Developmental Biology News and Research

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New research reveals how autophagy keeps neural stem cells to replace damaged brain, nerve cells

Deep inside your brain, a legion of stem cells lies ready to turn into new brain and nerve cells whenever and wherever you need them most. While they wait, they keep themselves in a state of perpetual readiness - poised to become any type of nerve cell you might need as your cells age or get damaged.

11 Apr 2013

UCSB researchers examine role played by Rhs proteins in bacterial intercellular competition

There's an epic battle taking place that's not on the national radar: intercellular competition. While it's not an Olympic event, new research from UC Santa Barbara demonstrates that this microscopic rivalry can be just as fierce as humans going for the gold.

9 Apr 2013

Researchers study influence of muscle types, body metabolism in diabetes

Researchers in the Life Sciences Institute at the University of Michigan have challenged a long-held belief that whitening of skeletal muscle in diabetes is harmful.

8 Apr 2013

Fruit fly study offers clues to wound healing

A person's skin and a fruit fly's exoskeleton, called a "cuticle" may not look alike, but both coverings protect against injury, infection, and dehydration.

6 Apr 2013

Scientists say DHA-rich fish oil enhances B cell activity

Fish oil rich in DHA and EPA is widely believed to help prevent disease by reducing inflammation, but until now, scientists were not entirely sure about its immune enhancing effects. A new report appearing in the April 2013 issue of the Journal of Leukocyte Biology, helps provide clarity on this by showing that DHA-rich fish oil enhances B cell activity, a white blood cell, challenging the notion that fish oil is only immunosuppressive.

2 Apr 2013

Research shows certain cells take on new identities through reprogramming mechanism

Researchers have been able to reprogram cells experimentally, but few have shown that cells can change their identities under normal physiological conditions in the body, particularly in mammals.

29 Mar 2013

Researchers uncover DNA rearrangement process for sex determination in Tetrahymena

It's been more than 50 years since scientists discovered that the single-celled organism Tetrahymena thermophila has seven sexes. But in all that time, they've never known how each cell's sex, or "mating type," is determined.

28 Mar 2013

Research paper highlights implementation of infectious disease curriculum in Boston Public Schools

A research paper published online this month in Academic Medicine highlights the successful development, implementation, and effects of an infectious disease curriculum that has now been piloted in five Boston Public Schools.

27 Mar 2013

Study: Neural-crest stem cells also play a key role in building olfactory sensory neurons

When our noses pick up a scent, whether the aroma of a sweet rose or the sweat of a stranger at the gym, two types of sensory neurons are at work in sensing that odor or pheromone.

26 Mar 2013

Scientists find new mechanism for guiding growth of nerves

A new mechanism for guiding the growth of nerves that involves cell-death machinery has been found by scientists at the University of Nevada, Reno that may bring advances in neurological medicine and research.

26 Mar 2013

Brown fat cells protective against obesity and diabetes

Brown fat is a hot topic, pardon the pun. Brown fats cells, as opposed to white fat cells, make heat for the body, and are thought to have evolved to help mammals cope with the cold. But, their role in generating warmth might also be applied to coping with obesity and diabetes.

15 Mar 2013

Scientists reveal genetic activity that led to development of wings in fruit flies

Scientists have delved deeper into the evolutionary history of the fruit fly than ever before to reveal the genetic activity that led to the development of wings - a key to the insect's ability to survive.

12 Mar 2013

UT Southwestern researcher to receive March of Dimes Prize in Developmental Biology

Dr. Eric Olson, chairman of molecular biology at UT Southwestern Medical Center, is the 2013 recipient of the March of Dimes Prize in Developmental Biology for identifying key genetic pathways in the formation of the heart and other muscles.

11 Mar 2013

Scientists report successful blocking of tumor development in genetic mouse model of human cancer

UT Southwestern Medical Center scientists report the first successful blocking of tumor development in a genetic mouse model of an incurable human cancer.

6 Mar 2013

Blocking aPKC activity can stop growth of transplanted skin tumors resistant to vismodegib

Hailed as a major step forward in the effort to develop targeted cancer therapies, a recently approved drug for the most common type of skin cancer has been a mixed blessing for patients. Although the initial response is usually dramatic, the tumors often recur as the cancer becomes resistant to treatment.

28 Feb 2013

Researchers discover that tympanic border cells can enable hearing

Researchers at the Stanford University School of Medicine have identified a group of progenitor cells in the inner ear that can become the sensory hair cells and adjacent supporting cells that enable hearing.

27 Feb 2013

Wnt-induced Lgr5 expression marks stem cell production in the liver

For decades scientists around the world have attempted to regenerate primary liver cells known as hepatocytes because of their numerous biomedical applications, including hepatitis research, drug metabolism and toxicity studies, as well as transplantation for cirrhosis and other chronic liver conditions. But no lab in the world has been successful in identifying and growing liver stem cells in culture -- using any available technique - until now.

26 Feb 2013

Insight into cellular operations that give extraordinary staying power to S. mansoni

From the point of view of its ultimate (human) host, the parasitic flatworm Schistosoma mansoni has a gruesome way of life. It hatches in feces-tainted water, grows into a larva in the body of a snail and then burrows through human skin to take up residence in the veins. Once there, it grows into an adult, mates and, if it's female, starts laying eggs. It can remain in the body for decades.

26 Feb 2013

HDAC-mediated mechanisms play critical role in regulating lung repair and regeneration

Lung diseases such as asthma and chronic obstructive pulmonary disease (COPD) are on the rise, according to the American Lung Association and the National Institutes of Health.

26 Feb 2013

Tranylcypromine may also hold promise in treating sickle cell disease

An antidepressant drug used since the 1960s may also hold promise for treating sickle cell disease, according to a surprising new finding made in mice and human red blood cells by a team from the University of Michigan Medical School.

19 Feb 2013

Developmental Biology News and Research

New research reveals how autophagy keeps neural stem cells to replace damaged brain, nerve cells

UCSB researchers examine role played by Rhs proteins in bacterial intercellular competition

Researchers study influence of muscle types, body metabolism in diabetes

Fruit fly study offers clues to wound healing

Scientists say DHA-rich fish oil enhances B cell activity

Research shows certain cells take on new identities through reprogramming mechanism

Researchers uncover DNA rearrangement process for sex determination in Tetrahymena

Research paper highlights implementation of infectious disease curriculum in Boston Public Schools

Study: Neural-crest stem cells also play a key role in building olfactory sensory neurons

Scientists find new mechanism for guiding growth of nerves

Brown fat cells protective against obesity and diabetes

Scientists reveal genetic activity that led to development of wings in fruit flies

UT Southwestern researcher to receive March of Dimes Prize in Developmental Biology

Scientists report successful blocking of tumor development in genetic mouse model of human cancer

Blocking aPKC activity can stop growth of transplanted skin tumors resistant to vismodegib

Researchers discover that tympanic border cells can enable hearing

Wnt-induced Lgr5 expression marks stem cell production in the liver

Insight into cellular operations that give extraordinary staying power to S. mansoni

HDAC-mediated mechanisms play critical role in regulating lung repair and regeneration

Tranylcypromine may also hold promise in treating sickle cell disease

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