Neuroscience News and Research

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Stroke survivors with depression more likely to die

People who are depressed after a stroke may have a tripled risk of dying early and four times the risk of death from stroke than people who have not experienced a stroke or depression, according to a study that will be presented at the American Academy of Neurology's 65th Annual Meeting in San Diego, March 16 to 23, 2013.

16 Jan 2013

Elan, Biogen Idec submit applications to FDA and EMA for updation of TYSABRI labels

Today Biogen Idec and Elan Corporation, plc announced that they have submitted applications to the U.S. Food and Drug Administration (FDA) and European Medicines Agency (EMA) requesting updates to the TYSABRI (natalizumab) labels.

16 Jan 2013

People with early Parkinson's frequently experience many non-motor symptoms

While movement problems are the main symptom of Parkinson's disease, a new study shows that even early in the course of disease people frequently experience many non-motor symptoms such as drooling, anxiety and constipation.

16 Jan 2013

Vanderbilt University, AstraZeneca partner to identify candidate drugs for major brain diseases

Today, AstraZeneca and Vanderbilt University announced they have signed a research collaboration agreement to identify candidate drugs aimed at treating psychosis and other neuropsychiatric symptoms associated with major brain diseases such as Alzheimer's disease and schizophrenia.

16 Jan 2013

Patients with Parkinson's develop artistic talents after dopamine-inducing therapy

Parkinson's experts across the world have been reporting a remarkable phenomenon - many patients treated with drugs to increase the activity of dopamine in the brain as a therapy for motor symptoms such as tremors and muscle rigidity are developing new creative talents, including painting, sculpting, writing, and more.

16 Jan 2013

Study explains how Timothy syndrome mutation causes wiring defects that underlie cognition

A new finding in neuroscience for the first time points to a developmental mechanism linking the disease-causing mutation in an autism-related disorder, Timothy syndrome, and observed defects in brain wiring, according to a study led by scientist Ricardo Dolmetsch and published online yesterday in Nature Neuroscience.

16 Jan 2013

Off-label drug ineffective in frontotemporal dementia

A randomized, controlled trial has dashed hopes that memantine therapy could benefit patients with frontotemporal dementia.

14 Jan 2013

Cancer researchers solve mystery of how Chd5 protein exerts its beneficial effects

A team of cancer researchers at Cold Spring Harbor Laboratory (CSHL) has solved the mystery of how one of the most powerful of the body's natural tumor-suppressing proteins, called Chd5, exerts its beneficial effects.

11 Jan 2013

Results from Morphotek’s farletuzumab Phase III combination study on ovarian cancer

Morphotek Inc., a wholly-owned subsidiary of Eisai Inc., announced today top-line results from a Phase III study of its investigational agent farletuzumab (MORAb-003) in combination with carboplatin and a taxane in patients with platinum-sensitive epithelial ovarian cancer in first relapse.

11 Jan 2013

Saliva gland test shows promise for Parkinson's

New research suggests that testing a portion of a person's saliva gland may be a way to diagnose Parkinson's disease.

11 Jan 2013

Apparent stem cell transplant success in mice may hold promise for people with ALS

Apparent stem cell transplant success in mice may hold promise for people with amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease.

11 Jan 2013

LM11A-31 effective at improving limb movement after spinal cord injury in mice

An experimental oral drug given to mice after a spinal cord injury was effective at improving limb movement after the injury, a new study shows.

10 Jan 2013

Bilingual older people reap neural rewards

Older bilingual people are faster than their monolingual peers in switching from one task to another, show researchers.

9 Jan 2013

Dopamine-related drug exposure, Parkinson's increase risk of impulse control problems

Parkinson's disease itself does not increase the risk of impulse control problems such as compulsive gambling and shopping that have been seen in people taking certain drugs for Parkinson's disease, according to new research published in the January 8, 2013, print issue of Neurology, the medical journal of the American Academy of Neurology.

9 Jan 2013

Beta blockers can reduce risk of Alzheimer's, other types of dementia

People taking the blood pressure drugs called beta blockers may be less likely to have changes in the brain that can be signs of Alzheimer's disease and other types of dementia, according to a study released today that will be presented at the American Academy of Neurology's 65th Annual Meeting in San Diego, March 16 to 23, 2013.

9 Jan 2013

Insect research yields insights for muscle control and nerve disorders in mammals

Working with fruit flies, Johns Hopkins scientists have decoded the activity of protein signals that let certain nerve cells know when and where to branch so that they reach and connect to their correct muscle targets. The proteins' mammalian counterparts are known to have signaling roles in immunity, nervous system and heart development, and tumor progression, suggesting broad implications for human disease research.

9 Jan 2013

Researchers deploy sensitive brain-testing methods on injured high school athletes

The ability to focus and switch tasks readily amid distractions was compromised for up to two months following brain concussions suffered by high school athletes, according to a study at the University of Oregon.

9 Jan 2013

Merck’s resubmission of the NDA for suggammadex sodium injection accepted for review by the FDA

Merck (NYSE: MRK), known as MSD outside the United States and Canada, today announced that the resubmission of the New Drug Application (NDA) for sugammadex sodium injection has been accepted for review by the U.S. Food and Drug Administration (FDA). Merck expects the FDA’s review to be completed in the first half of 2013.

7 Jan 2013

Study investigates prolonged pathological outcomes of traumatic brain injury

Researchers from the University of South Florida and colleagues at the James A. Haley Veterans' Hospital studying the long-term consequences of traumatic brain injury using rat models, have found that, overtime, TBI results in progressive brain deterioration characterized by elevated inflammation and suppressed cell regeneration.

7 Jan 2013

Researchers discover new pathway to reduce paradoxical pain

For individuals with agonizing pain, it is a cruel blow when the gold-standard medication actually causes more pain. Adults and children whose pain gets worse when treated with morphine may be closer to a solution, based on research published in the January 6 on-line edition of Nature Neuroscience.

7 Jan 2013

Neuroscience News and Research

Stroke survivors with depression more likely to die

Elan, Biogen Idec submit applications to FDA and EMA for updation of TYSABRI labels

People with early Parkinson's frequently experience many non-motor symptoms

Vanderbilt University, AstraZeneca partner to identify candidate drugs for major brain diseases

Patients with Parkinson's develop artistic talents after dopamine-inducing therapy

Study explains how Timothy syndrome mutation causes wiring defects that underlie cognition

Off-label drug ineffective in frontotemporal dementia

Cancer researchers solve mystery of how Chd5 protein exerts its beneficial effects

Results from Morphotek’s farletuzumab Phase III combination study on ovarian cancer

Saliva gland test shows promise for Parkinson's

Apparent stem cell transplant success in mice may hold promise for people with ALS

LM11A-31 effective at improving limb movement after spinal cord injury in mice

Bilingual older people reap neural rewards

Dopamine-related drug exposure, Parkinson's increase risk of impulse control problems

Beta blockers can reduce risk of Alzheimer's, other types of dementia

Insect research yields insights for muscle control and nerve disorders in mammals

Researchers deploy sensitive brain-testing methods on injured high school athletes

Merck’s resubmission of the NDA for suggammadex sodium injection accepted for review by the FDA

Study investigates prolonged pathological outcomes of traumatic brain injury

Researchers discover new pathway to reduce paradoxical pain

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Evaluating new approaches for rare disease genomics

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Advancing Intracellular Delivery with LumiPore®

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