Neuroscience News and Research

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USF Health sponsors conference on Parkinson's disease and multiple sclerosis

Some of the country's leading physicians and researchers in the fields of Parkinson's disease and multiple sclerosis will gather later this month to discuss the latest advances in the diagnosis and treatment of these neurological disorders.

3 Feb 2011

Coordinated behavior occurs whether or not neurons are actually connected via synapses

The brain-awake and sleeping-is awash in electrical activity, and not just from the individual pings of single neurons communicating with each other. In fact, the brain is enveloped in countless overlapping electric fields, generated by the neural circuits of scores of communicating neurons.

3 Feb 2011

Concert and WRAIR enter CRADA to evaluate novel compound for seizure protection associated with TBI

Concert Pharmaceuticals, Inc. today announced that it has entered into a Cooperative Research and Development Agreement with the Walter Reed Army Institute of Research. The CRADA will allow the WRAIR to conduct preclinical testing on a novel compound derived from Concert's DCE Platform™ (deuterated chemical entity platform) for seizure protection associated with traumatic brain injury, a major public health concern.

3 Feb 2011

HealthCore, AstraZeneca collaborate to conduct real-world studies on disease states, treatment

AstraZeneca Pharmaceuticals LP and HealthCore, the health outcomes research subsidiary of WellPoint, today announced a collaborative agreement to conduct real-world studies designed to determine how to most effectively and economically treat disease.

3 Feb 2011

ImmunoCellular Therapeutics initiates enrollment in ICT-107 Phase II trial for GBM

ImmunoCellular Therapeutics, Ltd., a biotechnology company that is developing immune-based therapies for the treatment of various forms of cancer, announced today that the first patient has been enrolled in its Phase II trial of ICT-107 at the New Jersey Neuroscience Institute at JFK Medical Center. ICT-107 is the company's dendritic cell based cancer vaccine candidate for the treatment of glioblastoma multiforme (GBM).

3 Feb 2011

Ritalin may help improve brain function in children with iron deficiency

Ritalin may help improve brain function in adolescent rats that were iron deficient during infancy, according to a team of Penn State neuroscientists. This may have implications for iron-deficient human infants as well.

3 Feb 2011

International scientist team identifies gene mutation strongly linked to schizophrenia

In a major advance for schizophrenia research, an international team of scientists, led by Jonathan Sebat, PhD, assistant professor of psychiatry and cellular and molecular medicine at the University of California, San Diego School of Medicine, has identified a gene mutation strongly linked to the brain disorder - and a signaling pathway that may be treatable with existing compounds.

3 Feb 2011

Malarial drugs may help treat specific form of frontotemporal dementia

Frontotemporal dementia is caused by a breakdown of nerve cells in the frontal and temporal region of the brain, which leads to, among other symptoms, a change in personality and behavior. The cause of some forms of frontotemporal dementia is a genetically determined reduction of a hormone-like growth factor, progranulin.

3 Feb 2011

Older people with metabolic syndrome may face high risk of developing memory loss

Older people with larger waistlines, high blood pressure and other risk factors that make up metabolic syndrome may be at a higher risk for memory loss, according to a study published in the February 2, 2011, online issue of Neurology, the medical journal of the American Academy of Neurology.

3 Feb 2011

New study to address causes and risk factors of ovarian cancer in African American women

University Hospitals Case Medical Center and Case Western Reserve University School of Medicine are conducting an important new study addressing the lack of knowledge about causes and risk factors for ovarian cancer in African American women. The five-year study is funded by the National Cancer Institute through Case Western Reserve University School of Medicine.

2 Feb 2011

FDA issues Complete Response Letter for approval of Eisai's rabeprazole sodium extended-release capsules

Eisai announced today that the company received a Complete Response Letter from the United States Food and Drug Administration (FDA) regarding the New Drug Application (NDA) of rabeprazole sodium extended-release capsules, 50 mg, an investigational proton pump inhibitor (PPI) under review for the healing and long-term maintenance of healing and symptom resolution of erosive gastroesophageal reflux disease (GERD), and for the treatment of daytime and nighttime heartburn and other symptoms of non-erosive GERD.

