HIV 1 News and Research

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Rifampin kinetics poor in children

Rifampin (RMP), a first-line antituberculosis drug, reaches serum concentrations well below suggested lower limits when a standard dose of 8-12mg/kg body weight is given to children.

22 Apr 2009

NanoBio starts clinical trial for adjuvanted intranasal flu vaccine

NanoBio has announced that the U.S. Food and Drug Administration (FDA) has approved the company's Investigational New Drug (IND) application for the Phase 1 clinical study of NB-1008, a seasonal influenza vaccine administered via a nasal dropper.

20 Apr 2009

Humanized mouse infected with HIV vaginally and rectally allows testing

The "humanized mouse" developed by Dr. J. Victor Garcia-Martinez has allowed the University of Texas Southwestern physician-scientist to conduct HIV/AIDS studies that would have been impossible without such a small animal model of HIV infection.

20 Apr 2009

GlaxoSmithKline and Pfizer team up to form HIV company

Pharmaceutical companies GlaxoSmithKline and Pfizer today announced an "innovative agreement" to pool their HIV assets creating a new world-leading, specialist HIV company.

16 Apr 2009

NIH grants will strengthen fight against HIV/AIDS-tuberculosis

The Fogarty International Center of the National Institutes of Health today announced it will award $11.75 million over five years in grants to institutions to strengthen the fight against HIV/AIDS and tuberculosis in Haiti, Uganda and China and establish a new program in Tanzania.

16 Apr 2009

New updated clinical guidelines for HIV-associated opportunistic infections

The first complete update in five years of the U.S. guidelines for preventing and treating HIV-associated opportunistic infections has been released by the National Institutes of Health and the Centers for Disease Control and Prevention in cooperation with the HIV Medicine Association of the Infectious Diseases Society of America (IDSA).

16 Apr 2009

Tijuana injection drug users on collision course for HIV and tuberculosis

A study by researchers from the University of California, San Diego School of Medicine, in collaboration with Mexican researchers and health officials, shows that as many as 67 percent of injection drug users in Tijuana test positive for tuberculosis (TB) infection.

15 Apr 2009

Discovery of a new target for novel HIV treatment strategy

The AIDS-causing HIV specifically counteracts the mechanisms of human cells that protect these against viral infections - a special viral protein marks protective cellular proteins for their rapid destruction and thus diminishes the cell's supply.

15 Apr 2009

Early HIV treatment decreases the risk of death

Begin treatment as early as possible: this general common sense rule seems to apply to most diseases except HIV-AIDS, which is only treated once a certain number of immune cells called "CD4+" cells have disappeared.

14 Apr 2009

New AIDS research training grants awarded for projects in 15 countries

The Fogarty International Center of the National Institutes of Health has awarded seven grants totaling almost $2.7 million to train HIV/AIDS researchers in 15 low- and middle-income countries.

14 Apr 2009

HIV infection rates are lower in circumcised heterosexual men

Three recent African trials support male circumcision for reducing the risk of contracting HIV in heterosexual men.

14 Apr 2009

Mutations that help HIV hide undermine the virus's ability to replicate

When HIV infects a cell, a complex of human immune proteins called HLA (short for human leukocyte antigen) alert killer T cells by displaying bits of the virus on the surface of the cell. The T cells recognize these HIV fragments and mobilize an attack.

13 Apr 2009

Gene targeting discovery opens door for vaccines and drugs

In a genetic leap that could help fast track vaccine and drug development to prevent or tame serious global diseases, DMS researchers have discovered how to destroy a key DNA pathway in a wily and widespread human parasite.

13 Apr 2009

Safety of Bitter orange herbal weight loss product questioned

The Australian Therapeutic Goods Administration (TGA) is reportedly examining whether there are any risks associated with an over-the-counter (OTC) herbal weight loss programme sold in Australia.

13 Apr 2009

Early administration of HIV antiretroviral therapy improves survival

The first antiretroviral treatments appeared in 1996. Since then, new and better drugs have been discovered that have almost turned AIDS into a chronic disease.

12 Apr 2009

Rural AIDS and HIV expert comments on media campaign

A recent study revealed that the public's concern about the HIV/AIDS problem in the United States has lessened: In 1995, 44 percent of people surveyed considered HIV/AIDS the most urgent health problem, but only 5 percent of study participants reported feeling this way today, said William L. Yarber, senior director of the Rural Center for AIDS/STD Prevention at Indiana University.

9 Apr 2009

Youth as young as 12 engaging in risky sexual activity

Middle school youth are engaging in sexual intercourse as early as age 12, according to a study by researchers at The University of Texas School of Public Health.

9 Apr 2009

HIV virus may have become more virulent

Damage to patients' immune systems is happening sooner now than it did at the beginning of the HIV epidemic, suggesting the virus has become more virulent, according to a new study in the May 1, 2009 issue of Clinical Infectious Diseases, now available online.

8 Apr 2009

AIDS organizations endorse new HIV testing bill

Five AIDS service organizations have endorsed legislation proposed by State Senate Health Committee Chair Thomas Duane that would bring New York's HIV counseling and testing law up-to-date with the realities facing the epidemic today.

8 Apr 2009