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New fluorescence microscopy technique produces nanoscale 3D images of living cells

A new fluorescence microscopy technique has produced the world's first nanoscale 3D images of molecules in a whole, living cell, researchers at KTH Royal Institute of Technology reported.

12 Jan 2021

Researchers develop improved process for large-scale electron microscopy to visualize small structures

How are networks of neurons connected to make functional circuits? This has been a long-standing question in neuroscience. To answer this fundamental question, researchers from Boston Children's Hospital and Harvard Medical School developed a new way to study these circuits and in the process learn more about the connections between them.

12 Jan 2021

Researchers identify a new link between seizures and connexin 36 deficiency

For the brain to learn, retain memories, process sensory information, and coordinate body movements, its groups of nerve cells must generate coordinated electrical signals. Disorder in synchronous firing can impair these processes and, in extreme cases, lead to seizures and epilepsy.

12 Jan 2021

Researchers succeed in mapping the structure of virus that causes diarrhea

Researchers at Umeå University in Sweden have for the first time at the atomic level succeeded in mapping what a virus looks like that causes diarrhea and annually kills about 50,000 children in the world.

11 Jan 2021

MSU researchers show how microbes could soak up toxic pollutants

When Michigan State University's Gemma Reguera first proposed her new research project to the National Science Foundation, one grant reviewer responded that the idea was not "environmentally relevant."

8 Jan 2021

Researchers demonstrate lab tool that simplifies simulations of the human intestine

Rice University and Baylor College of Medicine researchers have found a way to mimic conditions in intestines, giving them a mechanical model for the real-time growth of bacterial infections.

8 Jan 2021

Researchers receive $2.95 million grant to create improved diagnostics for worm infections

Global campaigns to eliminate two tropical parasitic worm infections have been hindered by a lack of good diagnostic tools.

7 Jan 2021

Researchers receive $2.1 million NIH grant to study causes of congenital heart defects

Congenital heart defects are the most common type of birth defect, affecting nearly 1% of births in the United States each year, according to the Centers for Disease Control. Doctors have been unable to lower that number due to a lack of knowledge about their source.

5 Jan 2021

Comprehensive review details the evolution of surgical microscopes

A clear view of anatomical structures is vital for the success of surgery--especially in microsurgery where narrow anatomical cavities or proximity to vulnerable organs and tissues can pose significant risks to patient health.

5 Jan 2021

Brain damage is not caused by direct COVID-19 attack, indicates study

n an in-depth study of how COVID-19 affects a patient's brain, National Institutes of Health researchers consistently spotted hallmarks of damage caused by thinning and leaky brain blood vessels in tissue samples from patients who died shortly after contracting the disease.

3 Jan 2021

Self-learning algorithms can help analyze biological image data

Imaging techniques enable a detailed look inside an organism. But interpreting the data is time-consuming and requires a great deal of experience.

28 Dec 2020

Alterations in fetal microglia may lead to developmental and psychiatric disorders

Researchers at the Kobe University Graduate School of Medicine have revealed that alterations in fetal microglia resulting from maternal inflammation could contribute towards the onset of developmental and psychiatric disorders.

23 Dec 2020

Research shows how colanic acid extends lifespan in C. elegans

Baylor College of Medicine researcher Meng Wang had already shown that bacteria that make a metabolite called colanic acid (CA) could extend the lifespan of worms in her lab by as much as 50%, but her collaboration with Rice University synthetic biologist Jeffrey Tabor is providing tools to answer the bigger question of how the metabolite imparts longer life.

22 Dec 2020

Early clinical data demonstrates the efficacy of existing drug in treating COVID-19

In what has the potential to significantly change how Corona patients are being treated and the severity of the disease, research spearheaded at Jerusalem's Hebrew University gathered early clinical evidence demonstrating the efficacy of an existing drug in treating COVID-19.

22 Dec 2020

Anti-diarrhea drug triggers cell death in glioblastoma cells

In cell culture, loperamide, a drug commonly used against diarrhea, proves effective against glioblastoma cells. A research team at Goethe University has now unraveled the drug’s mechanisms of action of cell death induction and – in doing so – has shown how this compound could help attack brain tumors that otherwise are difficult to treat.

22 Dec 2020

Study shows how specific Salmonella bacteria evolved to cause bloodstream infection

University of Liverpool scientists have exploited the combined power of genomics and epidemiology to understand how a type of Salmonella bacteria evolved to kill hundreds of thousands of immunocompromised people in Africa.

22 Dec 2020

Researchers discover novel mechanism by which cells turn over mitochondria

Mitochondria are cellular organelles that generate most of the energy cells need to function, and thus play an important role in maintaining cell health.

21 Dec 2020

New microscope could allow surgeons to inspect tumor margins within minutes

When surgeons remove cancer, one of the first questions is, "Did they get it all?" Researchers from Rice University and the University of Texas MD Anderson Cancer Center have created a new microscope that can quickly and inexpensively image large tissue sections, potentially during surgery, to find the answer.

18 Dec 2020

Cell atlas helps better understand the biology of tropical disease parasite

The first cell atlas of an important life stage of Schistosoma mansoni, a parasitic worm that poses a risk to hundreds of millions of people each year, has been developed by researchers at the Wellcome Sanger Institute and their collaborators.

18 Dec 2020

Scientists discover how a 'sociable' protein can hold clues about Alzheimer's origin

An international team of scientists led by the ESRF, the European Synchrotron, have found how the ECSIT protein dictates the behavior of proteins linked to the energy activity in mitochondria, which is largely affected in Alzheimer's disease.

16 Dec 2020

Microscope News and Research

New fluorescence microscopy technique produces nanoscale 3D images of living cells

Researchers develop improved process for large-scale electron microscopy to visualize small structures

Researchers identify a new link between seizures and connexin 36 deficiency

Researchers succeed in mapping the structure of virus that causes diarrhea

MSU researchers show how microbes could soak up toxic pollutants

Researchers demonstrate lab tool that simplifies simulations of the human intestine

Researchers receive $2.95 million grant to create improved diagnostics for worm infections

Researchers receive $2.1 million NIH grant to study causes of congenital heart defects

Comprehensive review details the evolution of surgical microscopes

Brain damage is not caused by direct COVID-19 attack, indicates study

Self-learning algorithms can help analyze biological image data

Alterations in fetal microglia may lead to developmental and psychiatric disorders

Research shows how colanic acid extends lifespan in C. elegans

Early clinical data demonstrates the efficacy of existing drug in treating COVID-19

Anti-diarrhea drug triggers cell death in glioblastoma cells

Study shows how specific Salmonella bacteria evolved to cause bloodstream infection

Researchers discover novel mechanism by which cells turn over mitochondria

New microscope could allow surgeons to inspect tumor margins within minutes

Cell atlas helps better understand the biology of tropical disease parasite

Scientists discover how a 'sociable' protein can hold clues about Alzheimer's origin

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