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Heparinase I is not a suitable replacement for protamine

The results of an international clinical trial led by Duke University Medical Center researchers has shown that a new drug is not a suitable replacement for protamine, a drug that has been used for more than 40 years after coronary artery bypass surgery to return thinned blood to its normal state.

1 Aug 2005

Controlling the expression of genes by turning them on or off could produce a drug for the treatment or cure of almost any disease

A new technique aimed at directly controlling the expression of genes by turning them on or off at the DNA level could lead to drugs for the treatment or cure of many diseases, say researchers at UT Southwestern Medical Center.

1 Aug 2005

Pseudomonas aeruginosa has broken the immune system's code

The human opportunistic pathogen, Pseudomonas aeruginosa, has broken the immune system's code, report researchers from the University of Chicago, enabling the bacteria to recognize when its host is most vulnerable and to launch an attack before the weakened host can muster its defenses.

1 Aug 2005

Two studies reveal how plague disables immune system

Two studies by researchers at the University of Chicago show how the bacteria that cause the plague manage to outsmart the immune system and how, by slightly altering one of the microbe's tools, the researchers produced what may be the first safe and effective vaccine.

1 Aug 2005

U.S. beaches getting dirtier and some are disappearing

The National Resources Defense Council (NRDC) has said this week that more and more U.S. beaches are being closed due to contamination, partly because there is more pollution and partly because of better monitoring.

31 Jul 2005

Key step in the entry of anthrax toxin into human cells

The work, which grew out of an ongoing effort to produce a better anthrax therapeutic, shows that the protective antigen component of the bacterial toxin plays an active role in transferring the other two components of the toxin through the cell membrane.

28 Jul 2005

New findings could help scientists design more effective treatments to slow or halt the progression of HIV infection

Random fluctuations in gene expression can influence the fates of cells infected with human immunodeficiency virus (HIV) far more than previously thought, according to new research from Howard Hughes Medical Institute (HHMI) researchers at the University of California, Berkeley.

28 Jul 2005

Cause of chronic sinus infections lies in the nasal mucus

Mayo Clinic researchers have found that the cause of chronic sinus infections lies in the nasal mucus -- the snot -- not in the nasal and sinus tissue targeted by standard treatment. The findings will be published in the August issue of Journal of Allergy and Clinical Immunology and are available online.

28 Jul 2005

Twenty seven dead and 131 now sick with swine flu in China

According to Chinese state media, the number of people infected by what authorities believe is a pig-borne bacterial disease in the southwest has jumped to 131.

28 Jul 2005

Bacteria in the mouth could freshen up bad breath

Researchers in the UK say they have isolated bacteria which can grow on and destroy some of the compounds that cause bad breath, and this discovery could help develop a natural way to beat halitosis and other odours such as smelly feet.

28 Jul 2005

Mixture of 8 bacteria (VSL#3) for 6 weeks helps ulcerative colitis

A mixture of bacteria developed in part by University of Alberta researchers has been proven highly effective in treating people suffering from ulcerative colitis.

25 Jul 2005

Pneumonia - another use for statins

Patients hospitalised because of pneumonia are at less risk of dying from the disease if they have been taking the widely used cholesterol-lowering drugs 'statins' before hospital admission.

25 Jul 2005

Bacteria use host's immune response to their competitive advantage

Millions of bacteria live within the recesses of our noses and upper respiratory tracts, waiting for a chance to infiltrate and infect. But long before these bacteria break through our immune defenses, they must first compete against other bacterial species to colonize the mucus-lined surfaces of our noses.

24 Jul 2005

Role of IL-24 in regulating the immune system

Researchers at Introgen Therapeutics and their collaborators at The University of Texas M. D. Anderson Cancer Center have published new findings on the role of IL-24 in regulating the immune system in the current online issue of the Journal of Leukocyte Biology.

21 Jul 2005

Sale of abortion-pill threatened by U.S. lawmakers

The U.S. Food and Drug Administration (FDA) has issued a new warning this week regarding the abortion pill RU-486 following the deaths of five women taking it, from bacterial infections.

21 Jul 2005

Health-care officials should work collaboratively with consumer groups to develop report cards on hospital infection rates

There's a growing appetite for infection-control report cards that the public could use in selecting hospitals and that hospitals could use to lower infection rates: Thirty-nine states have introduced legislation, and six have passed laws requiring reporting of certain data. In Texas, legislators created an advisory panel in their June session to study the issue.

20 Jul 2005

Moraxella catarrhalis found to be responsible for 10 percent of exacerbations of COPD

A ubiquitous bacterial strain thought to be uninvolved in chronic obstructive pulmonary disease (COPD) in fact is responsible for 2-4 million flare-ups of the condition that occur annually in the United States, researchers from the University at Buffalo have shown.

20 Jul 2005

Antibiotics should not be prescribed to patients with the common cold

Antibiotics should not be prescribed to patients with the common cold because there is scant evidence they stop other infections, and the benefits do not outweigh the risks, according to a new systematic review of current evidence.

19 Jul 2005

New way to fight antibiotic-resistant Staphylococcus infections

Researchers at the University of California, San Diego School of Medicine and Children’s Hospital and Health Center, San Diego have discovered that "Staph" bacteria use a protective golden armor to ward off the immune system, a finding with the potential to lead to new treatments for serious infections now increasingly resistant to standard antibiotics.

19 Jul 2005

Use of antibiotics increases risk of developing antibiotic resistance

A new study has shown that a prescription of antibiotics taken within the previous two months doubles the chances of patients carrying antibiotic resistant bacteria. The same effect was not seen in patients who had had antibiotics prescribed within the previous 12 months.

19 Jul 2005