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Rutgers study examines link between COVID-19 and memory loss, dementia

A new Rutgers study will examine how COVID-19 is affecting individuals in a number of cognitive-related areas, including memory loss, "brain fog," and dementia.

13 Sep 2021

MD Anderson and SNIPR BIOME join forces to advance new CRISPR-based microbiome therapeutics

The University of Texas MD Anderson Cancer Center and SNIPR BIOME today announced a strategic collaboration to advance new CRISPR-based microbiome therapeutics to reduce immune-related adverse events (irAE) in patients being treated with combined immune checkpoint inhibitors.

13 Sep 2021

Newly developed antibody may be used to treat muscular dystrophy

Northwestern Medicine scientists have developed an antibody that they believe can be used to treat muscular dystrophy, findings that were published in Science Translational Medicine.

13 Sep 2021

Discovery of diverse sarbecovirus broadly neutralizing antibodies from SARS-CoV-2 “infected-vaccinated” humans

Scientists were inspired by the robust serum nAb responses in people who recovered from natural SARS-CoV-2 infection and were later vaccinated using mRNA vaccine. They isolated and characterized bnAbs from two COVID-19 convalescent donors who were recently vaccinated. These isolated bnAbs were found to be highly potent against sarbecoviruses. This research is available on the bioRxiv* preprint server.

13 Sep 2021

Results from Phase 0/1 trial of ribociclib plus everolimus in patients with high-grade glioma announced

The Ivy Brain Tumor Center at Barrow Neurological Institute, the largest early-phase drug development program for brain cancer in the world, announced results from their Phase 0/1 clinical trial of ribociclib plus everolimus in patients with high-grade glioma (HGG).

13 Sep 2021

Electroconvulsive therapy reduces deaths by suicide among depressed elders

Electroconvulsive therapy reduces deaths by suicide among older adults with depression in the months immediately following hospitalization, researchers report in the 10 September issue of the American Journal of Psychiatry.

12 Sep 2021

Neoadjuvant CPA followed by surgical resection and maintenance atezolizumab meets safety criteria

Neoadjuvant cisplatin and pemetrexed plus atezolizumab followed by surgical resection and maintenance atezolizumab met safety criteria, according to research presented today in OA13: Topics in Pleural Mesothelioma at the IASLC 2021 World Conference on Lung Cancer.

12 Sep 2021

Study finds significant variability in treatment access for patients with malignant pleural mesothelioma

A study of 2,804 patients with stage I to stage III malignant pleural mesothelioma (MPM) found significant variability in access to care and a positive association between multimodality treatment, income levels, and survival outcomes.

12 Sep 2021

Study shows how oncology practices changed after durvalumab approval for unresectable stage III NSCLC patients

A study presented today at the IASLC 2021 World Conference on Lung Cancer suggests how oncology practices in the United States changed after 2018, when durvalumab became available for patients with unresectable Stage III non-small cell lung cancer.

12 Sep 2021

High-dose chemotherapy followed by immunotherapy benefits patients with acute myeloid leukemia

A clinical trial conducted at UNC Lineberger Comprehensive Cancer Center and Johns Hopkins Sidney Kimmel Comprehensive Cancer Center found that high-dose cytarabine followed by subsequent immunotherapy treatment with pembrolizumab benefited patients with resistant or relapsed acute myeloid leukemia (AML), a highly aggressive cancer.

12 Sep 2021

First rat model recapitulates all disabling alterations experienced by patients with Morquio A disease

A research team from the Universitat Autònoma de Barcelona has generated the first rat model recapitulating all disabling alterations experienced by patients with Mucopolysaccharidosis type IVA, also known as Morquio A disease.

12 Sep 2021

Drugs that mimic effects of cigarette smoke could become a potential tool to fight COVID-19

Researchers have identified two drugs that mimic the effect of chemicals in cigarette smoke to bind to a receptor in mammalian cells that inhibits production of ACE2 proteins, a process that appears to reduce the ability of the SARS-CoV-2 virus to enter the cell.