2 Feb 2011

Defective nucleoli linked to Parkinson's disease

"Nucleolus", or small nucleus, is the term coined by early biologists for the tiny structure within the nucleus which they saw under the microscope. In this structure within the nucleus, RNA molecules and proteins are assembled to form ribosomes, the true protein factories of cells.

2 Feb 2011

Drugs affecting brain noradrenaline levels could improve breathing in sleep apnea patients

New research from the University of Toronto could provide some restful nights for the 18 million North Americans who suffer from obstructive sleep apnea.

2 Feb 2011

Research discovers new role of TRPV1 receptors in regulation of locomotor activity

Research by a Barrow Neurological Institute scientist on the thermoregulatory effects of a receptor more commonly studied for its role in pain is the cover story in the Feb. 2 issue of the Journal of Neuroscience.

2 Feb 2011

Specific brain network acts as event monitoring system

Wouldn't life be easy if everything happened as we anticipated? In reality, our brains are able to adapt to the unexpected using an inbuilt network that makes predictions about the world and monitors how those predictions turn out.

1 Feb 2011

Widespread screening or ultrasound for blocked neck arteries not necessary to determine stroke risk

Widespread screening or routine ultrasound for blocked neck arteries to determine stroke risk isn't necessary, according to new guidelines from the American Heart Association/American Stroke Association, American College of Cardiology and other groups.

1 Feb 2011

Walk briskly to boost memory

Researchers have found that older adults who took a brisk walk three times a week did better on memory tests and increased the size of their hippocampus, a portion of the brain involved with memory formation.

1 Feb 2011

Brain scans can predict smokers' behavior change: New study

Brain scans showing neural reactions to pro-health messages can predict if you'll keep that resolution to quit smoking more accurately than you yourself can. That's according to a new study forthcoming in Health Psychology, a peer-reviewed journal.

1 Feb 2011

Physicians suggest new target structure for deep brain stimulation

Nearly ten percent of all cases of depression are so severe that the patients do not respond to any established treatment method. Targeted stimulation of areas in the brain using a type of "brain pacemaker" has recently raised hopes: According to initial studies, half of patients with the most severe depression treated in this manner see a significant improvement in mood.

31 Jan 2011

New nicotine addiction mechanism revealed

A new discovery has shown why some people cannot give up tobacco and may lead to new anti-smoking treatments. The researchers have found a brain pathway which when defective leads to an uncontrollable desire to smoke. This is a “sub-unit” of a receptor protein sensitive to nicotine.

31 Jan 2011

Neuroscience News and Research

USF Health sponsors conference on Parkinson's disease and multiple sclerosis

Coordinated behavior occurs whether or not neurons are actually connected via synapses

Concert and WRAIR enter CRADA to evaluate novel compound for seizure protection associated with TBI

HealthCore, AstraZeneca collaborate to conduct real-world studies on disease states, treatment

ImmunoCellular Therapeutics initiates enrollment in ICT-107 Phase II trial for GBM

Ritalin may help improve brain function in children with iron deficiency

International scientist team identifies gene mutation strongly linked to schizophrenia

Malarial drugs may help treat specific form of frontotemporal dementia

Older people with metabolic syndrome may face high risk of developing memory loss

New study to address causes and risk factors of ovarian cancer in African American women

FDA issues Complete Response Letter for approval of Eisai's rabeprazole sodium extended-release capsules

Defective nucleoli linked to Parkinson's disease

Drugs affecting brain noradrenaline levels could improve breathing in sleep apnea patients

Research discovers new role of TRPV1 receptors in regulation of locomotor activity

Specific brain network acts as event monitoring system

Widespread screening or ultrasound for blocked neck arteries not necessary to determine stroke risk

Walk briskly to boost memory

Brain scans can predict smokers' behavior change: New study

Physicians suggest new target structure for deep brain stimulation

New nicotine addiction mechanism revealed

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