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Bat coronavirus ecology, evolution, and spillover

In a review published in Nature Reviews Microbiology, the authors collate information about the ecology and evolution of bat coronaviruses.

24 Nov 2021

SARS-CoV-2 moves between permissive cells and non-permissive neuronal cells via tunneling nanotubes (TNT)

Scientists investigate the neuroinvasive potential of SARS-CoV-2 and the role of tunneling nanotubes (TNTs) in spreading the infection to neighboring cells.

23 Nov 2021

An increase in the half-life of remdesivir for COVID-19 treatment

In this study, researchers analyzed several drug candidates to investigate their efficacy against a broad spectrum of coronaviruses in cell culture studies.

23 Nov 2021

Does SARS-CoV-2 infection contribute to adrenal gland dysfunction?

New research suggests that SARS-CoV-2 infection can directly target and cause cellular damage to the adrenal glands.

23 Nov 2021

IFITM proteins are important replication cofactors for SARS-CoV-2, including Delta variant

In a study recently published on the bioRxiv* preprint server, researchers investigated the IFITM2 dependency of SARS-CoV-2 VOCs, including the delta variant for efficient infection.

22 Nov 2021

Paper-based innovations for COVID-19 diagnosis

A review discusses paper-based devices and platforms targeting SARS-CoV-2 for low-cost PoC diagnosis and serological antibody testing.

22 Nov 2021

Impact of ultraviolet disinfection on nosocomial transmission of SARS-CoV-2 and other infectious diseases

A new review article determines the role of UV disinfection for nosocomial transmission of COVID-19 and other infectious diseases.

22 Nov 2021

Bioinformatics analysis identifies pathways involved in intestinal SARS-CoV-2 infection

Researchers recently used bioinformatics analysis techniques to explore the diseases caused by SARS-CoV-2 infection in the human digestive tract.

22 Nov 2021

Functions of glycosylation in SARS-CoV-2 proteins and human receptor ACE2

In a review published in Signal Transduction and Targeted Therapy, researchers from Sichuan University have reviewed the available literature.

19 Nov 2021

Comparing effectiveness of virus and patients-centered strategies to reduce COVID-19 mortality

Researchers from Sorbonne Université have been reviewing papers exploring different anti-COVID-19 drugs.

19 Nov 2021

Predicting the capacity of mammal species to become zoonotic SARS-CoV-2 hosts

Researchers identified a subset of species in which the threat of spillback infection appears the most significant due to location and increased contact with humans in areas with a high prevalence of SARS-CoV-2.

19 Nov 2021

Structure of SARS-CoV-2 spike protein postfusion

A new study published in PNAS proposes a higher resolution in situ structure of the SARS-CoV-2 spike protein in its postfusion state.

18 Nov 2021

The antiviral function of BET protein against SARS-CoV-2 infection

Considering the past shreds of evidence on BRD2 and BRD4 associated with viral infections, researchers have recently evaluated the function of all relevant BET proteins during COVID-19 infection.

17 Nov 2021

P681H mutation helps SARS-CoV-2 VOCs replicate faster and resist innate immunity

In the current study, researchers compare the IFITM sensitivities of major SARS-CoV-2 VOCs.

17 Nov 2021

Interactions between SARS-CoV-2 S protein and ACE2 receptor using fluorescence correlation spectroscopy

Researchers used advanced two-color fluorescence cross-correlation spectroscopy to demonstrate the interaction between human ACE2 and the S1 subunit of SARS-CoV-2 and SARS-CoV.

17 Nov 2021

What genes affect the COVID-19 gender imbalance?

Many studies have established that coronavirus disease 2019 (COVID-19) is more infective in men than women, and men are more at risk of severe disease. While some have suggested that behavioral differences could explain increased transmission to men, this does not explain the more morbid prognosis.

16 Nov 2021

ACE2 News and Research

Bat coronavirus ecology, evolution, and spillover

SARS-CoV-2 moves between permissive cells and non-permissive neuronal cells via tunneling nanotubes (TNT)

An increase in the half-life of remdesivir for COVID-19 treatment

Does SARS-CoV-2 infection contribute to adrenal gland dysfunction?

IFITM proteins are important replication cofactors for SARS-CoV-2, including Delta variant

Paper-based innovations for COVID-19 diagnosis

Impact of ultraviolet disinfection on nosocomial transmission of SARS-CoV-2 and other infectious diseases

Bioinformatics analysis identifies pathways involved in intestinal SARS-CoV-2 infection

Functions of glycosylation in SARS-CoV-2 proteins and human receptor ACE2

Comparing effectiveness of virus and patients-centered strategies to reduce COVID-19 mortality

Predicting the capacity of mammal species to become zoonotic SARS-CoV-2 hosts

Structure of SARS-CoV-2 spike protein postfusion

The antiviral function of BET protein against SARS-CoV-2 infection

P681H mutation helps SARS-CoV-2 VOCs replicate faster and resist innate immunity

Interactions between SARS-CoV-2 S protein and ACE2 receptor using fluorescence correlation spectroscopy

What genes affect the COVID-19 gender imbalance?

How effective is the COMIRNATY BNT162b2 vaccine against the SARS-CoV-2 Lambda variant?

Discovery of new receptor that interacts with SARS-CoV-2 spike, suppresses infection

SARS-CoV-2 replicates in human placenta with release of infectious viral particles

Broad neutralization capability of potent nanobody against SARS-CoV-2 variants

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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