

Lack of grey matter linked to schizophrenia and bipolar disorder

A research study led by scientists from the Gregorio Marañón University Hospital in Madrid and the Network of Centres for Biomedical Research in Mental Health Networks (CIBERSAM) shows that adolescents experiencing a first outbreak of psychosis have lower levels of grey matter in their brains than healthy teenagers. Strangely, this change was seen in patients suffering from various psychoses, including bipolar illness and schizophrenia.

19 Jan 2009

Eli Lilly to pay $1.415 billion for off-label promotion of Zyprexa

American pharmaceutical giant Eli Lilly and Company today agreed to plead guilty and pay $1.415 billion for promoting its drug Zyprexa for uses not approved by the Food and Drug Administration (FDA), the Department of Justice announced today.

19 Jan 2009

Lilly receives complete response letter for Olanzapine LAI for treatment of schizophrenia

Eli Lilly and Company has announced that it received a complete response letter from the U.S. Food and Drug Administration (FDA) for olanzapine long-acting injection (LAI) for acute and maintenance treatment of schizophrenia in adults.

7 Jan 2009

Paliperidone palmitate shows positive results for treatment of schizophrenia

Paliperidone palmitate, an investigational long-acting therapy (LAT) demonstrated statistically significant symptom control compared with placebo according to the results of a 13-week study.

14 Dec 2008

Parkinson's disease can also affect changes in thought, behavior and judgment

Parkinson's disease affects 6.3 million people worldwide. While the disease is recognized for its profound effects on movement, up to 40 percent of Parkinson's disease patients also develop changes in thought, behavior and judgment.

14 Dec 2008

AstraZeneca and Targacept announce results from trial of AZD3480 for cognitive dysfunction in schizophrenia

AstraZeneca and Targacept, Inc. havey announced top-line results from a Phase IIb clinical trial of AZD3480 (TC-1734) conducted by AstraZeneca in cognitive dysfunction in schizophrenia (CDS), known as the HALO trial.

10 Dec 2008

New study focuses on adolescents and young adults at risk for psychosis

Emory University in Atlanta is playing a key role in the largest, most comprehensive study ever funded by the National Institute of Mental Health (NIMH) of adolescents and young adults at risk for developing a psychotic disorder.

12 Nov 2008

Research looks at differential rates of psychoses by ethnicity

Researchers examining the occurrence of psychoses among migrant groups have shown a raised incidence for all black and ethnic minority subgroups compared with white British counterparts, and reveal that the risk of psychoses for first and second generations varies by ethnicity.

5 Nov 2008

Rates of psychosis higher among minority groups in Britain

Both first- and second-generation immigrants to the United Kingdom appear to have a higher risk of psychoses than white British individuals, according to a report in the November issue of Archives of General Psychiatry , one of the JAMA/Archives journals.

4 Nov 2008

Worries over test for mad cow disease

A new test to screen blood for the incurable human form of mad cow disease could be available within 18 months, but it has raised concerns.

21 Oct 2008

Drugs to treat ADHD should be a last resort

According to new guidelines in Britain on attention deficit hyperactivity disorder (ADHD), drugs should be the last resort in treating the disorder and parents need to learn how to cope with their child's unruly behaviour.

24 Sep 2008