Signaling Pathway News and Research

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Hyperactive signaling pathway blocks cell division in the aging brain

Scientists from Basel have investigated the activity of stem cells in the brain of mice and discovered a key mechanism that controls cell proliferation.

29 Aug 2019

New study helps explain why lung tumors turn aggressive

Lung cancer is the number 1 killer among cancers, especially when it is of the non-small cell type. Among these, adenocarcinomas are the most common and aggressive type. These tumors also show a strong tendency to show dedifferentiation, or loss of the features that characterize a mature lung cell.

28 Aug 2019

New cellular processes controlling the formation of lymphatic valves found

Lymphedema, resulting from a damaged lymphatic system, can be a debilitating disease in which excess protein-rich fluid (lymph) collects in soft tissues and causes swelling -- most often in the arms or legs.

28 Aug 2019

Scientists reveal cancer cells' immune weak spot

Scientists have found a vulnerability in cancer cells that could make them more susceptible to being destroyed by the immune system, according to a new report in eLife.

27 Aug 2019

U of T scientists create antibodies with enormous potential for regenerative medicine

Our body makes antibodies to fight infections. But the synthetic versions of these molecules could hold the key to stimulating the body's ability to regenerate.

27 Aug 2019

Ketogenic diet shown to support intestinal stem cells

Scientists have discovered that ketone bodies produced during the ketogenic diet trigger the proliferation of intestinal stem cells in adults.

26 Aug 2019

Ohio University scientists win $1.7 million grant for research on non-melanoma skin cancers

The National Institute of Environmental Health Sciences has awarded Ohio University scientists Shiyong Wu and Lingying Tong a five-year $1.7 million grant to advance research on a potential prevention and treatment for non-melanoma skin cancers.

20 Aug 2019

Researchers identify compounds that influence time to sexual maturity and lifespan

Every day, people are exposed to myriad chemicals, both natural and synthetic. Some of these compounds may affect human physical development, but testing them directly on people would be grossly unethical.

20 Aug 2019

Study: Blocking inflammatory pathway could prevent melanoma brain metastasis

Brain metastases are among the deadliest tumor metastases, with a median survival period of less than one year, and the incidence of brain metastasis is rising.

20 Aug 2019

Study uncovers potential new treatment approach for lung cancer

Lung cancer is the second most common cancer found in both men and women. It is estimated there will be roughly 228,000 new lung cancer cases this year, and nearly 30% of those patients will have mutations in the KRAS pathway.

19 Aug 2019

Lipid signaling pathway may enhance T cell-mediated immunotherapy

The immune system surveils our body looking for things that don't belong, often bacteria and viruses. While cancer cells are abnormal cells that undergo unregulated cell growth, they are good at evading detection by the immune system.

19 Aug 2019

SLU researchers receive $2.1 million to find non-addictive pain medications

Neuropathic pain affects between 15 and 20 million people in the U.S. This type of pain can occur after injuries to the nervous system due to trauma, disease or exposure to neurotoxins, including after chemotherapy.

19 Aug 2019

Fruit fly model for studying diseases like gout, kidney stones reveals new drug targets

A new fruit fly model that mimics diseases associated with high uric acid levels, such as gout and kidney stones, has revealed new targets for developing treatments for these diseases.

From PLOS ONE 16 Aug 2019

Resurrecting protein ancestors yields evolutionary insights into their role in human cells

"Resurrecting" the ancestors of key proteins yields evolutionary insights into their role in human cells and in most cancers, a new study finds.

14 Aug 2019

Researchers examine how superbug fights last-resort antibiotics

Antibiotic resistance is one of the biggest threats to global health, food security, and development today. A new study shows how superbugs adapt to combat 'last-resort antibiotics'.

13 Aug 2019

Study shows potential of crucial signaling pathway as biomarker, therapeutic target for cancer

A crucial signaling pathway that can tell the immune system to fight off cancer can also be co-opted by cancer cells to put the brakes on the immune system, according to a new study from researchers in the Abramson Cancer Center at the University of Pennsylvania.

9 Aug 2019

Research offers molecular details of pancreatic cancer's ability to invade and evade

Two known gene mutations induce pathways that enhance pancreatic cancer's ability to invade tissues and evade the immune system.

6 Aug 2019

Discovery of distinct lung cancer pathways could help future patients

Known for its poor prognosis, lung adenocarcinoma is the most common type of lung cancer, responsible for about 4 of 10 diagnoses, according to the National Cancer Institute.

2 Aug 2019

Marshall University scientist wins new NIH grant for research on heart attack

Sandrine Pierre, Ph.D., associate scientific director at the Marshall Institute for Interdisciplinary Research, has received a new grant from the National Institutes of Health to further her research on myocardial infarction, known as a heart attack.

18 Jul 2019

Four young scientists receives Damon Runyon-Sohn Pediatric Cancer Fellowship Award

The Damon Runyon Cancer Research Foundation has named four outstanding young scientists as recipients of the prestigious Damon Runyon-Sohn Pediatric Cancer Fellowship Award, committing nearly $1 million to help address a critical shortage of funding for pediatric cancer research.

17 Jul 2019

Signaling Pathway News and Research

Hyperactive signaling pathway blocks cell division in the aging brain

New study helps explain why lung tumors turn aggressive

New cellular processes controlling the formation of lymphatic valves found

Scientists reveal cancer cells' immune weak spot

U of T scientists create antibodies with enormous potential for regenerative medicine

Ketogenic diet shown to support intestinal stem cells

Ohio University scientists win $1.7 million grant for research on non-melanoma skin cancers

Researchers identify compounds that influence time to sexual maturity and lifespan

Study: Blocking inflammatory pathway could prevent melanoma brain metastasis

Study uncovers potential new treatment approach for lung cancer

Lipid signaling pathway may enhance T cell-mediated immunotherapy

SLU researchers receive $2.1 million to find non-addictive pain medications

Fruit fly model for studying diseases like gout, kidney stones reveals new drug targets

Resurrecting protein ancestors yields evolutionary insights into their role in human cells

Researchers examine how superbug fights last-resort antibiotics

Study shows potential of crucial signaling pathway as biomarker, therapeutic target for cancer

Research offers molecular details of pancreatic cancer's ability to invade and evade

Discovery of distinct lung cancer pathways could help future patients

Marshall University scientist wins new NIH grant for research on heart attack

Four young scientists receives Damon Runyon-Sohn Pediatric Cancer Fellowship Award

Industry Focus eBook - Analytical Chemistry (2nd Edition) eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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