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Later onset of puberty associated with malnutrition, earlier onset to childhood obesity

The timing of the onset of puberty is linked to levels of nutrition: later onset is associated with malnutrition, while earlier onset is linked to childhood obesity. A team of researchers, led by Carol Elias, at the University of Texas Southwestern Medical Center, Dallas, has now generated data in mice that run counter to current thinking about the molecular pathway by which nutrition status affects the onset of puberty. Further, the team defines a new regulatory pathway for the process, which, if confirmed in humans, could potentially lead to new approaches to treating disorders of puberty and fertility.

23 Dec 2010

Funding bill passed; Food safety measure sent to President; 9/11 worker legislation still held up

Although Congress gave approval to a short-term funding measure for the federal government, the bill doesn't contain money to pay for enforcement of new health law regulations. Meanwhile, work continued on other pending proposals.

23 Dec 2010

New study reveals statin therapy linked to reduced postoperative mortality

Statin drugs were first introduced to lower blood cholesterol concentrations; however, research is now discovering other benefits. A new study from France, published in the January 2011 issue of Anesthesiology, is the first to analyze the impact of preoperative chronic statin therapy on postoperative adverse events in surgical patients. Findings from the study suggest that statin therapy is associated with reduced postoperative mortality.

23 Dec 2010

mTORC1 cellular pathway affects aging phenotype

Whitehead Institute researchers have linked hyperactivity in the mechanistic target of rapamycin complex 1 (mTORC1) cellular pathway, to reduced ketone production, which is a well-defined physiological trait of aging in mice.

23 Dec 2010

TMEM106B gene appears to protect against frontotemporal lobar degeneration

Neuroscientists had assumed that a mutation in the progranulin gene, which makes the progranulin protein and supports brain neurons, was sufficient to produce a kind of dementia known as frontotemporal lobar degeneration. But now an international team of scientists led by researchers at Mayo Clinic's campus in Florida have found another genetic factor they say appears to protect against the disorder in progranulin mutation carriers.

23 Dec 2010

Gene changes during brain development can lead to male genitalia formation in female embryo

Australian scientists have discovered that changes to a gene involved in brain development can lead to testis formation and male genitalia in an otherwise female embryo.

22 Dec 2010

New research sheds light on how neurons make connections with one another

Newly published research led by Professor Z. Josh Huang, Ph.D., of Cold Spring Harbor Laboratory sheds important new light on how neurons in the developing brain make connections with one another.

22 Dec 2010

Verizon grants will eanble heart attack patients to receive life-saving treatments more quickly

Heart attack patients can receive life-saving treatments more quickly thanks to $100,000 in grants from the Verizon Foundation to the Foundation of UMDNJ for a program that enables heart attack patients to bypass the emergency room and go directly to the cardiac catheterization laboratory at UMDNJ-The University Hospital.

22 Dec 2010

Chronic fatigue syndrome not linked to virus

The latest research from the University College London, the Wellcome Trust Sanger Institute, and University of Oxford, England suggests that chronic fatigue syndrome (CFS) is not caused by the virus XMRV (xenotropic murine leukemia virus-related virus). The team says that earlier research that linked the virus to CFS was faulty because of contamination of mouse cell DNA samples in the laboratory.

21 Dec 2010

The Lewin Group to perform two-year study on health outcomes in children with ASD

The National Institute of Mental Health has selected The Lewin Group to perform a two-year study on health outcomes in children with autism and their families. The study will describe the range of medical conditions experienced by children with autism spectrum disorders and the health outcomes of the children and their families.

21 Dec 2010

DNA sequence variations linked with heart's electrical rhythm in several surprising regions

A study among almost 50,000 people worldwide has identified DNA sequence variations linked with the heart's electrical rhythm in several surprising regions among 22 locations across the human genome. The variants were found by an international consortium, including Johns Hopkins researchers, and reported Nov. 14 in the Nature Genetics advance online publication.

