Bacterial News and Research

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Structure of key protein in innate immune response

In a report published in the Journal of Biological Chemistry, scientists in Korea announced their elucidation of three-dimensional structure of CD14 and showed how it is perfectly suited to bind to certain bacterial products.

21 Mar 2005

Drug-resistant bacteria on uncooked poultry products varies by commercial brand

The presence of drug-resistant, pathogenic bacteria on uncooked poultry products varies by commercial brand and is likely related to antibiotic use in production, according to researchers at the Johns Hopkins Bloomberg School of Public Health.

16 Mar 2005

Innovative computer modeling technique predicts how protein molecule behavior in response to environmental conditions

In a development that could have great significance for efforts to understand how the basic molecular machinery of life works, researchers at the University of Texas Medical Branch at Galveston (UTMB) have successfully applied an innovative computer modeling technique to predicting how protein molecules will behave in response to different environmental conditions.

15 Mar 2005

Researchers identify biochemical target that could lead to a new class of antibiotics to fight TB

A worldwide health problem, tuberculosis kills more people than any other bacterial infection. The World Health Organization estimates that two billion people are infected with TB, and that two million people die each year from the disease.

14 Mar 2005

Research shows how bacteria respond when subjected to environmental alterations in space stations

An article in Journal of Applied Microbiology investigates how bacteria respond when they are subjected to environmental alterations, such as those of space stations, which feature lowered effects of gravity.

14 Mar 2005

Discovery may provide a new target to treat sepsis

Part of the immune system's pro-inflammatory response to bacterial invasion is to increase nitric oxide levels with an enzyme called inducible nitric oxide synthase.

14 Mar 2005

New way of looking at MicroRNA and how it controls gene expression

A group of scientists at The Scripps Research Institute is reporting a discovery that sheds light on an area of research fundamental to everything from the normal processes that govern the everyday life of human cells to the aberrant mechanisms that underlie many diseases, including cancer and septic shock.

13 Mar 2005

Biologists discover why 10% of Europeans are safe from HIV infection

Scientists have known for some time that these individuals carry a genetic mutation (known as CCR5-Ä32) that prevents the virus from entering the cells of the immune system but have been unable to account for the high levels of the gene in Scandinavia and relatively low levels in areas bordering the Mediterranean.

9 Mar 2005

Norovirus found to cause traveler's diarrhea

A majority of traveler’s diarrhea cases among U.S. travelers to Mexico and Guatemala were attributed to Norovirus, a common cause of nonbacterial gastroenteritis outbreaks usually associated with developed countries, according to a new study by researchers at the Johns Hopkins Bloomberg School of Public Health and other institutions.

8 Mar 2005

DNA ejection from single phage particles

Studying phage, a primitive class of virus that infects bacteria by injecting its genomic DNA into host cells, researchers have gained insight into the driving force behind this poorly understood injection process, which has been proposed in the past to occur through the release of pressure accumulated within the viral particle itself.

7 Mar 2005

3 million newborn babies' lives could be saved for less than $1 per child

3 million newborn babies' lives could be saved for less than $1 per child, with interventions such as tetanus immunization during pregnancy, exclusive breastfeeding, clean delivery and antibiotics to treat illness.

4 Mar 2005

alpha-defensin-1, a protein found in immune cells, can control HIV infection

Theresa Chang and colleagues at Mount Sinai School of Medicine analyzed how alpha-defensin-1 inhibits HIV infection in white blood cells (CD4+ T cells). Defensins have been shown to have anti-HIV activity. The body attempts to protect itself from HIV infection via the innate immune system.

1 Mar 2005

Genome clues to amoebic dysentery

Each year, there are an estimated 50 million cases of amoebic dysentery, causing up to 100,000 deaths, mostly in developing countries. On Thursday 24 February 2005, researchers at the Wellcome Trust Sanger Institute and their colleagues reported in Nature magazine the genome sequence of the parasite that causes the disease, Entamoeba histolytica.

1 Mar 2005

Guidelines designed to track potentially deadly infections in hospitals and clinics

Guidelines released on Monday by the U.S. Centers for Disease Control and Prevention, are designed to help track and alert the public to potentially deadly infections in hospitals and clinics.

1 Mar 2005

New study following 12,574 individuals over the course of three years of HAART

Although clinical progression to AIDS of patients infected with Human immunodeficiency virus (HIV) has declined since the introduction of Highly Active Antiretroviral Therapy (HAART), there is little data on the changes in incidence of AIDS-defining events during the first few years of therapy.

28 Feb 2005

Scientists identify immune-system mutation

A team of Fox Chase Cancer Center scientists led by immunologist Dietmar J. Kappes, Ph.D., has identified the genetic mutation that keeps a mouse strain from developing white blood cells, or lymphocytes, called helper T cells. The report by Kappes and his colleagues appears in the Feb. 24 issue of Nature.

27 Feb 2005

Discovery could lead to the prevention, and possibly treatment of autoimmune diseases such as Type 1 diabetes

Scientists at the University of Maryland School of Medicine in Baltimore have identified a way to prevent Type I diabetes in rats that are genetically prone to develop the disease.

23 Feb 2005

MRSA superbug on the run from Sussex scientist

A groundbreaking new treatment to combat the hospital killer bug MRSA, which is estimated to cause up to 5,000 deaths a year in Britain, is being developed by a University of Sussex scientist.

23 Feb 2005

Cesarean delivery is associated with an increased risk of childhood asthma hospitalization in premature infants

Cesarean delivery is associated with an increased risk of childhood asthma hospitalization in premature infants, but not in full-term infants, according to a report published in this month’s Annals of Allergy, Asthma & Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI).

22 Feb 2005

Three-day antibiotic treatment for treating bladder infections in women

A three-day regimen of the antibiotic amoxicillin-clavulanate is not as effective as ciprofloxacin at treating an uncomplicated bladder infection in women, according to a study conducted by Thomas M. Hooton, M.D., of the University of Washington and Harborview Medical Center, Seattle, and colleagues.

21 Feb 2005