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Multiplication of ecDNA genes present in many cancer types, drives poor patients outcomes

The multiplication of genes located in extrachromosomal DNA that have the potential to cause cancer drives poor patient outcomes across many cancer types, according to a Nature Genetics study published Aug. 17, 2020 by a team of researchers including Professors Vineet Bafna and Dr.Paul Mischel of the University of California San Diego and Professor Roel Verhaak of Jackson Laboratories.

17 Aug 2020

Cashew shell compound may help repair damaged nerves

In laboratory experiments, a chemical compound found in the shell of the cashew nut promotes the repair of myelin, a team from Vanderbilt University Medical Center reports today in the Proceedings of the National Academy of Sciences.

17 Aug 2020

Paired associative stimulation promotes walking rehabilitation in paraplegic patient

The simultaneous stimulation of the motor nerves of the brain and limbs (paired associative stimulation) has yielded promising research results.

17 Aug 2020

Study reveals bacteria's secret weapon to evade immune responses

Monash Biomedicine Discovery Institute scientists have discovered a previously unknown method used by bacteria to evade immune responses.

17 Aug 2020

Study opens new therapeutic avenue for treating glioblastoma tumors

New insight into a gene that controls energy production in cancer stem cells could help in the search for a more effective treatment for glioblastoma.

17 Aug 2020

New research offers hope for treating Parkinson's disease

The American Academy of Neurology (AAN) has published, on August 12, the results of a research project conducted jointly by Cardiocentro Ticino and the EOC Neurocentro, which delivers a message of hope in the fight against Parkinson's disease, as well as providing encouraging news for the USI Faculty of Biomedical Sciences.

17 Aug 2020

New test provides information on immune response to Sars-Cov-2 in transplant patients

Even patients with suppressed immune systems can achieve a strong immune response to Sars-Cov-2. A test helps to adapt therapy following an infection.

17 Aug 2020

New clinical practice guidelines on optimal management of patients with COPD

A subcommittee of the American Thoracic Society Assembly in Sleep and Respiratory Neurobiology has released new clinical practice guidelinesto help advise clinicians on the optimal management of patients with chronic obstructive pulmonary disease (COPD) and chronic hypercapnia. Hypercapnia is the buildup of carbon dioxide in the bloodstream.

17 Aug 2020

Study demonstrates new stimulation therapy for motor rehabilitation in spinal cord injuries

The simultaneous stimulation of the motor nerves of the brain and limbs (paired associative stimulation) has yielded promising research results. Research conducted at the BioMag Laboratory, operated by the University of Helsinki, Helsinki University Hospital and Aalto University, has previously demonstrated that simultaneous transcranial magnetic stimulation of the brain and electrical stimulation of the limb nerves constitute a useful method of motor rehabilitation in patients suffering from spinal cord injuries.

17 Aug 2020

PARP inhibitor can successfully treat a subset of advanced prostate cancer patients

Results from an international clinical trial found that men with advanced prostate cancer who have mutated BRCA1/BRCA2 genes can be treated successfully with a targeted therapy known as rucaparib, resulting in recent FDA approval.

15 Aug 2020

Frequently used serology test may not detect SARS-CoV-2 antibodies, shows study

Two different types of detectable antibody responses in SARS-CoV-2 (COVID-19) tell very different stories and may indicate ways to enhance public health efforts against the disease, according to researchers at The University of Texas MD Anderson Cancer Center.

15 Aug 2020

Nanoparticle carriers expand the effectiveness of gene therapies for human eye diseases

NIBIB-funded researchers have created nanoparticles for successful gene therapy of a mouse model of macular degeneration.

15 Aug 2020

Scientists hope to find clues about how life emerged by tinkering with its oldest components

"I'm fascinated with life, and that's why I want to break it."

15 Aug 2020

Gene variants help explain link between skin condition and food allergies

Two common variants in the KIF3A gene increase the risk of young children having a dysfunctional skin barrier and developing the skin condition atopic dermatitis.

14 Aug 2020

Portable testing laboratory screens millions of bacteria in water samples

A suitcase-size portable testing laboratory could cut back the time and money spent on monitoring water quality in developing countries.

14 Aug 2020

Experimental COVID-19 vaccine prevents severe disease in mice

Now, a novel experimental vaccine that is made from a mild virus genetically-modified to carry an essential gene from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes the coronary disease (COVID-19), has shown promise in preventing pneumonia in mice infected with the virus.

14 Aug 2020

Study finds increase in support for telehealth and mobile health monitoring since COVID

Support for telehealth and mobile health monitoring has risen among healthcare workers and consumers since the rise of the COVID-19 pandemic, according to a new study.

13 Aug 2020

Natural controllers shed light on immunity mechanisms against hepatitis B

Infections in humans caused by the hepatitis B virus (HBV) represent a major public health problem. Despite the availability of effective protective vaccines, more than 250 million individuals worldwide are chronically infected according to WHO estimates.

13 Aug 2020

Genomic analysis finds link between antibiotic resistance and heavy metal contamination

Antibiotic resistance is an increasing health problem, but new research suggests it is not only caused by the overuse of antibiotics. It's also caused by pollution.

13 Aug 2020

Synthetic nanobodies prevent SARS-CoV-2 infection

A team of researchers from the University of California San Francisco has created a powerful nasal spray or inhaler that can provide high-grade protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The report is presently available on the bioRvix* preprint server.

13 Aug 2020

Laboratory News and Research

Multiplication of ecDNA genes present in many cancer types, drives poor patients outcomes

Cashew shell compound may help repair damaged nerves

Paired associative stimulation promotes walking rehabilitation in paraplegic patient

Study reveals bacteria's secret weapon to evade immune responses

Study opens new therapeutic avenue for treating glioblastoma tumors

New research offers hope for treating Parkinson's disease

New test provides information on immune response to Sars-Cov-2 in transplant patients

New clinical practice guidelines on optimal management of patients with COPD

Study demonstrates new stimulation therapy for motor rehabilitation in spinal cord injuries

PARP inhibitor can successfully treat a subset of advanced prostate cancer patients

Frequently used serology test may not detect SARS-CoV-2 antibodies, shows study

Nanoparticle carriers expand the effectiveness of gene therapies for human eye diseases

Scientists hope to find clues about how life emerged by tinkering with its oldest components

Gene variants help explain link between skin condition and food allergies

Portable testing laboratory screens millions of bacteria in water samples

Experimental COVID-19 vaccine prevents severe disease in mice

Study finds increase in support for telehealth and mobile health monitoring since COVID

Natural controllers shed light on immunity mechanisms against hepatitis B

Genomic analysis finds link between antibiotic resistance and heavy metal contamination

Synthetic nanobodies prevent SARS-CoV-2 infection

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