21 Dec 2010

New CPT code for use with T-SPOT.TB test

Oxford Immunotec, Inc. announces that a new and specific Current Procedural Terminology (CPT®) code has been established by the American Medical Association for use with the T-SPOT®.TB test. The new Category I code, 86481, is described as "Tuberculosis test, cell mediated immunity antigen response measurement; enumeration of gamma interferon-producing T-cells in cell suspension." This new code will be effective as of January 1, 2011.

21 Dec 2010

Clue to the blues that come with the flu

Vanderbilt University researchers may have found a clue to the blues that can come with the flu - depression may be triggered by the same mechanisms that enable the immune system to respond to infection.

21 Dec 2010

Study reveals nasal congestion can be a sign of severe asthma

Nasal congestion can be a sign of severe asthma, which means that healthcare professionals should be extra vigilant when it comes to nasal complaints. Furthermore, more severe asthma appears to be more common than previously thought, reveals a study from the Sahlgrenska Academy's Krefting Research Centre.

21 Dec 2010

Exome sequencing leads to correct diagnosis and life-saving treatment for mysterious genetic disorder

A genetic testing approach called exome sequencing—which provides a clinically practical alternative to whole-genome sequencing—led to correct diagnosis and life-saving treatment in a child with a previously unknown genetic disease, reports an upcoming paper in Genetics in Medicine, the official peer-reviewed journal of The American College of Medical Genetics (ACMG). The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

21 Dec 2010

Eating in front of computer linked to weight gain: Study

The latest study shows that having lunch in front of your computer may lead to more weight gain and increased snacking. The team from the University of Bristol was studying the ways in which memory and attention influence appetite.

20 Dec 2010

Exciting progress made in MS research during 2010

Exciting advances were made in 2010 in virtually every field of MS research. Progress toward finding new therapies for MS is illustrated by the availability of the first oral disease-modifying therapy for MS. Progress was also made toward finding ways to restore function and improving quality of life and specific MS symptoms through exercise, meditation, rehabilitation and medications, including the first therapy specifically approved to treat a symptom of MS (Ampyra).

20 Dec 2010

Scientists suggest targeting ion channels could offer effective pain relief

University at Buffalo neuroscience researchers conducting basic research on ion channels have demonstrated a process that could have a profound therapeutic impact on pain.

20 Dec 2010

Diagenic, Pfizer enter collaboration to identify biomarkers in early stages of Alzheimer's disease

DiaGenic ASA and Pfizer Inc today signed an agreement for explorative R&D collaboration to identify biomarkers in early stages of Alzheimer's disease (AD) using DiaGenic's patented gene expression technology and its blood samples from ongoing clinical studies.

17 Dec 2010

Study highlights death or rehospitalization rates for Medicare beneficiaries with ischemic stroke

Nearly two-thirds of Medicare beneficiaries discharged from hospitals after ischemic stroke die or are readmitted within one year, researchers report in Stroke: Journal of the American Heart Association.

17 Dec 2010

X linked News and Research

Later onset of puberty associated with malnutrition, earlier onset to childhood obesity

Funding bill passed; Food safety measure sent to President; 9/11 worker legislation still held up

New study reveals statin therapy linked to reduced postoperative mortality

mTORC1 cellular pathway affects aging phenotype

TMEM106B gene appears to protect against frontotemporal lobar degeneration

Gene changes during brain development can lead to male genitalia formation in female embryo

New research sheds light on how neurons make connections with one another

Verizon grants will eanble heart attack patients to receive life-saving treatments more quickly

Chronic fatigue syndrome not linked to virus

The Lewin Group to perform two-year study on health outcomes in children with ASD

DNA sequence variations linked with heart's electrical rhythm in several surprising regions

New CPT code for use with T-SPOT.TB test

Clue to the blues that come with the flu

Study reveals nasal congestion can be a sign of severe asthma

Exome sequencing leads to correct diagnosis and life-saving treatment for mysterious genetic disorder

Eating in front of computer linked to weight gain: Study

Exciting progress made in MS research during 2010

Scientists suggest targeting ion channels could offer effective pain relief

Diagenic, Pfizer enter collaboration to identify biomarkers in early stages of Alzheimer's disease

Study highlights death or rehospitalization rates for Medicare beneficiaries with ischemic stroke

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