Immune Response News and Research

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Oglufanide disodium in new hepatitis C trial

Physicians at Southern Health have started a phase IIa clinical trial designed to test the efficacy of a new strategy for defeating hepatitis C viral infection, one of the toughest infectious diseases in the modern world.

26 Aug 2007

Tumors use enzyme to recruit regulatory T-cells and suppress immune response

One way tumors fly under the radar of the immune system is by using IDO, an enzyme used by fetuses to help avoid rejection, to recruit powerful regulatory T cells that turn down the immune response, researchers say.

17 Aug 2007

Researchers discover how a protein modulates the inflammatory response in acute respiratory distress syndrome

Researchers at the University of Illinois at Chicago College of Medicine have discovered how a protein modulates the inflammatory response in sudden, life-threatening lung failure.

17 Aug 2007

First biomarker discovered that predicts prostate cancer outcome

Mayo Clinic researchers have identified the first immune molecule that appears to play a role in prostate cancer development and in predicting cancer recurrence and progression after surgery.

17 Aug 2007

Baxter awarded major contract for flu vaccine in the event of a pandemic

Baxter International Inc. has announced that Baxter's European subsidiary in the United Kingdom has entered into an advanced supply agreement with the Department of Health that contains an option to purchase pandemic influenza vaccine in the event the World Health Organization (WHO) declares a pandemic.

From Baxter International Inc. 17 Aug 2007

Metabolic cell activity directly controls life and death decisions in cells

Researchers at the University of Pennsylvania School of Medicine have found that proteins known to promote cell death are also necessary for the maturation and proliferation of immune cells.

13 Aug 2007

Biomira and Merck KGaA sign agreements on Stimuvax

Biomira Inc. has announced the signing of amended and restated collaboration and supply agreements related to Stimuvax with Merck KGaA of Darmstadt, Germany.

12 Aug 2007

High-intensity focused ultrasound may alerts the immune system to cancer

An intense form of ultrasound that shakes a tumor until its cells start to leak can trigger an alarm that enlists immune defenses against the cancerous invasion, according to a study led by researchers at Duke University's Pratt School of Engineering.

8 Aug 2007

Bacteria - you can live without 'em, but it won't do you any good!

The finding challenges the conventional wisdom that even harmless bacteria – and the immune response they provoke – suck up the energy of the host organism and hasten its death.

8 Aug 2007

GlaxoSmithKline receives bulk H5N1 antigen order for the US national stockpile

GlaxoSmithKline has announced that HHS has placed another order to purchase bulk H5N1 antigen for the US national stockpile of pre-pandemic vaccines.

6 Aug 2007

HMGB1 protein shown to act as an accelerator - activating the body's defenses

Toll-like receptors are the guard dogs of the immune system, sniffing out bacteria and viruses then activating the body's immune system for an attack on these invaders.

3 Aug 2007

Phase II study of TroVax vaccine in patients with metastatic colorectal cancer

A therapeutic cancer vaccine has shown effectiveness when given alongside chemotherapy to patients with metastatic colorectal cancer in a phase II trial, according to researchers at Oxford BioMedica (UK) Ltd.

2 Aug 2007

Prototype vaccine against tuberculosis

Using a novel approach, researchers at the Albert Einstein College of Medicine of Yeshiva University have developed a prototype vaccine against tuberculosis (TB) that works better in animal models than the only TB vaccine now available.

2 Aug 2007

Study of therapeutic vaccine shows promise for metastatic colorectal cancer

1 Aug 2007

Novavax begins human clinical testing of novel pandemic flu vaccine

Novavax has announced that it has begun vaccinating healthy volunteers in the first human clinical trial of its virus-like particle ("VLP") based pandemic influenza vaccine.

1 Aug 2007

Baby boomers are starting to feel the aches, pains and weight gain of aging

Because they, like others, want to feel younger for longer, food companies and food researchers are striving to meet their needs. Increased amounts of nutritional supplements and antioxidants, including calcium, vitamin D and zinc, can slow the rate of age-related disease and increase the number of healthy years, according Jeffrey Blumberg, a nutrition scientist at Tufts University and speaker here at the Institute of Food Technologists Annual Meeting & Food Expo.

1 Aug 2007

New target for Hodgkin lymphoma

Dana-Farber Cancer Institute scientists have identified a protein that prevents the body's immune system from recognizing and attacking Hodgkin lymphoma cells.

1 Aug 2007

New TB vaccine could save over a million lives

Initial trials of a new tuberculosis (TB) vaccine mean the drug will now progress to phase II trials.

31 Jul 2007

New target for drugs to fight the HIV/AIDS virus

Researchers from Rome, Italy, describe a finding in the August 2007 print issue of The FASEB Journal that could lead to new drugs to fight the HIV/AIDS virus, as well as new vaccines to prevent infection.

27 Jul 2007

Gut bacteria boost immune response to tumors

One potent, immune-based treatment for cancer is total body irradiation (TBI). This approach first depletes the body of the population of immune cells known as lymphocytes and then involves the adoptive transfer of tumor-specific T cells to the patient.

27 Jul 2007