12 Sep 2021

Tumor-related risk factors affect conversion of active surveillance to treatment for prostate cancer

For men with "low-risk" prostate cancer initially managed with active surveillance, cancer-related factors such as tumor grade and size are key risk factors for conversion to active treatment, reports a study in The Journal of Urology®, an Official Journal of the American Urological Association.

10 Sep 2021

ECMO life support is a last resort for covid, and in short supply in South

Hospital discharge day for Phoua Yang was more like a pep rally. On her way rolling out of TriStar Centennial Medical Center in Nashville, Tennessee, she teared up as streamers and confetti rained down on her. Nurses chanted her name as they wheeled her out of the hospital for the first time since she arrived in February with covid-19, barely able to breathe.

10 Sep 2021

Nanoparticles-assisted delivery of antiviral-siRNA for treatment of COVID-19

A review aimed to determine the potential of siRNA as a potential COVID-19 treatment by reviewing the currently available literature.

10 Sep 2021

Cryopreservation Excipient for Cell Therapies

AMSBIO has launched STEM-CELLBANKER® EX - a next generation cryopreservation product that eliminates the need for the traditional washing steps required in cell therapy product development.

From AMS Biotechnology 10 Sep 2021

New gene-delivering workhorse could make gene therapy safer, more effective for muscle diseases

Genetic muscle diseases lead to progressive muscle wasting and often early death, with few treatment options and no cure.

9 Sep 2021

Physical exercise can improve cancer-induced anemia

Many cancer patients suffer from anemia leaving them fatigued, weak, and an impaired ability to perform physical activity.

9 Sep 2021

Early androgens related to childhood gender nonconformity in boys

In laboratory animals, sex differences in behavior occur because different hormone levels produced by males and females influence patterns of gene expression in the developing brain.

9 Sep 2021

'Cold' tumors can be turned 'hot' with extremely low doses of radiation, study shows

A Ludwig Cancer Research study conducted in both mice and a small group of patients with advanced cancers has shown that so-called “cold” tumors that are nearly devoid of immune cells—and therefore unresponsive to immunotherapy—can be turned “hot” with extremely low doses of radiation and the rational use of existing therapies.

9 Sep 2021

Therapy News and Research

Rutgers study examines link between COVID-19 and memory loss, dementia

MD Anderson and SNIPR BIOME join forces to advance new CRISPR-based microbiome therapeutics

Newly developed antibody may be used to treat muscular dystrophy

Discovery of diverse sarbecovirus broadly neutralizing antibodies from SARS-CoV-2 “infected-vaccinated” humans

Results from Phase 0/1 trial of ribociclib plus everolimus in patients with high-grade glioma announced

Electroconvulsive therapy reduces deaths by suicide among depressed elders

Neoadjuvant CPA followed by surgical resection and maintenance atezolizumab meets safety criteria

Study finds significant variability in treatment access for patients with malignant pleural mesothelioma

Study shows how oncology practices changed after durvalumab approval for unresectable stage III NSCLC patients

High-dose chemotherapy followed by immunotherapy benefits patients with acute myeloid leukemia

First rat model recapitulates all disabling alterations experienced by patients with Morquio A disease

Drugs that mimic effects of cigarette smoke could become a potential tool to fight COVID-19

Tumor-related risk factors affect conversion of active surveillance to treatment for prostate cancer

ECMO life support is a last resort for covid, and in short supply in South

Nanoparticles-assisted delivery of antiviral-siRNA for treatment of COVID-19

Cryopreservation Excipient for Cell Therapies

New gene-delivering workhorse could make gene therapy safer, more effective for muscle diseases

Physical exercise can improve cancer-induced anemia

Early androgens related to childhood gender nonconformity in boys

'Cold' tumors can be turned 'hot' with extremely low doses of radiation, study shows

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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