B Cell News and Research

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New research lays the foundation for more effectively treating pediatric brain tumor

In a ground-breaking new study, scientists have uncovered the mechanics of the blood-tumor barrier, one of the most significant obstacles to improving treatment efficacy and preventing the return of cancerous cells.

1 Nov 2022

UT Southwestern study uncovers a causative signaling pathway in breast cancer

UT Southwestern researchers have identified a causative signaling pathway in breast cancer, providing potential new targets for treatment of the most common type of cancer in women.

1 Nov 2022

First preclinical model to study the pathobiology of appendiceal cancer

Appendiceal cancer (malignancies of the appendix, a small tissue pouch that is part of the gastrointestinal tract) is very rare, occurring in perhaps one or two people per 1 million per year.

1 Nov 2022

Pitt researchers receive $792,000 to understand the biology behind ovarian cancer metastasis

Most women diagnosed with metastatic ovarian cancer have a less than five year survival rate. Researchers at the University of Pittsburgh Swanson School of Engineering are working to change that.

1 Nov 2022

Study provides insight into how sleep and wakefulness regulate inhibitory synapses

Using a mouse model, researchers have discovered a new daily rhythm in a type of synapse that dampens brain activity.

1 Nov 2022

New red blood cell destruction model based on dissipative particle dynamics within a high shear flow

Many medical devices for treating heart failure generate nonphysiological shear flow. This can trigger the destruction of red blood cells after implantation of ventricular assist devices (VADs), artificial heart valves, vascular stents, or interventional thrombectomy devices.

1 Nov 2022

Progress and challenges in the development of mRNA vaccines against respiratory syncytial virus

New research discussed the structure and life cycle of respiratory syncytial virus (RSV), the current research on the treatment and prevention of RSV infections, and the advancements in RSV mRNA vaccine technology after the surge in vaccine research during the COVID-19 pandemic.

1 Nov 2022

Protein kinase CK2 controls CD8+ T cell effector and memory functions during Listeria infection

The protein kinase CK2 is involved in a wide range of biological processes and cellular functions, including inflammatory responses and pathologies associated with inflammation.

1 Nov 2022

Single-nucleus RNA sequencing and spatial transcriptome atlas of COVID-19 livers

Researchers performed single-nucleus RNA sequencing (snRNA-seq) and spatial transcriptomic profiling of livers from deceased coronavirus disease 2019 (COVID-19) patients.

1 Nov 2022

Researchers find the root of immunosuppression and chemoresistance in TNBC tumors

Triple-negative breast cancer (TNBC) tumors gain immunosuppression and chemoresistance through interactions between interleukin 34 and myeloid-derived suppressor cells, researchers find.

1 Nov 2022

Hybrid virus particles formed from coinfections exhibit immune evasion and expanded tropism

Researchers examined virus-virus interactions using human lung cells coinfected with two co-circulating respiratory infection-causing viruses, respiratory syncytial virus (RSV) and influenza A virus (IAV).

1 Nov 2022

How does the ISG15/ISGylation system modulate Vaccinia virus infection?

Researchers demonstrated how interferon-stimulated gene 15 (ISG15) is involved in the Vaccinia virus (VACV) dissemination.

1 Nov 2022

Researchers fabricate cerebral cortical tissues in 3D and functionally integrate them into a brain lesion in mice

Researchers fabricated cerebral cortical tissues in 3D and functionally integrated them into a brain lesion in mice.

1 Nov 2022

What makes some humans mosquito magnets?

Researchers explored the reasons for the greater attractiveness of some individuals to mosquitoes.

1 Nov 2022

Novel computational method maps the architecture of human tissues in unprecedented detail

Weill Cornell Medicine researchers have developed a computational method to map the architecture of human tissues in unprecedented detail. Their approach promises to accelerate studies on organ-scale cellular interactions and could enable powerful new diagnostic strategies for a wide range of diseases.

1 Nov 2022

Researchers take a cue from viruses to make glioblastoma more vulnerable to treatment

In the tough war against glioblastoma, scientists are taking a cue from viruses on how to make the aggressive cancer more vulnerable to treatment.

1 Nov 2022

New nanovaccine greatly improves cytokine production

Cancer immunotherapies, such as immune checkpoint inhibition therapy, have been attracting attention in recent years as new methods for treating cancer. However, immune checkpoint inhibition therapy is only effective in 20%–30% of cancer patients, so developing better drug delivery systems to induce anticancer cellular immunity is necessary.

1 Nov 2022

B Cell News and Research

New research lays the foundation for more effectively treating pediatric brain tumor

UT Southwestern study uncovers a causative signaling pathway in breast cancer

First preclinical model to study the pathobiology of appendiceal cancer

Pitt researchers receive $792,000 to understand the biology behind ovarian cancer metastasis

Study provides insight into how sleep and wakefulness regulate inhibitory synapses

New red blood cell destruction model based on dissipative particle dynamics within a high shear flow

Progress and challenges in the development of mRNA vaccines against respiratory syncytial virus

Protein kinase CK2 controls CD8+ T cell effector and memory functions during Listeria infection

Single-nucleus RNA sequencing and spatial transcriptome atlas of COVID-19 livers

Researchers find the root of immunosuppression and chemoresistance in TNBC tumors

Hybrid virus particles formed from coinfections exhibit immune evasion and expanded tropism

How does the ISG15/ISGylation system modulate Vaccinia virus infection?

Researchers fabricate cerebral cortical tissues in 3D and functionally integrate them into a brain lesion in mice

What makes some humans mosquito magnets?

Novel computational method maps the architecture of human tissues in unprecedented detail

Researchers take a cue from viruses to make glioblastoma more vulnerable to treatment

New nanovaccine greatly improves cytokine production

New system to detect cancer-related markers on CTCs

Artificial intelligence-based method may help predict early-stage melanoma recurrence

New way of reprogramming immune cells shown to work in melanoma

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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