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Previously unknown family of plague virulence factors identified

Researchers at Duke University Medical Center have identified a previously unknown family of virulence factors that make the bacterium responsible for the plague especially efficient at killing its host.

28 Aug 2005

Genomics reveals mechanisms that engineer remarkable heat resistance in bacteria

Warm-blooded creatures maintain a relatively stable body temperature that cannot tolerate the stress of intense heat (or cold). When it's too hot proteins destabilize and degrade--in some cases, with fatal results.

24 Aug 2005

First study to test the role of RNA chemical modifications on immunity

The investigators published their findings in the August issue of Immunity. "We think this study will open a new area of research in understanding how our immune systems protect us," says Weissman.

23 Aug 2005

Elderly woman latest victim of swine flu in Hong Kong

The Hong Kong government has reported that an elderly woman has contracted the pig-borne bacterial disease that has killed nearly 40 people in mainland China.

22 Aug 2005

$Propofol is a safe and effective drug to treat children with refractory status epilepticus$

Propofol is a safe and effective drug to treat children with refractory status epilepticus

...and it is recommended before thiopental, according to a study in the August 23, 2005 issue of Neurology, the scientific journal of the American Academy of Neurology. Propofol and thiopental are widely used intravenous anesthetics which are also known to help control seizures.

22 Aug 2005

Researchers test experimental drug Neuprex on infants undergoing heart surgery

UT Southwestern Medical Center is the only institution in the nation approved by the Food and Drug Administration to test an experimental drug on infants undergoing heart surgery to see whether it can help them avoid potentially lethal infections and improve survival.

22 Aug 2005

Japanese encephalitis in Indian province - update

Health officials say nine more people have now died from Japanese encephalitis in India's Uttar Pradesh state, taking the death toll from the mosquito-borne disease to 99.

22 Aug 2005

New phenomenon in which one bacterial cell can stop the growth of another on physical contact

Scientists have discovered a new phenomenon in which one bacterial cell can stop the growth of another on physical contact. The bacteria that stop growing may go into a dormant state, rather than dying. The findings have implications for management of chronic diseases, such as urinary tract infections.

22 Aug 2005

How some antibiotics kill bacteria

Researchers have uncovered how members of one family of antibiotics kill bacteria that make people sick.

11 Aug 2005

Expert warns of spread of Rocky Mountain Spotted Fever

An expert on infectious diseases at Johns Hopkins University School of Medicine, is warning that humans can inadvertently help spread infectious organisms beyond traditional state boundaries.

11 Aug 2005

No link between multiple vaccinations and infections

Over the years many concerns have been raised about chilhood vacinations, and one concern has been that multiple vaccinations 'use up' the immune system, so children are unable to fight off other illnesses.

10 Aug 2005

Biochemists reveal the first structural details of microcompartments

UCLA biochemists reveal the first structural details of a family of mysterious objects called microcompartments that seem to be present in a variety of bacteria. The discovery was published Aug. 5 in the journal Science.

10 Aug 2005

Findings do not support the hypothesis of increased risk of nontargeted infectious disease hospitalization after childhood vaccination

New research does not support a belief that children receiving multiple vaccines increase their risk of hospitalization for a nontargeted infectious disease, according to a study in the August 10 issue of JAMA: The Journal of the American Medical Association.

9 Aug 2005

Discovery may lead to new diagnostic tests for immunoglobulin A (IgA) deficiency and common variable immunodeficiency (CVID)

Defects in a single gene can result in two immune system disorders that leave affected individuals vulnerable to frequent or unusually severe infections, according to new findings reported in the August issue of Nature Genetics.

4 Aug 2005

Researchers characterize the proteome of the human cornea

In doing so, they have identified 141 distinct proteins, 99 of which had not been previously recognized in mammalian corneas. The details of their findings appear in the August/September issue of Molecular and Cellular Proteomics, an American Society for Biochemistry and Molecular Biology journal.

1 Aug 2005

Heparinase I is not a suitable replacement for protamine

The results of an international clinical trial led by Duke University Medical Center researchers has shown that a new drug is not a suitable replacement for protamine, a drug that has been used for more than 40 years after coronary artery bypass surgery to return thinned blood to its normal state.

1 Aug 2005

Controlling the expression of genes by turning them on or off could produce a drug for the treatment or cure of almost any disease

A new technique aimed at directly controlling the expression of genes by turning them on or off at the DNA level could lead to drugs for the treatment or cure of many diseases, say researchers at UT Southwestern Medical Center.

1 Aug 2005

Pseudomonas aeruginosa has broken the immune system's code

The human opportunistic pathogen, Pseudomonas aeruginosa, has broken the immune system's code, report researchers from the University of Chicago, enabling the bacteria to recognize when its host is most vulnerable and to launch an attack before the weakened host can muster its defenses.

1 Aug 2005

Two studies reveal how plague disables immune system

Two studies by researchers at the University of Chicago show how the bacteria that cause the plague manage to outsmart the immune system and how, by slightly altering one of the microbe's tools, the researchers produced what may be the first safe and effective vaccine.

1 Aug 2005

U.S. beaches getting dirtier and some are disappearing

The National Resources Defense Council (NRDC) has said this week that more and more U.S. beaches are being closed due to contamination, partly because there is more pollution and partly because of better monitoring.

31 Jul 2005