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Researchers are in the race to beat Omicron

David Veesler and his lab members aren't getting much sleep these days. In the final weeks of 2021, he and his team worked around the clock to post four coronavirus papers on the preprint server bioRxiv.

24 Jan 2022

Gene replacement therapy could help mend a broken heart, study suggests

How can you mend a broken heart? According to researchers from Japan, in some cases gene replacement therapy just might do the trick.

24 Jan 2022

Researchers find ELF5 gene a leading candidate behind severe COVID-19

Are there any risk factors that predispose patients to severe COVID-19 outcomes? A recent study published in the medRxiv* preprint server sheds light on this popular question. Using a combination of population genetics to single-cell RNA sequencing, European researchers identified the respiratory epithelial cell-specific ELF5 gene as a potential mediator for severe COVID-19 cases.

24 Jan 2022

Study shows how SARS-CoV-2 Omicron evades our immune response and remains infective

A recent study published in the journal Science brings a detailed chemical and molecular perspective on the improved evasion of antibodies against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the retention of strong interactions with the receptor as two principal factors underneath the notorious transmissibility of the SARS-CoV-2 Omicron variant.

23 Jan 2022

An algorithm to predict host cleavage targets of SARS-CoV-2 3CLPro

In a recent study posted to the bioRxiv* preprint server, researchers developed a novel bioinformatic algorithm to predict host cleavage targets of the SARS-CoV-2 3C-like protease (3CLPro).

23 Jan 2022

Nirmatrelvir, Molnupiravir, and Remdesivir hold-up against SARS-CoV-2 Omicron variant in vitro

In a recent study posted to the bioRxiv* preprint server, researchers test three severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antivirals authorized for emergency use by the United States Food and Drug Administration (FDA) for their in vitro potency against several SARS-CoV-2 variants, including the currently dominant Omicron train.

23 Jan 2022

Genetic marker linked to higher risk of death in COVID-19 patients

A new study discusses the importance of single nucleotide polymorphisms in the Rab46 gene as a marker of adverse outcomes in high-risk COVID-19 patients.

23 Jan 2022

Novel SARS-CoV-2 mutations reported in chronic HIV patients

A new study describes the emergence of new SARS-CoV-2 variants in three immunocompromised patients.

23 Jan 2022

Robust BNT162b2 vaccine-induced B and T-cell immunity against early SARS-CoV-2 variants

Researchers describe the state of adaptive immunity following vaccination with the Pfizer-BioNTech BNT162b2 COVID-19 vaccine.

23 Jan 2022

SARS-CoV-2 Omicron associated with fewer lower and more upper respiratory tract symptoms

Researchers assess the impact of the SARS-CoV-2 Omicron variant of concern on symptoms of SARS-CoV-2 infection.

23 Jan 2022

Paxlovid provides a glimpse into the future against SARS-CoV-2

A recent study reveals that nirmatrelvir is potent and effective against the SARS-CoV-2 Omicron variant.

23 Jan 2022

Scientists develop new drug delivery system for treating genetic diseases

A team of researchers led by Harvard and Broad Institute scientists has developed a new drug delivery system using engineered DNA-free virus-like particles (eVLPs) to package and deliver therapeutic levels of gene-editing proteins to animal models of disease.

22 Jan 2022

MU researchers identify highly prevalent mutations specific to Omicron variant

While the Omicron variant continues to infect people around the world, researchers at the University of Missouri have identified the highly prevalent, specific mutations that are causing the Omicron variant's high rate of infection.

22 Jan 2022

Many care home residents, staff tested positive for Covid-19 during the first two waves of the pandemic

More than a third of care home residents and a quarter of care home staff in England showed evidence of infection with SARS-CoV-2 during the first two waves of the pandemic, according to a new study led by UCL (University College London) researchers.

22 Jan 2022

Novel compound found in mussels helps increase the durability of dental fillings

Leading researchers from the Faculty of Dentistry, the University of Hong Kong, Wuhan University, and the Peking University Shenzhen Hospital have found that a compound found in mussels helps increase the durability of a dental filling.

22 Jan 2022

Alphacoronaviruses found to be common in bats in the upper Midwestern United States

In a new study, researchers used a pan-coronavirus PCR to screen bats submitted for rabies testing owing to human exposure in order to find potentially novel bat CoVs that may represent a concern to people.

21 Jan 2022

Researchers design neural network to predict severity of COVID-19 variants

In a new study, researchers predict the risk of infection with severe coronavirus disease 2019 from the sequence of the spike protein.

21 Jan 2022

Study shows monoclonal antibody and antiviral therapy are useful in preventing the severity of SARS-CoV-2 Omicron infection

In a new study, researchers assessed the efficacy of the FDA-approved therapeutic mAbs, as well as to small-molecule antiviral agents against the SARS-CoV-2 Omicron variant in Syrian hamsters.

21 Jan 2022

Scientists identify a new switch for controlling motor proteins

Inside neurons, motor proteins haul precious cargo, moving essential goods along thread-like roadways called microtubule tracks.

21 Jan 2022

Study supports that Omicron variant has shifted to better usage of Cathepsin B/L entry pathway

A new study analyzed new data on the Omicron variant and indicated the altered cell entry pathways compared to other variants.

21 Jan 2022

Protein C News and Research

Researchers are in the race to beat Omicron

Gene replacement therapy could help mend a broken heart, study suggests

Researchers find ELF5 gene a leading candidate behind severe COVID-19

Study shows how SARS-CoV-2 Omicron evades our immune response and remains infective

An algorithm to predict host cleavage targets of SARS-CoV-2 3CLPro

Nirmatrelvir, Molnupiravir, and Remdesivir hold-up against SARS-CoV-2 Omicron variant in vitro

Genetic marker linked to higher risk of death in COVID-19 patients

Novel SARS-CoV-2 mutations reported in chronic HIV patients

Robust BNT162b2 vaccine-induced B and T-cell immunity against early SARS-CoV-2 variants

SARS-CoV-2 Omicron associated with fewer lower and more upper respiratory tract symptoms

Paxlovid provides a glimpse into the future against SARS-CoV-2

Scientists develop new drug delivery system for treating genetic diseases

MU researchers identify highly prevalent mutations specific to Omicron variant

Many care home residents, staff tested positive for Covid-19 during the first two waves of the pandemic

Novel compound found in mussels helps increase the durability of dental fillings

Alphacoronaviruses found to be common in bats in the upper Midwestern United States

Researchers design neural network to predict severity of COVID-19 variants

Study shows monoclonal antibody and antiviral therapy are useful in preventing the severity of SARS-CoV-2 Omicron infection

Scientists identify a new switch for controlling motor proteins

Study supports that Omicron variant has shifted to better usage of Cathepsin B/L entry pathway

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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