Protein C News and Research

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Researchers visualize protein machinery of respiration for the first time

Oxygen and sugar are the basis of life for animals, plants, fungi and many bacteria. The metabolic process called respiration makes it possible to convert food into energy for the cells.

31 Jan 2022

Preliminary study assesses durability of NAb titers against Omicron after mRNA-1273 booster

Researchers from Moderna, the developers of one key vaccine, have been investigating its ability to protect against the Omicron variant.

31 Jan 2022

Growth factor can powerfully counter the harmful effects of inflammatory bowel disease

A growth factor protein produced by rare immune cells in the intestine can protect against the effects of inflammatory bowel disease (IBD), according to a new discovery from Weill Cornell Medicine researchers.

31 Jan 2022

Placental ACE2 shedding may block SARS-CoV-2 transmission to babies during pregnancy

While COVID-19 disease significantly impacts many pregnant women, the rates of transmission from mother to baby in pregnancy are very low.

31 Jan 2022

New approach to make RNA vaccines easier to swallow

Like most vaccines, RNA vaccines have to be injected, which can be an obstacle for people who fear needles. Now, a team of MIT researchers has developed a way to deliver RNA in a capsule that can be swallowed, which they hope could help make people more receptive to them.

31 Jan 2022

Combined strategy suppresses the growth of deadly brain tumor

Short bursts of radiation therapy dramatically enhanced the efficiency of targeting glioblastomas with natural nanoparticle-based immunotherapy, thus suppressing growth of the deadly tumor, inducing anti-tumor immunity and prolonging survival in animal models, a research team at Massachusetts General Hospital has discovered.

31 Jan 2022

MCL1 regulates neuronal autophagy, cell survival in Alzheimer's disease

Announcing a new review article publication for Acta Materia Medica journal. In this review article, the authors discuss the emerging neuroprotective function of MCL1 and how dysregulation of MCL1 signaling is involved in the pathogenesis of AD.

31 Jan 2022

Drugs derived from activated protein C may limit ischemia and reperfusion injury, study suggests

A University of South Florida Health preclinical study offers molecular insight into how activated protein C (APC) may improve aging patients' tolerance to reperfusion injury – a potentially adverse effect of treatment for ischemic heart disease.

31 Jan 2022

Research shows rapid antigen tests can detect SARS-CoV-2 variants, including Omicron

Researchers determined the analytical sensitivity of a CE-marked fast antigen with the SARS-CoV-2 Omicron, Delta, Alpha, and Gamma variants.

31 Jan 2022

Researchers identify genetic cause of rare interstitial lung disease in a young child

New research from Washington University School of Medicine in St. Louis has solved the medical mystery of why a 2-year-old child — seemingly healthy at birth — succumbed to an undiagnosed, rare illness.

31 Jan 2022

Study identifies drugs that could help combat mortality in patients with COVID-19

Inflammation is a defense mechanism of the body to fight pathogens. However, when it is widespread and excessive, it can aggravate the pathology and even cause death.

31 Jan 2022

Yellow fever vaccine-vectored YF-S0 as a potent COVID-19 vaccine candidate

In a new study, a team of researchers developed YF-S0, an exceptionally potent COVID-19 vaccine candidate using live-attenuated yellow fever vaccine YF17D as a vector.

31 Jan 2022

Study reveals potential mechanism for iron accumulation in the aging brain

Breakdowns in regulatory mechanisms cause iron to build up in the brain as organisms grow older, increasing oxidative stress and causing cellular damage, according to a Northwestern Medicine study published in the journal eLife.

31 Jan 2022

3C-like protease inhibitor clinical candidate, S-217622, as a treatment for SARS-CoV-2

In a new study, a team of researchers discovered S-217622, a non-covalent SARS-CoV-2 3C-like protease (3CLpro) inhibitor clinical candidate for the treatment of COVID-19.

31 Jan 2022

Three exposures to SARS-CoV-2 spike protein can induce robust neutralizing antibodies against variants

In a new study, scientists revealed that three consecutive exposures SARS-CoV-2 spike protein through infection, vaccination, or both can induce strong neutralizing antibodies against a wide variety of viral variants, including omicron.

31 Jan 2022

Researchers create model to predict COVID-19 mortality

In a new study, researchers have created a model that can help determine the outcome of COVID-19 infection in patients in the ICU.

31 Jan 2022

It’s Day 6 of covid, and a rapid antigen test comes back positive. stay home, say virologists.

What does it mean if a person's rapid antigen test result comes back positive after five days of isolation due to covid-19? According to the experts, that person is most likely still carrying a viral load high enough to infect others.

31 Jan 2022

New AI technology could help reduce malnutrition in long-term care homes

New technology could help reduce malnutrition and improve overall health in long-term care homes by automatically recording and tracking how much food residents consume.

31 Jan 2022

Prion-like domains in SARS-CoV-2 RBD and ACE2 play important functional roles in viral adhesion and entry

Scientists have recently detected and analyzed viral PrDs in the S protein of SARS-CoV-2, which are the novel regulators of virion assembly.

31 Jan 2022

Vaccine hypersensitivity in children

A new paper published in Pediatric Allergy and Immunity provides a useful overview of such reactions in relation to pediatric vaccines.

31 Jan 2022

Protein C News and Research

Researchers visualize protein machinery of respiration for the first time

Preliminary study assesses durability of NAb titers against Omicron after mRNA-1273 booster

Growth factor can powerfully counter the harmful effects of inflammatory bowel disease

Placental ACE2 shedding may block SARS-CoV-2 transmission to babies during pregnancy

New approach to make RNA vaccines easier to swallow

Combined strategy suppresses the growth of deadly brain tumor

MCL1 regulates neuronal autophagy, cell survival in Alzheimer's disease

Drugs derived from activated protein C may limit ischemia and reperfusion injury, study suggests

Research shows rapid antigen tests can detect SARS-CoV-2 variants, including Omicron

Researchers identify genetic cause of rare interstitial lung disease in a young child

Study identifies drugs that could help combat mortality in patients with COVID-19

Yellow fever vaccine-vectored YF-S0 as a potent COVID-19 vaccine candidate

Study reveals potential mechanism for iron accumulation in the aging brain

3C-like protease inhibitor clinical candidate, S-217622, as a treatment for SARS-CoV-2

Three exposures to SARS-CoV-2 spike protein can induce robust neutralizing antibodies against variants

Researchers create model to predict COVID-19 mortality

It’s Day 6 of covid, and a rapid antigen test comes back positive. stay home, say virologists.

New AI technology could help reduce malnutrition in long-term care homes

Prion-like domains in SARS-CoV-2 RBD and ACE2 play important functional roles in viral adhesion and entry

Vaccine hypersensitivity in children

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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