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Scientists have identified a novel anti-tuberculosis (TB) compound

Scientists at Johnson & Johnson Pharmaceutical Research and Development have identified a novel anti-tuberculosis (TB) compound that works better and faster than the current standard of care in mouse models of TB infection.

14 Dec 2004

Study sheds light on how bacteria persist despite antibiotics

Researchers at the Hebrew University of Jerusalem and Rockefeller University in New York have demonstrated the constant presence of antibiotic-tolerant "persistent cells" within bacteria colonies and have shown, through mathematical modeling, how these cells develop into "normal" cells following their survival of even heavy dosages of antibiotics.

13 Dec 2004

New technology will advance our understanding of role of complex sugar chains decorating the surface of cells in the body

An international consortium of scientists lead by Dr. James Paulson of The Scripps Research Institute has created a technology that will advance our understanding of the role of complex sugar chains (glycans or carbohydrates) that decorate the surface of cells in the body.

8 Dec 2004

Dane County patient dumping case unloads costs on consumers

The Wisconsin Hospital Association expressed disappointment with the Wisconsin Supreme Court’s decision yesterday that allows Dane County and other counties to impose yet another hidden tax on health care consumers.

8 Dec 2004

New research is allowing biochemists to understand a key hierarchy of protein interactions that occurs in DNA

"All cancers are marked by some form of DNA replication gone awry, so a basic understanding of DNA replication is of paramount importance to those designing cancer-fighting drugs,"

8 Dec 2004

New clues in understanding why group A streptococci (GAS) has a range of bacterial afflictions in humans

Researchers have unlocked new clues in understanding why group A streptococci (GAS) has a range of bacterial afflictions in humans. One of the keys to this species of bacteria is its production of streptokinase (SK), an enzyme that activates plasminogen, the blood clot-dissolving protein in humans.

6 Dec 2004

New research aims to reduce deaths and ease burden on hospitals

New research by scientists at Australia's Macquarie University will investigate antibiotic resistance genes in humans in an effort to combat worldwide death rates due to infectious diseases and reduce the growing burden on our health system by decreasing patients' length of stay.

6 Dec 2004

Autophagy is also cell's second line of defense against invading pathogens such as strep

Cells give up their secrets slowly. Just when you think that all major cellular systems are understood, along comes a surprise. The latest is about autophagy, a major pathway for degrading and recycling within cells.

4 Dec 2004

New and revealing portrait of Yersinia pestis emerges

Yersinia pestis, the causative agent of the “Black Death” or “Bubonic” plague, has been a scourge of human civilization. One of the most virulent bacterial pathogens known, killing nearly 90% of those infected, Y. pestis was responsible for three historic pandemics that shattered whole societies.

4 Dec 2004

People could be exposed to antibiotic-resistant bacteria from breathing air from swine feeding facilities

People could be exposed to antibiotic-resistant bacteria from breathing the air from concentrated swine feeding facilities, according to researchers at the Johns Hopkins Bloomberg School of Public Health.

4 Dec 2004

FDA approval of cream to treat bacterial vaginosis

KV Pharmaceutical Company has announced that it has received approval from the United States Food and Drug Administration (FDA) to market Clindesse (clindamycin phosphate) Vaginal Cream, 2%, a single-dose prescription cream therapy indicated to treat bacterial vaginosis ("BV").

3 Dec 2004

Oral administration of saline spray may stop spread of influenza, tuberculosis, and SARS

Some individuals exhale many more pathogen-laden droplets than others in the course of ordinary breathing, scientists have found, but oral administration of a safe saline spray every six hours might slash exhalation of germs in this group by an average 72 percent.

29 Nov 2004

Salmonella pathogen uses molecular hydrogen to grow and become virulent

New research, headed by microbiologists from the University of Georgia, show for the first time that Salmonella – a widespread and often deadly bacterial pathogen – use molecular hydrogen to grow and become virulent.

29 Nov 2004

FDA approval of Tysabri, for the treatment of multiple sclerosis

Biogen and Elan Corporation have announced that the U.S. Food and Drug Administration (FDA) has approved Tysabri (natalizumab), as treatment for relapsing forms of multiple sclerosis (MS) to reduce the frequency of clinical relapses.

24 Nov 2004

Positive results of study with human lactoferrin

Pharming Group N.V. announced today the positive results from a key study with recombinant human lactoferrin (rhLF). The Company will use these results for Generally Regarded as Safe (GRAS) registration of rhLF for nutritional applications.

24 Nov 2004

Battle of Waterloo could help doctors fight death from multiple organ failure

Waterloo’s battlefield is reigniting the debate about whether modern medicine is always good for you, according to University College London (UCL) scientists who are launching a study of why some critically ill patients recover and others die from multiple organ failure - the number one killer of patients in intensive care.

23 Nov 2004

Breakthrough HIV research wins prestigious industry award

Research that could lead to a breakthrough in the treatment of HIV has scooped a University of Manchester scientist a prestigious industry award.

From The University of Manchester 23 Nov 2004

Cells linked to asthma and eczema also help cure deadly illness in mice

Mast cells are immune cells known mostly for their unwanted effects: they cause the wheezing of asthma, the itching of eczema, the sneezing and runny nose of hay fever and, in extreme cases, the life-threatening shock of anaphylaxis.

20 Nov 2004

Research advances understanding of urinary tract infections

Anyone who has ever had a urinary tract infection knows that they can be difficult to fight.

20 Nov 2004

Low-cost antibiotic co-trimoxazole should be given to all children with HIV in developing countries

Results of a randomised trial in this week’s issue of THE LANCET highlight how the low-cost antibiotic co-trimoxazole should be given to all children with HIV in developing countries to help reduce illness and death from opportunistic infections such as pneumonia.

18 Nov 2004

Bacterial News and Research

Scientists have identified a novel anti-tuberculosis (TB) compound

Study sheds light on how bacteria persist despite antibiotics

New technology will advance our understanding of role of complex sugar chains decorating the surface of cells in the body

Dane County patient dumping case unloads costs on consumers

New research is allowing biochemists to understand a key hierarchy of protein interactions that occurs in DNA

New clues in understanding why group A streptococci (GAS) has a range of bacterial afflictions in humans

New research aims to reduce deaths and ease burden on hospitals

Autophagy is also cell's second line of defense against invading pathogens such as strep

New and revealing portrait of Yersinia pestis emerges

People could be exposed to antibiotic-resistant bacteria from breathing air from swine feeding facilities

FDA approval of cream to treat bacterial vaginosis

Oral administration of saline spray may stop spread of influenza, tuberculosis, and SARS

Salmonella pathogen uses molecular hydrogen to grow and become virulent

FDA approval of Tysabri, for the treatment of multiple sclerosis

Positive results of study with human lactoferrin

Battle of Waterloo could help doctors fight death from multiple organ failure

Breakthrough HIV research wins prestigious industry award

Cells linked to asthma and eczema also help cure deadly illness in mice

Research advances understanding of urinary tract infections

Low-cost antibiotic co-trimoxazole should be given to all children with HIV in developing countries

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