Liver News and Research

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Alcohol related liver problems on the rise among the young

According to the NHS figures there has been a huge increase in the number of young adults treated in hospital for serious liver problems brought on by drinking too much.

5 Dec 2011

Factors associated with increased risk of in-hospital falls after total hip or knee replacement surgery

Investigators from Hospital for Special Surgery have identified factors that are associated with an increased risk of in-hospital falls after total hip or knee replacement surgery.

5 Dec 2011

Growth hormone PDGF-BB and blood protein EPO implicated in development of cancer

Researchers at the Swedish medical university Karolinska Institutet have demonstrated that a growth hormone, PDGF-BB, and the blood protein EPO are involved in the development of cancer tumours and that they combine to help the tumours proliferate in the body.

5 Dec 2011

Novartis to showcase 160 presentations on breast cancer, hematological disease drugs at SABCS and ASH

Novartis Pharmaceuticals Corporation will showcase more than one hundred and sixty presentations on data from its robust oncology portfolio at two key medical congresses this month, demonstrating significant advances for patients with cancers and hematological diseases.

3 Dec 2011

La Jolla researchers create first cellular movies showing destruction underlying type 1 diabetes

A war is being waged in the pancreases of millions of people throughout the world. The siege leads to the development of type 1 diabetes and has been a battlefield largely hidden from view-- until now.

3 Dec 2011

Mainz gastroenterologist awarded ERC Advanced Grant

The European Research Council (ERC) has earmarked about €2.5 mio. to fund the research being conducted by gastroenterologist and biochemist Professor Dr. Dr. Detlef Schuppan at Mainz University Medical Center.

3 Dec 2011

New technique allows production of medically useful amounts of endoderm cells from human PSCs

Scientists in Canada have overcome a key research hurdle to developing regenerative treatments for diabetes and liver disease with a technique to produce medically useful amounts of endoderm cells from human pluripotent stem cells. The research, published in Biotechnology and Bioengineering, can be transferred to other areas of stem cell research helping scientists to navigate the route to clinical use known as the 'valley of death'.

3 Dec 2011

NIAAA awards Rutgers $10M grant to explore genetic links to alcoholism

Rutgers University Cell and DNA Repository (RUCDR) has received a $10 million grant from the National Institute on Alcohol Abuse and Alcoholism (NIAAA) to provide DNA extraction, basic genetic testing, and repository services for more than 46,000 saliva samples, in support of national research efforts to determine the genetic and environmental factors that lead to alcoholism.

3 Dec 2011

Baby boomers more likely to develop HCV

Experts at Montefiore Medical Center urge the general public to be tested for the Hepatitis C virus, especially baby boomers, adults born between 1946-1964, who could be most at risk for this disease. Baby boomers are more likely to have been exposed to dangerous risk factors decades ago, such as sharing a drug needle, being tattooed or pierced with unsterilized tools or receiving a tainted blood transfusion.

2 Dec 2011

Treatments for lymphoma with no side effects

Larry Conrad went in for his annual physical on his 50th birthday. During his exam, his doctor found swollen lymph nodes in his armpits and groin. Conrad had a cough and said he'd lost weight because he 'felt full all the time'. His doctor ordered a series of tests, and Conrad was diagnosed with Non-Hodgkin's lymphoma, the most common type.

2 Dec 2011

Specific electromagnetic fields can block cancer cell growth

New evidence by University of Alabama at Birmingham researchers that specific electromagnetic fields can safely block the proliferation of cancer cells and tumor growth may help refine a new, targeted therapy without any collateral damage.

2 Dec 2011

Two studies uncover limitations in screening for hepatocellular carcinoma

Two studies available in the December issue of Hepatology, a journal of the American Association for the Study of Liver Diseases, have uncovered limitations in screening for primary liver cancer, also known as hepatocellular carcinoma.

2 Dec 2011

EGCG may prevent HCV reinfection after liver transplantation

German researchers have determined that epigallocatechin-3-gallate (EGCG)—a flavonoid found in green tea—inhibits the hepatitis C virus (HCV) from entering liver cells.

1 Dec 2011

Immune system stimulant used as suppressor to treat chronic graft-versus-host disease

In a study that seems to pivot on a paradox, scientists at Dana-Farber Cancer Institute have used an immune system stimulant as an immune system suppressor to treat a common, often debilitating side effect of donor stem cell transplantation in cancer patients. The effect, in some cases, was profound.

1 Dec 2011

Removing amyloid beta can restore sense of smell in mouse model of Alzheimer's

One of the earliest known impairments caused by Alzheimer's disease - loss of sense of smell - can be restored by removing a plaque-forming protein in a mouse model of the disease, a study led by a Case Western Reserve University School of Medicine researcher finds.

30 Nov 2011

Ranbaxy receives FDA approval for first generic version of cholesterol-lowering drug Lipitor

The U.S. Food and Drug Administration today approved the first generic version of the cholesterol-lowering drug Lipitor.

30 Nov 2011

Combination treatment improves progression-free survival in pancreatic neuroendocrine tumors

Combination treatment with everolimus, an inhibitor of the mammalian target rapamycin (mTOR), and octreotide has shown to improve progression-free survival for patients with advanced neuroendocrine tumors and a history of carcinoid syndrome, according to researchers at The University of Texas MD Anderson Cancer Center.

30 Nov 2011

ACGME approves Cedars-Sinai's neurology residency training program

The Accreditation Council for Graduate Medical Education has approved a neurology residency training program at Cedars-Sinai Medical Center. Recruitment of the first group of three residents is under way through the 2012 "match," a process in which an independent organization pairs applicants with programs to meet the preferences of each.

30 Nov 2011

Seizure drug slows spread of uveal melanoma

A drug commonly used to treat seizures appears to make eye tumors less likely to grow if they spread to other parts of the body, according to researchers at Washington University School of Medicine in St. Louis.

29 Nov 2011

Serotonin instructs scar forming cells to switch off regeneration in chronic liver disease

In liver disease, extent of tissue damage depends on the balance between the generation of scar tissue and the regeneration of new liver cells. In a significant minority of people who get injury to their organs instead of repairing them, they form scars.

29 Nov 2011

Liver News and Research

Alcohol related liver problems on the rise among the young

Factors associated with increased risk of in-hospital falls after total hip or knee replacement surgery

Growth hormone PDGF-BB and blood protein EPO implicated in development of cancer

Novartis to showcase 160 presentations on breast cancer, hematological disease drugs at SABCS and ASH

La Jolla researchers create first cellular movies showing destruction underlying type 1 diabetes

Mainz gastroenterologist awarded ERC Advanced Grant

New technique allows production of medically useful amounts of endoderm cells from human PSCs

NIAAA awards Rutgers $10M grant to explore genetic links to alcoholism

Baby boomers more likely to develop HCV

Treatments for lymphoma with no side effects

Specific electromagnetic fields can block cancer cell growth

Two studies uncover limitations in screening for hepatocellular carcinoma

EGCG may prevent HCV reinfection after liver transplantation

Immune system stimulant used as suppressor to treat chronic graft-versus-host disease

Removing amyloid beta can restore sense of smell in mouse model of Alzheimer's

Ranbaxy receives FDA approval for first generic version of cholesterol-lowering drug Lipitor

Combination treatment improves progression-free survival in pancreatic neuroendocrine tumors

ACGME approves Cedars-Sinai's neurology residency training program

Seizure drug slows spread of uveal melanoma

Serotonin instructs scar forming cells to switch off regeneration in chronic liver disease

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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