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HIV drug combo Trimethoprim-sulfamethoxazole highly effective at preventing malaria

A drug combination used to prevent pneumonia and opportunistic bacterial infection in persons with HIV/AIDS has unexpectedly been found to be highly effective at preventing malaria, according to a study published in the November 15 issue of The Journal of Infectious Diseases, now available online.

18 Oct 2005

Bayer to produce new Tuberculosis drug at low prices for poor nations

A promising new antibiotic, moxifloxacin, produced by Bayer Healthcare is about to be tested against tuberculosis, a disease that kills 5,000 people a day.

18 Oct 2005

Discovery could lead to tests for the clinic or battlefield to diagnose ailments with just a few drops of blood

A way to detect fragments of broken brain cells that leak into the bloodstream may help doctors more quickly and precisely treat people with severe head injuries or brain diseases, say researchers at the University of Florida's McKnight Brain Institute.

17 Oct 2005

Antibiotic moxifloxacin as a new treatment for tuberculosis

Moxifloxacin is currently approved in more than 100 countries, including the United States, as a treatment for bacterial respiratory infections, such as bronchitis, sinusitis and pneumonia.

17 Oct 2005

$4.4 million, 4-year grant aims to bridge gap between Western and African medicine

Described as a hotspot of botanical diversity, there are more than 20,000 indigenous plant species in South Africa. Several thousand of them are used by traditional healers every day in that country for treating a range of problems from the common cold to serious diseases such as AIDS.

17 Oct 2005

Approval sought in the U.S. for 20 minute home HIV test

Authorities in the U.S. are considering the approval of the first rapid home testing kit for HIV.

17 Oct 2005

Endocytosis of HIV-1 activates plasmacytoid dendritic cells via toll-like receptor -viral RNA interactions

Progressive disease after HIV infection is inversely correlated with the presence of plasmacytoid dendritic cells (pDCs), a subset of the dendritic cell family and the major producers of type 1 interferon in the body. High numbers of pDCs is related to successful control of HIV.

13 Oct 2005

No shred of evidence that HIV-positive men who lose fat in their legs reciprocally gain fat in their bellies

There is no syndrome that causes increased belly fat and decreased facial and limb fat among HIV-positive men who take antiretroviral drugs, according to a study by researchers at the San Francisco VA Medical Center and the University of California, San Francisco.

13 Oct 2005

Why the human immune system does not function well in the weightlessness of space

Researchers at the San Francisco VA Medical Center have identified a set of key immune-response genes that do not turn on in a weightless environment. The discovery is another clue in the effort to solve an almost 40-year-old mystery

12 Oct 2005

Fijiian seaweed shows potential to kill cancer cells, bacteria and the HIV virus

Researchers have discovered 10 new molecular structures with pharmaceutical potential in a species of red seaweed that lives in the shallow coral reef along the coastline of Fiji in the south Pacific Ocean.

12 Oct 2005

Tropical diseases such as sleeping sickness, schistosomiasis, river blindness, hookworm, elephantiasis, and blinding trachoma are being ignored

"The big three" infections AIDS, TB and malaria have caught the world's attention but other disabling and fatal infectious diseases in Africa are being ignored, say three eminent tropical disease researchers in the international health journal PLoS Medicine.

11 Oct 2005

Experimental HIV vaccine progresses in trials

A novel vaccine targeted to multiple HIV subtypes found worldwide has moved into the second phase of clinical testing, the National Institute of Allergy and Infectious Diseases (NIAID) announced today.

11 Oct 2005

New way to measure the impact of AIDS on the living brain

A new University of California - Los Angeles/University of Pittsburgh imaging study for the first time shows the selective pattern of destruction inflicted by AIDS on brain regions that control motor, language and sensory functions. High-resolution 3-D color scans created from magnetic resonance images (MRI) vividly illustrate the damage.

10 Oct 2005

New report identifies over 40 infectious agents that pose significant human health problems in the United States or abroad

Vaccines have helped eradicate and tame some of history's worst infectious diseases, but there are many more diseases out there that vaccines can help overcome. The challenges society needs to confront to unlock the future promise of vaccines against the plagues of the 21st century are the focus of a new report by the American Academy of Microbiology.

9 Oct 2005

Community-level intervention program successfully delayed sexual debut and increased the use of condoms

A community-level intervention program aimed at young adolescents delays early intercourse, increases condom use and reduces the type of risky sexual behavior that can result in sexually transmitted diseases and HIV/AIDS, a Yale researcher reports in AIDS.

4 Oct 2005

Body's own defenses may cause HIV-related dementia

Publishing in the Sept. 2005 issue of the Journal of Virology, the researchers show that HIV in the temporal lobe mutates at a rate 100 times faster than in other parts of the body, triggering white blood cells to continually swarm to attack the infection. The associated overcrowding and inflammation appear to cause the dementia.

3 Oct 2005

Compounds secreted by frog skin are potent blockers of HIV infection

The findings could lead to topical treatments for preventing HIV transmission, and they reinforce the value of preserving the Earth's biodiversity.

3 Oct 2005

Training for health workers improves the quality of tuberculosis care and control without requiring extra staff

Tuberculosis is a growing problem in lower and middle income countries, including South Africa. The World Health Organization estimates that about two thirds of people with tuberculosis are never diagnosed and so cannot benefit from treatment, leaving the epidemic unchecked despite global treatment programmes.

3 Oct 2005

Risk of acquiring HIV rises during pregnancy

The risk of acquiring HIV rises during pregnancy, according to a study of women in Uganda's Rakai District led by researchers at the Johns Hopkins Bloomberg School of Public Health. The increased risk for acquiring HIV remained even after researchers controlled for behavior and other factors that contribute to HIV risk.

3 Oct 2005

Clinical trials of daily oral antiretroviral dosing as pre-exposure prophylaxis

Writing in the journal Science, an international team of researchers, clinicians and others explains that a promising, relatively new approach is for people not infected but at high risk to take drugs that might prevent them from contracting HIV. But debate over the particulars of the strategy has slowed progress.

3 Oct 2005

HIV 1 News and Research

HIV drug combo Trimethoprim-sulfamethoxazole highly effective at preventing malaria

Bayer to produce new Tuberculosis drug at low prices for poor nations

Discovery could lead to tests for the clinic or battlefield to diagnose ailments with just a few drops of blood

Antibiotic moxifloxacin as a new treatment for tuberculosis

$4.4 million, 4-year grant aims to bridge gap between Western and African medicine

Approval sought in the U.S. for 20 minute home HIV test

Endocytosis of HIV-1 activates plasmacytoid dendritic cells via toll-like receptor -viral RNA interactions

No shred of evidence that HIV-positive men who lose fat in their legs reciprocally gain fat in their bellies

Why the human immune system does not function well in the weightlessness of space

Fijiian seaweed shows potential to kill cancer cells, bacteria and the HIV virus

Tropical diseases such as sleeping sickness, schistosomiasis, river blindness, hookworm, elephantiasis, and blinding trachoma are being ignored

Experimental HIV vaccine progresses in trials

New way to measure the impact of AIDS on the living brain

New report identifies over 40 infectious agents that pose significant human health problems in the United States or abroad

Community-level intervention program successfully delayed sexual debut and increased the use of condoms

Body's own defenses may cause HIV-related dementia

Compounds secreted by frog skin are potent blockers of HIV infection

Training for health workers improves the quality of tuberculosis care and control without requiring extra staff

Risk of acquiring HIV rises during pregnancy

Clinical trials of daily oral antiretroviral dosing as pre-exposure prophylaxis

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