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Genetic biomarker test predicts how men with high-risk prostate cancer will respond to treatment

A new meta-analysis finds that a genetic biomarker test accurately predicts how men with high-risk prostate cancer will respond to treatment with radiation and hormone therapy.

25 Oct 2021

Study provides a specific target to tackle breast cancer relapse

Molecular targets for therapies that could prevent breast cancer recurrence have been identified by a group of German, Norwegian and British scientists who analyzed tumour cells that proved resistant to the original treatment.

25 Oct 2021

Development of light-based tool for the inactivation of SARS-CoV-2

Researchers from EMIT bio have developed a biological light unit that can sterilize surfaces, killing SARS-CoV-2.

25 Oct 2021

Men with Stage IV breast cancer who are receptive to systemic therapy benefit from surgery

Men with Stage IV breast cancer and known estrogen (ER) and progesterone receptor (PR) status benefit from surgical intervention and from trimodal therapy (systemic therapy, surgery, and radiation), according to a study presented at the virtual American College of Surgeons (ACS) Clinical Congress 2021.

25 Oct 2021

Cancer patients have impaired antibody responses to COVID-19 mRNA vaccines

A new study posted to the medRxiv* preprint server studies the neutralizing antibody response in cancer patients diagnosed with chronic lymphocytic leukemia (CLL), lung cancer, breast cancer, and various non-Hodgkin’s lymphomas (NHL), post-reception of two doses of messenger RNA (mRNA) vaccines.

25 Oct 2021

Molecular mechanism that controls the transition from acute to chronic pain revealed

A new study led by University of California, Irvine researchers is the first to reveal the specific molecular mechanism that controls the transition from acute to chronic pain, and identifies this mechanism as a critical target for disease-modifying medicines.

25 Oct 2021

Compared to influenza, COVID-19 is more likely to cause venous thrombosis

New research published in the medRxiv* preprint server suggests that COVID-19 illness incurs a greater 90-day risk of venous thrombosis than the flu. However, arterial thrombosis remains a higher risk among people with the influenza virus.

24 Oct 2021

Health care costs for people with rare diseases have been underestimated, study shows

A new, retrospective study of medical and insurance records indicates health care costs for people with a rare disease have been underestimated and are three to five times greater than the costs for people without a rare disease.

22 Oct 2021

Gene therapy strategy against Angelman syndrome shows early promise

Scientists at the UNC School of Medicine have reported in the journal JCI Insight encouraging early tests of a gene therapy strategy against Angelman syndrome, a neurodevelopmental disorder that features poor muscle control and balance, hard-to-treat epilepsy, and intellectual disabilities.

22 Oct 2021

Study shows immune profile heterogeneity amongst healthy adults

Researchers opted to use single-cell RNA-seq to observe single cells in detail as they encounter a specific antigen.

22 Oct 2021

SARS-CoV-2 cocktail with three antibodies potent in preclinical testing

Amidst growing concerns on the use and potential benefits of convalescent plasma therapy, a research group in the United States has identified three human antibodies (Abs) that, when combined, demonstrate both robust viral suppressive properties against all tested severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Variants of Concern (VoC) in vitro and profound antiviral efficacy in vivo.

22 Oct 2021

Expert sound alarm on the crisis in sex education across the U.S.

Experts at the Society for Adolescent Health and Medicine (SAHM) are calling attention to a crisis in sex education, specifically the continued creation and endorsement of abstinence-only curricula being taught across the U.S.

21 Oct 2021

Investigational inhaled COVID-19 treatment graduates to phase 3 in ACTIV-2 trial

The AIDS Clinical Trials Group, the largest global HIV research network, which recently expanded its focus to include evaluating outpatient treatment for COVID-19, today announced that the external data and safety monitoring board (DSMB) has recommended that SNG001, an inhaled formulation of interferon beta, advance to phase 3 in the ACTIV-2 Outpatient Monoclonal Antibodies and Other Therapies Trial (ACTG A5401).

21 Oct 2021

Influence of age on innate and adaptive immunity in COVID-19 patients

A new study investigates how age influences SARS-CoV-2 replication, innate and adaptive immune responses.

21 Oct 2021

$Extra dairy intake lowers risk of falls and fractures among older adults in residential care$

Extra dairy intake lowers risk of falls and fractures among older adults in residential care

Increasing intake of foods rich in calcium and protein such as milk, yogurt, and cheese, reduces falls and fractures in older adults living in residential care, finds a randomized controlled trial published by The BMJ today.

21 Oct 2021

Cell-free DNA can help detect measurable residual disease in children with medulloblastoma

Scientists at St. Jude Children's Research Hospital have shown that cell-free DNA from cerebrospinal fluid (CSF) can be used to detect measurable residual disease (MRD) in children treated for the brain tumor medulloblastoma.

21 Oct 2021

Study reveals dual role of anti-cancer inhibitor

TG2, an enzyme known to help cancers spread more quickly, also plays a role in regulating T-cells, according to a Northwestern Medicine study published in the Journal for Immunotherapy of Cancer.

21 Oct 2021

Novel Einstein-developed strategy successfully suppresses HIV infections in mice

Armed with a novel strategy they developed for bolstering the body's immune response, scientists at Albert Einstein College of Medicine have successfully suppressed HIV infections in mice - offering a path to a functional cure for HIV and other chronic viral infections.

21 Oct 2021

CAR-T cell treatment's efficacy in hematological malignancies predicted by epigenetics

One in five cancers affects blood cells and lymph nodes, causing leukemias and lymphomas, respectively. Although their treatment with drugs has led to a great advance in their cure, there are cases where there is no clinical response or resistance to them is generated.

21 Oct 2021

Immune responses to SARS-CoV-2 infection and vaccination in patients with multiple sclerosis

A new study has focused on the immune response in pwMS undergoing anti-CD20 treatment.

21 Oct 2021

Therapy News and Research

Genetic biomarker test predicts how men with high-risk prostate cancer will respond to treatment

Study provides a specific target to tackle breast cancer relapse

Development of light-based tool for the inactivation of SARS-CoV-2

Men with Stage IV breast cancer who are receptive to systemic therapy benefit from surgery

Cancer patients have impaired antibody responses to COVID-19 mRNA vaccines

Molecular mechanism that controls the transition from acute to chronic pain revealed

Compared to influenza, COVID-19 is more likely to cause venous thrombosis

Health care costs for people with rare diseases have been underestimated, study shows

Gene therapy strategy against Angelman syndrome shows early promise

Study shows immune profile heterogeneity amongst healthy adults

SARS-CoV-2 cocktail with three antibodies potent in preclinical testing

Expert sound alarm on the crisis in sex education across the U.S.

Investigational inhaled COVID-19 treatment graduates to phase 3 in ACTIV-2 trial

Influence of age on innate and adaptive immunity in COVID-19 patients

Extra dairy intake lowers risk of falls and fractures among older adults in residential care

Cell-free DNA can help detect measurable residual disease in children with medulloblastoma

Study reveals dual role of anti-cancer inhibitor

Novel Einstein-developed strategy successfully suppresses HIV infections in mice

CAR-T cell treatment's efficacy in hematological malignancies predicted by epigenetics

Immune responses to SARS-CoV-2 infection and vaccination in patients with multiple sclerosis

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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