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New study gives hope for potentially developing a cure for HIV

HIV latency is considered one of the biggest challenges to developing a cure for the virus.

23 Jan 2020

Scientists reverse HIV latency, take major scientific step toward curative therapies

Approximately 38 million people are infected with HIV worldwide, about 1.1 million people in the United States. Currently, people with HIV take antiretroviral therapy (ART), which can suppress HIV to undetectable levels in blood, but the virus persists throughout the body in latently infected resting CD4+ T cells.

22 Jan 2020

Smoking dormant HIV virus out into the open to develop a cure

Ever since antiretroviral treatments against HIV infection were introduced in 1996, scientists have eagerly been hunting for a cure for the disease.

9 Jan 2020

Immune cells could help kill cancer cells, finds study

Researchers from UCL Cancer Institute have found that a subset of immune cells can kill cancer cells when activated.

8 Jan 2020

Immune cell discovery could hold the key to effective therapies against cancer

Scientists at UCL have identified how a subset of immune cells are activated to kill cancerous cells, a finding in mice which could hold the key to new powerful therapies against cancer.

7 Jan 2020

ART may not be completely effective in restoring immune protection, study suggests

A study led by researchers from SUNY Downstate Health Sciences University and Oregon Health & Science University, published in the Journal of Infectious Diseases, showed that, despite successful antiretroviral therapy, antigen specific memory to vaccinations that occurred before HIV infection did not recover, even after immune reconstitution.

6 Jan 2020

CD4 T cells are not to be blamed for pushing dengue fever from bad to worse

No one knows what makes a mild dengue viral infection morph into a severe and sometimes deadly dengue hemorrhagic fever/dengue shock syndrome.

26 Dec 2019

New mechanism that impairs Treg differentiation and stability in type 1 diabetes discovered

Regulatory T cells (Tregs) prevent excessive immune reactions in healthy people. In the development of autoimmune type 1 diabetes, this protection is not sufficiently effective.

19 Dec 2019

Study finds new drivers of destructive inflammation

Scientists describe in Nature Immunology an entirely new molecular process in mice that triggers T cell-driven inflammation and causes different auto-immune diseases.

17 Dec 2019

The sympathetic nervous system can modulate action of defense cells in autoimmune disease

The results of a study conducted in Brazil suggest that the sympathetic nervous system - the part of the autonomous nervous system that controls responses to danger or stress - can modulate the action of defense cells in patients with autoimmune diseases.

16 Dec 2019

Novel HIV vaccine shows promise

There are millions living with HIV and researchers have been working towards making a successful vaccine against the deadly infection for the past 35 years with no success. Now a new blueprint is being developed to prevent the infection.

15 Dec 2019

NIH-funded research finds differences in energy use by immune T cells in ME/CFS

New findings published in the Journal of Clinical Investigation suggest that specific immune T cells from people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) show disruptions in the way they produce energy.

12 Dec 2019

New approach to broadly acting, highly effective HIV vaccine

Researchers have reported a major advance in the creation of a successful HIV vaccine that is not produced by the host animal.

9 Dec 2019

Transitional T cells could help improve cancer immunotherapy

In chronic viral infections and cancer, T cell dysfunction is sure to be observed. A new study to be published in the journal Immunity shows that before these cells are completely exhausted, there is a transitory stage in which some cells are present with features that are characteristic of neither the stem-like T cells nor the mature but exhausted T cells.

4 Dec 2019

Expansion of HIV treatment eligibility leads to large increase in ART initiation among youth

A new study published as "Editor's Choice" in The Journal of Infectious Diseases found that expansion of HIV treatment eligibility to include those under age 15 led to large and significant increases in initiation of antiretroviral therapy within 30 days of enrollment in care among 10- to 14-year-olds living with HIV.

3 Dec 2019

Study: TBK1 protein promotes cancer development, suppresses immune response to the disease

Researchers at The University of Texas MD Anderson Cancer Center have found that a protein involved in immune response to microbes also can fuel cancer development and suppress immune response to the disease.

3 Dec 2019

Study: Spleen and gut lymph nodes may serve as reservoir replication sites for HIV virus

An international team led by Professor Jerome Estaquier from Universite Laval's Faculty of Medicine and the CHU de Quebec-Universite Laval Research Center may have discovered where in the body HIV takes refuge during antiretroviral treatment.

3 Dec 2019

Many women in Europe are diagnosed at late stage of HIV infection

Many women in the WHO European Region, particularly those in their 40s, are diagnosed at a late stage of HIV infection when their immune system is already starting to fail. They are three to four times more likely to be diagnosed late than younger women.

28 Nov 2019

Experimental vaccine elicits antibodies that can neutralize multiple HIV strains

An experimental HIV vaccine developed by scientists at Scripps Research and the nonprofit vaccine research organization IAVI has reached an important milestone by eliciting antibodies that can neutralize a wide variety of HIV strains.

21 Nov 2019

Dopamine may worsen lung inflammation in asthma

A new study on a mouse model of asthma shows that nerve cells producing dopamine, a neurotransmitter, signal T cells in the body to promote inflammation due to allergic reactions in the lungs during childhood but not in adult mice.

19 Nov 2019

CD4 News and Research

New study gives hope for potentially developing a cure for HIV

Scientists reverse HIV latency, take major scientific step toward curative therapies

Smoking dormant HIV virus out into the open to develop a cure

Immune cells could help kill cancer cells, finds study

Immune cell discovery could hold the key to effective therapies against cancer

ART may not be completely effective in restoring immune protection, study suggests

CD4 T cells are not to be blamed for pushing dengue fever from bad to worse

New mechanism that impairs Treg differentiation and stability in type 1 diabetes discovered

Study finds new drivers of destructive inflammation

The sympathetic nervous system can modulate action of defense cells in autoimmune disease

Novel HIV vaccine shows promise

NIH-funded research finds differences in energy use by immune T cells in ME/CFS

New approach to broadly acting, highly effective HIV vaccine

Transitional T cells could help improve cancer immunotherapy

Expansion of HIV treatment eligibility leads to large increase in ART initiation among youth

Study: TBK1 protein promotes cancer development, suppresses immune response to the disease

Study: Spleen and gut lymph nodes may serve as reservoir replication sites for HIV virus

Many women in Europe are diagnosed at late stage of HIV infection

Experimental vaccine elicits antibodies that can neutralize multiple HIV strains

Dopamine may worsen lung inflammation in asthma

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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