Genes News and Research

RSS

Researchers identify genetic variants related to starting point of Parkinson's disease

Researchers from the Institute of Neurosciences of the University of Barcelona, Hospital Clínic and the August Pi i Sunyer Biomedical Research Institute have identified a group of genetic variants related to the starting point of Parkinson's disease.

27 Sep 2019

Scientists use ultrasound to detect active genes in live cells

A startling new study shows that ultrasound can help scientists to understand whether specific genes are in the active or inactive state in live cells.

27 Sep 2019

Biological clock responds positively to stress

In a recent study, researchers found that the integrated stress response (ISR) is essential to stimulate the circadian clock.

27 Sep 2019

Study may help scientists to learn more about the causes of chronic pain

Researchers from North Carolina State University have found that inflammation increases neuronal activity, gene expression and sensory nerve (neurite) outgrowth in neurons involved in thermal - but not physical- sensations in mice.

27 Sep 2019

New study on gene modulation may help prevent blindness

Genes borrowed from a spider turned Peter Parker into Spiderman. If scientists can use archaea--tiny organisms similar to bacteria--as a source of useful genes for humans, might it help prevent blindness one day?

27 Sep 2019

DNA sequencing helps confirm breast cancer link between Leicester sisters

Two Leicester sisters who had their entire genomes sequenced in the hope of finding answers to their family history of breast cancer have learnt they both carry a genetic variant that significantly increases their risk of developing the disease.

27 Sep 2019

Children's of Alabama using cold sore virus to fight pediatric brain cancer

Children's of Alabama is home to one of the most exciting studies underway in pediatric cancer: evaluating the use of a cold sore virus to treat children with progressive malignant brain tumors.

26 Sep 2019

Metabolite may predict cancer versus autism risk in PTEN patients

In a new study published in American Journal of Human Genetics, a team of researchers led by Charis Eng, M.D., Ph.D., Chair of Cleveland Clinic's Genomic Medicine Institute, identified a metabolite that may predict whether individuals with PTEN mutations will develop cancer or autism spectrum disorder.

26 Sep 2019

Temporal fluctuations in protein concentrations can determine fate of stem cells

How do temporal variations in protein concentrations affect biology? It's a question that biologists have only recently begun to address, and the findings are increasingly showing that random temporal changes in the amount of certain proteins play a direct and significant role on biological processes.

26 Sep 2019

Johns Hopkins researchers identify new way to lower blood pressure in obese patients

There's no question that as body weight increases, so too does blood pressure. Now, in a study of mice, Johns Hopkins researchers have revealed exactly which molecules are likely responsible for the link between obesity and blood pressure.

From Johns Hopkins Medicine 26 Sep 2019

Study identifies 44 genes linked to age-related hearing loss

A new study published today in The American Journal of Human Genetics has identified 44 genes linked to age-related hearing loss giving a much clearer understanding of how the condition develops and potential treatments.

26 Sep 2019

AI technique helps detect people at risk of heart failure

Researchers have recently used an artificial intelligence (AL) technique to examine how MRI scans can validate how hereditary factors can impact heart function.

26 Sep 2019

New technique can rapidly image synaptic proteins at high resolution

Our brains contain millions of synapses -- the connections that transmit messages from neuron to neuron. Within these synapses are hundreds of different proteins, and dysfunction of these proteins can lead to conditions such as schizophrenia and autism.

26 Sep 2019

Study may lead to earlier detection of heart failure and new targeted treatments

Genetic research led by Queen Mary University of London could open the way to earlier identification of people at risk of heart failure and to the development of new treatments.

26 Sep 2019

Pesticide exposure on the job related to more strokes, heart attacks

A new study published in the Journal of the American Heart Association, September 25, 2019, reports that the risk of cardiovascular disease (CVD) is increased by 42% in Japanese-American men exposed to high levels of pesticide. This is the first time this outcome has been explored in this group, and indicates that the role played by occupational pesticide exposure in the pathogenesis of CVD needs to be examined.

25 Sep 2019

Dormant HIV reservoirs could be killed with RNA switch

Researchers from the University of California San Diego School of Medicine have found cellular triggers within the immune cells that could be controlled in order to kill dormant HIV-1 reservoirs in individuals with HIV-1.

25 Sep 2019

Reactivating ‘tumor suppressor’ genes could offer new therapeutic approach for cancer

Scientists have developed a method which is able to switch ‘tumor suppressor’ genes back on after they have been silenced by cancer cells.

25 Sep 2019

Study: Whole genome sequencing can improve surveillance, control of gastroenteritis

A new study into one of the UK's leading causes of gastroenteritis has shown how whole genome sequencing can improve its surveillance and control of the disease.

25 Sep 2019

Improved mapping of genomes from 1,000 Swedish individuals

In so-called whole genome sequencing, surveys are made of the total genome of an individual. It is still relatively rare in healthcare today, but it occurs at an increasing rate, for example in order to make an accurate diagnosis in the case of a rare disease.

25 Sep 2019

Molecular changes are linked with adverse events following treatment of lymphatic filariasis

The Global Program to Eliminate Lymphatic Filariasis delivers mass drug administration to 500 million people each year, and adverse events are common following treatment. Now, researchers have reported in PLOS Neglected Tropical Diseases that certain changes in gene expression are associated with these adverse events.

From PLOS ONE 25 Sep 2019